Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 g | In stock | $ 29.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 29.00 |
Description | Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan |
In vitro | Glutaric acid, at concentrations of 1 and 2 mM, significantly reduces TRAP measurement by up to 28%, showcasing a dose-dependent efficacy (β=0.77; P<0.001). Additionally, a strong inverse correlation is observed between chemiluminescence and TRAP levels (β=0.81; P<0.001), indicating glutaric acid's potential impact on these parameters. Despite not affecting the activities of catalase (Cat) and superoxide dismutase (SOD), glutaric acid notably inhibits glutathione peroxidase (GPx) activity by up to 46%, starting at a minimal concentration of 0.5 mM. This inhibition is further confirmed to follow a dose-dependent pattern, beginning from concentrations as low as 0.05 mM[2], underscoring its potent and variable effect based on the dosage administered. |
Molecular Weight | 132.11 |
Formula | C5H8O4 |
CAS No. | 110-94-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: Soluble
DMSO: 55 mg/mL (416.32 mM)
H2O: 5 mg/mL
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Glutaric acid 110-94-1 Metabolism Endogenous Metabolite Inhibitor inhibit inhibitor