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Cat No. | Product Name | Synonyms | Targets |
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T17548 | Biotin-C5-amino-C5-amino | Others , PROTAC Linker | |
Biotin-C5-amino-C5-amino is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis. | |||
T15146 | DNA2 inhibitor C5 | Others | |
DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM)... | |||
T40007 | Pomalidomide-C5-COOH | Others | |
Pomalidomide-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology. | |||
T18468 | N3-C5-NHS ester | Others | |
N3-C5-NHS ester is a noncleavable ADC linker. N3-C5-NHS ester can be used in the synthesis of antibody-drug conjugates (ADCs). | |||
T10863 | Complement C5-IN-1 | Complement System | |
Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5). | |||
T9270 | C5 Lenalidomide | Others | |
C5 Lenalidomide is an chemical weith inconclusive biological activity. | |||
T18617 | NH2-C5-NH-Boc | PROTAC Linker 23 | Others , PROTAC Linker |
NH2-C5-NH-Boc (PROTAC Linker 23) (PROTAC Linker 23) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. | |||
T60500 | AP-C5 | Parasite | |
AP-C5 is a compound with selective inhibition of guanosine 3',5' cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), with a Pic50 value of 7.2 for cGMP, and can be used in the study of diarrheal diseases. | |||
T39060 | Benzyloxy-C5-PEG1 | Benzyloxy-C5-PEG1 | |
Benzyloxy-C5-PEG1 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T39496 | Thalidomide-O-C5-acid | Thalidomide-O-C5-acid | |
Thalidomide-O-C5-acid is a chemically synthesized conjugate that acts as an E3 ligase ligand-linker and combines the cereblon ligand derived from Thalidomide with a linker commonly utilized in PROTAC technology. | |||
T38830 | Modified MMAF-C5-COOH | Modified MMAF-C5-COOH | |
Modified MMAF-C5-COOH is a drug-linker conjugate for ADC. | |||
T39651 | (S,R,S)-AHPC-C5-NH2 | (S,R,S)-AHPC-C5-NH2,VH032-C5-NH2 | |
(S,R,S)-AHPC-C5-NH2, also known as VH032-C5-NH2, is a synthetic compound designed as an E3 ligase ligand-linker conjugate. This compound combines the VH032-based von Hippel-Lindau (VHL) ligand with a linker, enabling it ... | |||
T39599 | Lenalidomide-C5-amido-Boc | Lenalidomide-C5-amido-Boc | |
Lenalidomide-C5-amido-Boc is a Cereblon ligand derived from Lenalidomide, and serves in the recruitment of CRBN protein. It can be effectively linked to the protein ligand through a linker, resulting in the formation of ... | |||
T61483 | GLP-1R modulator C5 | Glucagon Receptor | |
GLP-1R modulator C5 is a small molecule GLP-1R orthosteric modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study of type II diabetes. | |||
T38999 | Biotin-C4-amide-C5-NH2 | Biotin-C4-amide-C5-NH2 | |
Biotin-C4-amide-C5-NH2 is a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs). | |||
T40079 | Thalidomide-O-C5-NH2 hydrochloride | Thalidomide-O-C5-NH2 hydrochloride | |
Thalidomide-O-C5-NH2 hydrochloride is a synthetic compound consisting of a ligand-linker conjugate with E3 ligase activity. It combines a cereblon ligand based on Thalidomide and a linker commonly utilized in PROTAC tech... | |||
T39900 | Thalidomide-O-amide-C5-NH2 | Thalidomide-O-amide-C5-NH2 | |
Thalidomide-O-amide-C5-NH2 is a chemically synthesized conjugate, serving as an E3 ligase ligand-linker, which combines a cereblon ligand derived from Thalidomide with a linker that is commonly employed in PROTAC technol... | |||
T18667 | (S,R,S)-AHPC-C5-COOH | VH032-C5-COOH | Others |
(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized conjugate designed for E3 ligase ligand-linker applications, combining the VH032 VHL-based ligand with a linker for PROTAC development. VH-032 acts as a selective and... | |||
T78421 | Biotin-C5-Azide | DecarboxyBiotin-N3 | |
Biotin-C5-Azide (DecarboxyBiotin-N3) serves as a biotin reagent, facilitating the synthesis of biotinylated conjugates [1]. | |||
T18638 | Boc-C5-O-C5-O-C6-Cl | PROTAC Linker 2 | Others |
Boc-C5-O-C5-O-C6-Cl (PROTAC Linker 2) is a chemical compound commonly employed as a linker in PROTAC applications. Its primary function is to connect a specific tyrosine kinase inhibitor (TKI) with the E3 recruiting liga... | |||
T18307 | MC(C5)-Val-Cit | Others | |
MC(C5)-Val-Cit is a cleavable ADC linker employed in ADCs synthesis [1]. | |||
T17928 | Lenalidomide-C5-NH2 | E3 ligase Ligand-Linker Conjugates 31,Cereblon Ligand-Linker Conjugates 19 | Others |
Lenalidomide-C5-NH2 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs[1]. | |||
T14576 | Biotin-C5-NHS Ester | Others | |
Biotin-C5-NHS Ester is an alkyl/ether-based linker for PROTAC synthesis[1]. | |||
T18063 | Lenalidomide-acetylene-C5-COOH | Cereblon ligand-linker Conjugate | Others |
Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) serves as a Lenalidomide-based Cereblon ligand that facilitates the recruitment of the CRBN protein. This compound can be connected to the pr... | |||
T18489 | NH2-O-C5-COOH hydrobromide | 6-Aminooxy-hexanoic acid hydrobromide | Others |
NH2-O-C5-COOH (hydrobromide) is an alkyl chain-derived PROteolysis TArgeting Chimera (PROTAC) linker employed for PROTAC synthesis [1]. | |||
T36262 | Thalidomide-NH-C5-NH2 hydrochloride | Pomalidomide 4'-alkylC5-amine | |
Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC5 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functi... | |||
T18445 | N-Methyl-N'-(azido-PEG2-C5)-Cy5 | Others | |
N-Methyl-N'-(azido-PEG2-C5)-Cy5 is a polyethylene glycol (PEG)-based linker that incorporates an azide functionality. This linker is primarily utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1]. | |||
T125394 | Tetromycin C5 | ||
Tetromycin C5 is a useful organic compound for research related to life sciences. The catalog number is T125394 and the CAS number is 205433-86-9. | |||
T18486 | NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 | Others | |
NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a seven-unit cleavable polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker employed in the synthesis of ADCs[1]. | |||
T18670 | (S,R,S)-AHPC-Me-C5-COOH | Others | |
(S,R,S)-AHPC-Me-C5-COOH is a synthetic E3 ligase ligand-linker conjugate consisting of a VHL ligand and a linker. It finds application in PROTAC DT2216[1]. | |||
T18660 | (S,R,S)-AHPC-amido-C5-acid | Others | |
(S,R,S)-AHPC-amido-C5-acid is a chemical compound that contains a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. It can be utilized in the design of XY028-133[1]. | |||
T81421 | Pomalidomide-C5-Dovitinib | PROTACs | |
Pomalidomide-C5-Dovitinib (compound 2) is a PROTAC that links Pomalidomide and Dovitinib via a CRBN connector, exhibiting potent antiproliferative activity in FLT3-ITD+ acute myeloid leukemia (AML) cells. It promotes the... | |||
T17903 | Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH | E3 ligase Ligand-Linker Conjugates 49,Cereblon Ligand-Linker Conjugates 14 | Others |
Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized compound, designed as an E3 ligase ligand-linker conjugate, integrating the cereblon ligand derived from Pomalidomide and a linker employed in PROTAC... | |||
T9915 | Eculizumab | Complement System | |
Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5 | |||
T74727 | CL845-PAB-Ala-Val-C5-MC | ||
CL845-PAB-Ala-Val-C5-MC, a conjugatable STING ligand, derives from the proprietary cyclic dinucleotide CL845 and is designed for bioconjugation. | |||
T77952 | Thalidomide-5-O-C5-NH2 hydrochloride | ||
Thalidomide-5-O-C5-NH2 hydrochloride, a Thalidomide-derived cereblon ligand, facilitates the recruitment of CRBN protein and can be conjugated via a linker to form PROTACs [1]. | |||
T71022 | GI-129471 | ||
GI-129471 is a metalloproteinase inhibitor, specifically blocking TNF-alpha secretion both in vitro and in vivo. | |||
T12862 | SC58451 | COX | |
SC58451 is a novel potent, orally active and selective COX-2 inhibitor.SC58451 showed anti-inflammatory activity in a rat model of arthritis. | |||
T9832 | (Rac)-EC5026 | Urea, N-[3-fluoro-4-(trifluoromethoxy)phenyl]-N'-[1-(2-methyl-1-oxobutyl)-4-piperidinyl]- | Epoxide Hydrolase |
(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) with Ki of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia with Lewy Bodies (DLB) ... | |||
T12860 | SC57666 | COX | |
SC57666 is a highly selective COX2 inhibitor (IC50 at 26 nM) that shows no activity against COX1. | |||
T21876 | DC_AC50 | Apoptosis , Others | |
DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance.DC_AC50 binding to Atox1 and CCS and reducin... | |||
T11147 | EC5026 | BPN-19186 | Epoxide Hydrolase |
EC5026 (BPN-19186) has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators. | |||
TP1648L | [Gln8]-C517 (LH-RH), chicken acetate | [Gln8]-C517 (LH-RH), chicken acetate(47922-48-5 free base) | Others |
[Gln8]-C517 (LH-RH), chicken acetate is an avian hypothalamic peptide that stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions. | |||
T6910 | NSC59984 | p53 | |
NSC59984, a p53 pathway activator, induces mutant p53 protein degradation and p73 activation. | |||
T19000 | HBC514 | Others | |
HBC514, a nonfluorescent HBC-analog, emits strong green fluorescence upon forming a tight complex with Pepper RNA aptamer. | |||
T2242 | Wnt-C59 | C59 | Wnt/beta-catenin , Porcupine |
Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity. | |||
T21302 | UNC569 | UNC 569 | TAM Receptor |
UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amoun... | |||
T14852 | C527 | DUB | |
C527 is a is a pan DUB enzyme inhibitor. Which has a high potency for the USP1/UAF1 complex (IC50=0.88 μM). | |||
T69289 | BW284C51 | ||
BW284C51 is a selective acetylcholinesterase inhibitor. It is also a nicotinic antagonist | |||
T26937 | C562-1101 | ||
C562-1101 is a novel potent botulinum neurotoxin serotype E (BoNT/E) inhibitor. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8240 | Cis-5-Dodecenoic Acid | Others | |
Cis-5-Dodecenoic Acid is a monounsaturated fatty acid that has a C12 chain as a backbone and a cis double bond at the C5 position. | |||
T1688 | Pregnanediol | 5Beta-Pregnane-3Alpha,20alpha-Diol,Pregnandiol | Estrogen/progestogen Receptor , Endogenous Metabolite |
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol(5Beta-Pregnane-3Alpha,20alpha-Diol) has two hydroxyl groups, at 3-alpha a... | |||
T4794 | Glutaric acid | Endogenous Metabolite | |
Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan | |||
TN5930 | Ocotillone | ||
Ocotillone has potent antibacterial activity against Gram-negative bacteria, P. aeruginosa and S. typhimurium, that are without hemolytic activity, whereas it has weak antimicrobial activity against Gram-positive bacteri... | |||
T81201 | Sartorypyrone B | ||
Sartorypyrone B, a 2β-acetoxyl analogue of chevalone C, is derived from the ethyl acetate extract of the culture of Neosartorya tsunodae (KUFC 9213), a fungus associated with marine sponges. This compound demonstrates po... | |||
T35754 | Aszonapyrone A | ||
Aszonapyrone A is a meroditerpene fungal metabolite that has been found in Neosartorya and has diverse biological activities.1,2,3 It inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, ... | |||
T38484 | Englerin A | (-)-Englerin A | TRP/TRPV Channel |
Englerin A, a TRPC4 and TRPC5 channel agonist, is a compound from the East African plant Phyllanthus engleri with analgesic, anti-inflammatory, and anticancer activities that induces necrosis in human renal cancer cells. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05057 | Complement C5 Protein, Human, Recombinant (His & FLAG) | Human | HEK293 Cells |
Complement C5 Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 188.8 kDa and the accession number is P01031. | |||
TMPY-00653 | Complement C5 Protein, Human, Recombinant (Complement C5a) | Human | E. coli |
Complement C5 Protein, Human, Recombinant (Complement C5a) is expressed in E. coli expression system. The predicted molecular weight is 8.3 kDa and the accession number is P01031. | |||
TMPH-03270 | Complement C5 Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
Complement C5 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 14.0 kDa and the accession number is P08650. | |||
TMPY-06814 | Complement C5 Protein, Human, Recombinant (Flag) | Human | HEK293 Cells |
Complement C5 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag. The predicted molecular weight is 187.36 kDa and the accession number is NP_001726.2. | |||
TMPY-06538 | Complement C5 Protein, Cynomolgus, Recombinant | Cynomolgus | HEK293 Cells |
Complement C5 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 8.41 kDa and the accession number is XP_005580972.1. | |||
TMPH-03107 | Complement C5a Protein, Pig, Recombinant (His) | Sus scrofa (Pig) | P. pastoris (Yeast) |
Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, ... | |||
TMPY-06137 | Complement C5 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 188.1 kDa and the accession number is XP_005580972.1. | |||
TMPK-01268 | Complement C2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to health... | |||
TMPH-02607 | Complement factor B Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convert... | |||
TMPY-04902 | Complement C5a Protein, Mouse, Recombinant | Mouse | E. coli |
Complement C5a Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 kDa and the accession number is P06684. | |||
TMPY-06806 | GPRC5D Protein-VLP, Human, Recombinant (GFP) | Human | HEK293 Cells |
GPRC5D Protein, Human, Recombinant, Fluorescent is expressed in HEK293 mammalian cells. The predicted molecular weight is 65.81 kDa and the accession number is Q9NZD1. | |||
TMPY-06719 | GPRC5D Protein, Human, Recombinant (His & FLAG) | Human | HEK293 Cells |
GPRC5D Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 32.83 kDa and the accession number is Q9NZD1. | |||
TMPH-02121 | SLC5A5 Protein, Human, Recombinant (B2M & His) | Human | E. coli |
May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant ... | |||
TMPY-06601 | GPRC5D Protein, Human, Recombinant, Biotinylated | Human | HEK293 Cells |
GPRC5D Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is Q9NZD1-1. | |||
TMPH-00992 | BIRC5 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
BIRC5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-02197 | TXNDC5 Protein, Human, Recombinant | Human | E. coli |
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant is expressed in E. coli expression sy... | |||
TMPH-02533 | BIRC5 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
BIRC5 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is O70201. | |||
TMPH-02532 | BIRC5 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
BIRC5 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.3 kDa and the accession number is O70201. | |||
TMPK-01193 | GPRC5D Protein-VLP, Mouse, Recombinant | Mouse | HEK293 Cells |
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GP... | |||
TMPY-04133 | UNC5B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ... | |||
TMPY-06718 | GPRC5D Protein, Human, Recombinant (His & FLAG), Detergent | Human | HEK293 Cells |
GPRC5D Protein, Human, Recombinant (His & FLAG), Detergent is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 32.83 kDa and the accession number is Q9NZD1. | |||
TMPY-06807 | GPRC5D Protein-VLP, Mouse, Recombinant (Flag) | Mouse | HEK293 Cells |
GPRC5D Protein, Mouse, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag. The predicted molecular weight is 35.8 kDa and the accession number is Q9JIL6-2. | |||
TMPH-03074 | UBC5A Protein, Japonica rice, Recombinant (His & Myc) | Rice | E. coli |
E2 conjugating enzyme that associates with the E3 ubiquitin-protein ligase EL5 to mediates ubiquitination of target proteins. UBC5A Protein, Japonica rice, Recombinant (His & Myc) is expressed in E. coli expression syste... | |||
TMPY-03928 | CLEC5A Protein, Rhesus, Recombinant (mFc) | Rhesus | HEK293 Cells |
CLEC5A Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45.3 kDa and the accession number is A0A1D5QX52. | |||
TMPH-02120 | SLC5A5 Protein, Human, Recombinant (His) | Human | E. coli |
Mediates iodide uptake in the thyroid gland. SLC5A5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 17.4 kDa and the accession number is Q92... | |||
TMPH-01022 | C5AR1 Protein-VLP, Human, Recombinant (His) | Human | HEK293 Cells |
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transm... | |||
TMPH-01709 | Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression... | |||
TMPH-02032 | GPRC5A Protein, Human, Recombinant (GST) | Human | E. coli |
Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-prote... | |||
TMPY-03872 | CLEC5A Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
CLEC5A Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.6 kDa and the accession number is F7GAV1. | |||
TMPH-02315 | XRCC5 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a... | |||
TMPK-00528 | GPRC5D Protein-VLP, Cynomolgus, Recombinant | Cynomolgus | HEK293 Cells |
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GP... | |||
TMPY-00507 | UNC5B Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ... | |||
TMPH-02196 | TXNDC5 Protein, Human, Recombinant (GST) | Human | E. coli |
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant (GST) is expressed in E. coli express... | |||
TMPY-04003 | UNC5B Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ... | |||
TMPJ-01363 | CLIC5 Protein, Human, Recombinant (His) | Human | E. coli |
Chloride Intracellular Channel Protein 5 (CLIC5) is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain. Chloride intracellular channels are involved in... | |||
TMPH-02119 | SLC5A2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1.; Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affini... | |||
TMPY-06494 | GPRC5D Protein-VLP, Human, Recombinant | Human | HEK293 Cells |
GPRC5D Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is Q9NZD1-1. | |||
TMPK-01218 | MDL-1/CLEC5A Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
MDL-1/CLEC5A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 46.2 kDa and the accession number is Q9R007-1. | |||
TMPH-02314 | XRCC5 Protein, Human, Recombinant (His & MBP) | Human | Baculovirus Insect Cells |
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a... | |||
TMPY-03760 | CLEC5A Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 Cells |
CLEC5A Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is A0A1D5QX52. | |||
TMPY-05459 | Complement C5a Protein, Mouse, Recombinant, Biotinylated | Mouse | E. coli |
Complement C5a Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 9 kDa and the accession number is P06684. | |||
TMPH-01023 | C5AR1 Protein, Human, Recombinant (Cell-Free, His) | Human | E. coli |
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transm... | |||
TMPY-00999 | UNC5A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cu... | |||
TMPK-01205 | MDL-1/CLEC5A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
MDL-1/CLEC5A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 46 kDa and the accession number is Q9NY25-1. | |||
TMPY-00648 | UNC5A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cu... | |||
TMPH-03038 | Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO) | Naja kaouthia | E. coli |
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to fo... | |||
TMPH-02972 | VDB Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. VDB Protein, Mouse, Recombi... | |||
TMPH-02844 | Properdin Protein, Mouse, Recombinant (His) | Mouse | E. coli |
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Comple... | |||
TMPH-02845 | Properdin Protein, Mouse, Recombinant (His & Myc) | Mouse | HEK293 Cells |
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Comple... | |||
TMPH-02605 | Complement C4-B Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of imm... | |||
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