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Search Result

Search Results for " emt "

Targets

Wnt/beta-catenin

49

Compounds

5

Natural Products

21

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T11190 EMT inhibitor-1 Wnt/beta-catenin
EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.
T11187 EMT inhibitor-2 Others
EMT Inhibitor-2, targeting both CYP3A4 testosteron and CYP2C9, exhibits inhibitory effects with IC50 values of 49.72 and 5.54 μM, respectively. Furthermore, it effectively impedes the epithelial-mesenchymal transition (E...
T21981 Phthalazinone pyrazole Aurora Kinase
Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.
T9205 NCGC00378430 Phosphatase , Others
NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor that disrupts the SIX1/EYA2 complex, EMT, and Metastasis.
T15735 Leptomycin B CI 940,LMB CRM1 , Antibiotic , Antifungal
Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a ...
T0459 Sulindac Arthrocine,MK-231,Clinoril,Sulindac sulfoxide COX , Autophagy
Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cycl...
T9919 Alemtuzumab Others
Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes.
T64167 Ifebemtinib IN-10018,BI-853520 FAK
Ifebemtinib (BI-853520) is an orally active and potent inhibitor of adhesion plaque kinase (FAK) (IC50=1 nM) with anti-tumour activity that inhibits globule formation and in situ tumour growth in malignant pleural mesoth...
T76890 Petosemtamab MCLA 158 EGFR
Petosemtamab (MCLA 158) is a highly potent monoclonal antibody against EGFR (Kd: 0.22 nM) and LGR5 (Kd: 0.86 nM). Petosemtamab promotes EGFR signaling disruption and receptor breakdown in LGR5+ cancer cells. Petosemtamab...
T64167L Ifebemtinib FA BI-853520 FA（1227948-82-4 Free base) FAK
Ifebemtinib FA (BI-853520 FA) is an orally active and potent inhibitor of adhesion patch kinase (FAK) with anticancer and antiproliferative activity for the study of ovarian and lung cancer.
T9901A-003 Gemtuzumab CDP-771,CMA-676
Gemtuzumab(CMA-676) is a monoclonal antibody directed against the CD33 antigen and consists of a recombinant humanized IgG4 antibody.Gemtuzumab can be used to synthesize Gemtuzumab ozogamicin, an antibody coupled compoun...
T3966 Tirasemtiv CK-2017357 Others
Tirasemtiv (CK-2017357)(CK 2017357) is a small-molecule fast-skeletal-troponin activator, with a potential treatment for muscle weakness and neuromuscular dysfunction.
T6214 Emtricitabine FTC,Emtriva,BW1592 HIV Protease , Reverse Transcriptase
Emtricitabine (FTC) (FTC), a nucleoside reverse transcriptase inhibitor, exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B virus.
T16728 Reldesemtiv CK-2127107 Others
Reldesemtiv (CK-2127107) is a selective activator of fast skeletal muscle troponin with an EC50 of 3.4 μM. Reldesemtiv increases exercise performance in the heart failure model.
T11189 Emtricitabine S-oxide Emtricitabine Degradant-III,Emtricitabine sulfoxide HIV Protease , Reverse Transcriptase
Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine sulfoxide, represents a significant degradation byproduct of ...
T77179 Remtolumab
Remtolumab (ABT-122), a dual-variable domain immunoglobulin, neutralizes tumor necrosis factor α (TNFα) and IL-17A, demonstrating dual inhibition of both. This compound is utilized in rheumatoid arthritis (RA) research [...
T69639 Sevasemten
Sevasemten is an allosteric inhibitor that targets skeletal muscle myosin. It displays selectivity in its inhibition, demonstrated by IC50 values of ≤10 μM for skeletal muscle myosin and >100 μM for cardiac myosin, respe...
T36647 Trastuzumab emtansine Others
Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that combines the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of DM1, a microtubule-inhibitory deriv...
T77176 Elgemtumab
Elgemtumab (LJM716) is a fully human IgG monoclonal antibody that specifically targets HER3, inhibiting both ligand-dependent and independent HER3 signal transduction and cell proliferation. This function showcases its s...
T70596 Emtricitabine triphosphate (-)-Emtricitabine triphosphate
Emtricitabine triphosphate ((-)-Emtricitabine triphosphate), the phosphorylated anabolite of Emtricitabine, serves as a nucleoside reverse transcriptase inhibitor and antiretroviral agent against HIV and HBV [1] [2].
T81299 Remternetug LY3372993
Remternetug is a humanized IgG1-kappa monoclonal antibody that targets the N3pGlu peptide of the amyloid beta A4 precursor protein (APP) Aβ42. It specifically binds to the pyroglutamate-modified form of Aβ, which is impl...
T80566 Temtokibart
Temtokibart is a humanized IgG1 λ2 antibody that specifically targets IL22RA1, and is expressed by cells that are deficient in the glutamine synthetase gene.
T78131 Emtricitabine triphosphate tetrasodium salt (-)-Emtricitabine triphosphate tetrasodium salt Reverse Transcriptase
Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleoside reverse transcriptase inhibitor that is effective against HIV ...
T71868 Cemtirestat
Cemtirestat is an aldose reductase inhibitor
T75029 HEMTAC CDK4/6 degrader 1
HEMTAC CDK4/6 degrader 1 is a PROTAC connected by ligands for HSP90 and CDK4/6 with a K d value of 35.7 μM. HEMTAC CDK4/6 degrader 1 induces CDK4/6 degradation in B16F10 melanoma cells. HEMTAC CDK4/6 degrader 1 arrests c...
T78047 Gemtuzumab ozogamicin
Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) that comprises a monoclonal antibody specific to CD33 conjugated to a cytotoxic agent derived from Calicheamicin. It is utilized in the investigation of acute mye...
T73009 Vemtoberant
Vemtoberant, a β3 Adrenergic Receptor antagonist, is utilized in the research of disorders mediated by the β3 adrenergic receptor, including heart failure.
T4252 ML327 c-Myc , Autophagy
ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).
T73300 AXL-IN-13 FLT , TAM Receptor , PDGFR , TGF-beta/Smad
AXL-IN-13 is a potent and orally active AXL inhibitor with an IC50 value of 1.6 nM and a Kd value of 0.26 nM.AXL-IN-13 exhibits anticancer activity, reverses TGF-β1-induced epithelial-mesenchymal transition (EMT) and inh...
T38752 EW-7195 ALK , TGF-beta/Smad
EW-7195 is a selective and potent inhibitor of ALK5 (TGFβR1) with an IC50 value of 4.83 nM.EW-7195 has an affinity for ALK5 that is more than 300-fold higher than that of p38α.EW-7195 has an inhibitory effect on TGF-β1-i...
T11793 KY-05009 Wnt/beta-catenin
KY-05009 is a chemical compound that effectively suppresses TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells, reduces TNIK protein expression and the transcriptional activity o...
T36696 DMBA
7,12-Dimethylbenz[a]anthracene (DMBA) is a polycyclic aromatic hydrocarbon (PAH) that has been found in tobacco smoke and diesel exhaust and has carcinogenic activity.1,2It undergoes metabolic activation by numerous enzy...
T70841 Osteosarcoma-IN-D14
Osteosarcoma-IN-D14 is an inhibitor of migration and invasion of osteosarcoma cells mediated by p53, regulating EMT-related genes.
T83075 Anticancer agent 94
Anticancer agent 94, a 4-Hydroxycoumarin derivative, inhibits lung cancer cell invasion and migration by modulating the expression of epithelial-mesenchymal transition (EMT) effectors [1].
T83076 Anticancer agent 93
Anticancer Agent 93, a 4-Hydroxycoumarin derivative, inhibits the invasion and migration of lung cancer cells through modulation of epithelial-mesenchymal transition (EMT) effector expression [1].
T72880 PI3K/AKT-IN-2
PI3K/AKT-IN-2, a dual inhibitor of PI3K and AKT, prevents the epithelial-mesenchymal transition (EMT) and promotes apoptosis. Additionally, it impedes tubulin polymerization.
T73035 STAT3-IN-15
STAT3-IN-15, a potent and orally active inhibitor targeting STAT3, effectively combats idiopathic pulmonary fibrosis (IPF) by hindering STAT3 phosphorylation. Additionally, it impedes TGF-β1-induced migration and deforma...
T73039 CYP1B1-IN-3
CYP1B1-IN-3 is a potent, selective inhibitor of CYP1B1, exhibiting IC50 values of 6.6 nM for CYP1B1, 347.3 nM for CYP1A1, and >10000 nM for CYP1A2. It also impedes cell migration and invasion, and inhibits the P-gp, AKT/...
T73547 CPUL1
CPUL1, a TrxR inhibitor, exhibits proliferation-inhibitory and anti-metastatic effects on A549 cells by modulating epithelial-mesenchymal transition (EMT) through the induction of ROS-mediated ERK/JNK signaling, achieved...
T63768 Antitumor agent-78
Antitumor agent-78 inhibits GPx-4 and elevates COX2, leading to ferroptosis. antitumor agent-78 activates the tumor cell intrinsic apoptotic pathway (Bax-Bcl-2-caspase-3) and inhibits the epithelial mesenchymal transitio...
T62822 CT1-3
CT1-3 is a potent anti-cancer agent. CT1-3 regulates the JNK/Bcl-2/Bax/XIAP pathway, which induces mitochondria-mediated apoptosis. CT1-3 regulates the E-cadherin/Snail axis to inhibit epithelial mesenchymal transition (...
T62814 Antitumor agent-77
Antitumor agent-77 inhibits the growth and migration of cancer cells and has anticancer effects. antitumor agent-77 inhibits GPx-4 and enhances COX2-induced iron sagging. antitumor agent-77 activates the intrinsic apopto...
T61585 Sulindac sodium
Sulindac (sodium) (MK-231) is an orally active nonsteroidal anti-inflammatory agent. Sulindac (sodium) is used to reduce pain, swelling, and joint stiffness from arthritis. Sulindac is also used for the research of arthr...
T36497 CAY10735 CAY10735
CAY10735 is an anticancer compound.1 It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.674-11.56 μM). CAY10735 inhibits migration of and the epithelial-to-mese...
T71884 ß-Carboline-1-carboxylic acid
β-Carboline-1-carboxylic acid is an alkaloid that has been found in P. quassioides and has diverse biological activities. It reduces LPS-induced increases in MCP-1, TNF-α, IL-6, and IL-1β levels in RAW 264.7 cells when u...
T36460 CAY10736 CAY10736
CAY10736 is an anticancer compound.1 It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.827-9.89 μM). CAY10736 inhibits migration and epithelial-to-mesenchymal ...
T79789 DT-6 TGF-beta/Smad
DT-6, a potent TGF-β1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showing potential for cancer research applications [1].
T82673 CPF-7 Caerulein precursor fragment
CPF-7 (Caerulein precursor fragment), an insulinotropic peptide, promotes insulin secretion and drives epithelial-mesenchymal transition via Snai1 upregulation in PANC-1 ductal cells. Moreover, it induces exocrine plasti...
T69685 AGPS-IN-2i MMP
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferat...

Compounds

EMT inhibitor-1
T11190
Synonym:
Target: Wnt/beta-catenin
EMT inhibitor-2
T11187
Synonym:
Target: Others
Phthalazinone pyrazole
T21981
Synonym:
Target: Aurora Kinase
NCGC00378430
T9205
Synonym:
Target: Phosphatase, Others
Leptomycin B
T15735
Synonym: CI 940,LMB
Target: CRM1, Antibiotic, Antifungal
Sulindac
T0459
Synonym: Arthrocine,MK-231,Clinoril,Sulindac sulfoxide
Target: COX, Autophagy
Alemtuzumab
T9919
Synonym:
Target: Others
Ifebemtinib
T64167
Synonym: IN-10018,BI-853520
Target: FAK
Petosemtamab
T76890
Synonym: MCLA 158
Target: EGFR
Ifebemtinib FA
T64167L
Synonym: BI-853520 FA（1227948-82-4 Free base)
Target: FAK
Gemtuzumab
T9901A-003
Synonym: CDP-771,CMA-676
Target:
Tirasemtiv
T3966
Synonym: CK-2017357
Target: Others
Emtricitabine
T6214
Synonym: FTC,Emtriva,BW1592
Target: HIV Protease, Reverse Transcriptase
Reldesemtiv
T16728
Synonym: CK-2127107
Target: Others
Emtricitabine S-oxide
T11189
Synonym: Emtricitabine Degradant-III,Emtricitabine sulfoxide
Target: HIV Protease, Reverse Transcriptase
Remtolumab
T77179
Synonym:
Target:
Sevasemten
T69639
Synonym:
Target:
Trastuzumab emtansine
T36647
Synonym:
Target: Others
Elgemtumab
T77176
Synonym:
Target:
Emtricitabine triphosphate
T70596
Synonym: (-)-Emtricitabine triphosphate
Target:
Remternetug
T81299
Synonym: LY3372993
Target:
Temtokibart
T80566
Synonym:
Target:
Emtricitabine triphosphate tetrasodium salt
T78131
Synonym: (-)-Emtricitabine triphosphate tetrasodium salt
Target: Reverse Transcriptase
Cemtirestat
T71868
Synonym:
Target:
HEMTAC CDK4/6 degrader 1
T75029
Synonym:
Target:
Gemtuzumab ozogamicin
T78047
Synonym:
Target:
Vemtoberant
T73009
Synonym:
Target:
ML327
T4252
Synonym:
Target: c-Myc, Autophagy
AXL-IN-13
T73300
Synonym:
Target: FLT, TAM Receptor, PDGFR, TGF-beta/Smad
EW-7195
T38752
Synonym:
Target: ALK, TGF-beta/Smad
KY-05009
T11793
Synonym:
Target: Wnt/beta-catenin
DMBA
T36696
Synonym:
Target:
Osteosarcoma-IN-D14
T70841
Synonym:
Target:
Anticancer agent 94
T83075
Synonym:
Target:
Anticancer agent 93
T83076
Synonym:
Target:
PI3K/AKT-IN-2
T72880
Synonym:
Target:
STAT3-IN-15
T73035
Synonym:
Target:
CYP1B1-IN-3
T73039
Synonym:
Target:
CPUL1
T73547
Synonym:
Target:
Antitumor agent-78
T63768
Synonym:
Target:
CT1-3
T62822
Synonym:
Target:
Antitumor agent-77
T62814
Synonym:
Target:
Sulindac sodium
T61585
Synonym:
Target:
CAY10735
T36497
Synonym: CAY10735
Target:
ß-Carboline-1-carboxylic acid
T71884
Synonym:
Target:
CAY10736
T36460
Synonym: CAY10736
Target:
DT-6
T79789
Synonym:
Target: TGF-beta/Smad
CPF-7
T82673
Synonym: Caerulein precursor fragment
Target:
AGPS-IN-2i
T69685
Synonym:
Target: MMP
Cat No. Product Name Synonyms Targets
T13741 Isoviolanthin Others
Isoviolanthin reduces the migratory and invasive capacities of TGF-β1-treated HCC cells without cytotoxic effects on normal live cells and has potential as a therapeutic agent for the treatment of advanced-stage metastat...
T0518 Methacycline hydrochloride Rondomycin,Methacycline HCl ribosome , Antibacterial , Antibiotic
Methacycline hydrochloride (Rondomycin) is a broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period.
TN1088 3,​5,​6,​7,​8,​3',​4'-​Heptemthoxyflavone 3,3',4',5,6,7,8-heptamethoxyflavone Others
3,5,6,7,8,3',4'-Heptemthoxyflavone has neuroprotective, chemopreventive, anti-allergic, anti-inflammatory, immunomodulatory, anti-aging and photoprotective effects; it inhibits collagenase activity and induces type I pro...
T4S1050 Pristimerin Celastrol methyl ester NF-κB , Antibacterial
1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell...
TN2229 Soyasaponin Ac Others
Soyasaponin Ac can decrease the drug resistance via EMT pathway and weaken the migration ability of ovarian cancer cells.

Natural Products

Isoviolanthin
T13741
Synonym:
Target: Others
Methacycline hydrochloride
T0518
Synonym: Rondomycin,Methacycline HCl
Target: ribosome, Antibacterial, Antibiotic
3,​5,​6,​7,​8,​3',​4'-​Heptemthoxyflavone
TN1088
Synonym: 3,3',4',5,6,7,8-heptamethoxyflavone
Target: Others
Pristimerin
T4S1050
Synonym: Celastrol methyl ester
Target: NF-κB, Antibacterial
Soyasaponin Ac
TN2229
Synonym:
Target: Others

Recombinant Proteins

Species：
Human (18)
Mouse (2)
Cynomolgus (1)
Expression System：
HEK293 Cells (11)
Baculovirus Insect Cells (4)
E. coli (4)
P. pastoris (Yeast) (2)
Tag：
C-His (4)
N-hFc (4)
N-6xHis (3)
C-His-Avi (2)
C-hFc (2)
His, GST (2)
GST (1)
N-10xHis, C-Myc (1)
N-6xHis-SUMO (1)
N-GST (1)
Cat No. Product Name Species Expression System
TMPY-04570 ITK Protein, Mouse, Recombinant (aa 351-619, His & GST) Mouse Baculovirus Insect Cells
ITK Protein, Mouse, Recombinant (aa 351-619, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 58.4 kDa and the accession number is Q03526.
TMPY-05249 ITK Protein, Human, Recombinant (Actived By LCK, GST) Human Baculovirus Insect Cells
ITK Protein, Human, Recombinant (Actived By LCK, GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 57.7 kDa and the accession number is Q08881.
TMPY-00322 DEC-205 Protein, Human, Recombinant (His) Human HEK293 Cells
LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp...
TMPK-00743 LGR-5 Protein, Human, Recombinant (hFc) Human HEK293 Cells
G protein-coupled receptor 5 (LGR5), known as a stem cell marker for colon cancer and gastric cancer, can serve as a novel GSC marker involved in EMT and a therapeutic target in glioma.LGR5 is a new functional GSC marker...
TMPK-00073 TDGF1/Cripto Protein, Human, Recombinant (His) Human HEK293 Cells
TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, an...
TMPY-05160 PFKP Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
PFKP plays a critical role in cell proliferation in breast cancer cells. PFKP is necessary for starvation-mediated autophagy, glycolysis, and EMT, thereby promoting the malignant progression of OSCC. The Snail-PFKP axis ...
TMPK-00820 AREG Protein, Human, Recombinant (hFc) Human HEK293 Cells
Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic ca...
TMPK-00563 EPHB2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated p...
TMPK-00270 TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled Human HEK293 Cells
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR...
TMPK-00271 TPBG/5T4 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR...
TMPY-04203 RAB1B Protein, Human, Recombinant (hFc) Human HEK293 Cells
RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells. Moreover, down-regulation of RAB1B was also found to promote the proliferation and migration of TNBC ...
TMPH-02226 TEAD3 Protein, Human, Recombinant (His & SUMO) Human E. coli
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is...
TMPH-02225 TEAD2 Protein, Human, Recombinant (His & Myc) Human E. coli
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is...
TMPY-01576 Artemin Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored...
TMPJ-00157 CD82 Protein, Human, Recombinant (hFc) Human HEK293 Cells
CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemoki...
TMPY-04930 Notch 2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
NOTCH2 (Notch Receptor 2) is a Protein Coding gene. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of dev...
TMPH-02222 TEAD1 Protein, Human, Recombinant (His) Human E. coli
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is...
TMPY-01000 BVES Protein, Human, Recombinant (GST) Human E. coli
Blood vessel epicardial substance (BVES), or POPDC1, is a tight junction-associated transmembrane protein that modulates epithelial-to-mesenchymal transition (EMT) via junctional signaling pathways. BVES plays a protecti...
TMPY-03046 APCDD1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, res...
TMPH-03764 YAP1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor su...
TMPH-02217 SMARCA4 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic acti...
ITK Protein, Mouse, Recombinant (aa 351-619, His & GST)
TMPY-04570
Species: Mouse
Expression System: Baculovirus Insect Cells
ITK Protein, Human, Recombinant (Actived By LCK, GST)
TMPY-05249
Species: Human
Expression System: Baculovirus Insect Cells
DEC-205 Protein, Human, Recombinant (His)
TMPY-00322
Species: Human
Expression System: HEK293 Cells
LGR-5 Protein, Human, Recombinant (hFc)
TMPK-00743
Species: Human
Expression System: HEK293 Cells
TDGF1/Cripto Protein, Human, Recombinant (His)
TMPK-00073
Species: Human
Expression System: HEK293 Cells
PFKP Protein, Human, Recombinant (His & GST)
TMPY-05160
Species: Human
Expression System: Baculovirus Insect Cells
AREG Protein, Human, Recombinant (hFc)
TMPK-00820
Species: Human
Expression System: HEK293 Cells
EPHB2 Protein, Cynomolgus, Recombinant (His)
TMPK-00563
Species: Cynomolgus
Expression System: HEK293 Cells
TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled
TMPK-00270
Species: Human
Expression System: HEK293 Cells
TPBG/5T4 Protein, Human, Recombinant (His & Avi)
TMPK-00271
Species: Human
Expression System: HEK293 Cells
RAB1B Protein, Human, Recombinant (hFc)
TMPY-04203
Species: Human
Expression System: HEK293 Cells
TEAD3 Protein, Human, Recombinant (His & SUMO)
TMPH-02226
Species: Human
Expression System: E. coli
TEAD2 Protein, Human, Recombinant (His & Myc)
TMPH-02225
Species: Human
Expression System: E. coli
Artemin Protein, Mouse, Recombinant (hFc)
TMPY-01576
Species: Mouse
Expression System: HEK293 Cells
CD82 Protein, Human, Recombinant (hFc)
TMPJ-00157
Species: Human
Expression System: HEK293 Cells
Notch 2 Protein, Human, Recombinant (His)
TMPY-04930
Species: Human
Expression System: Baculovirus Insect Cells
TEAD1 Protein, Human, Recombinant (His)
TMPH-02222
Species: Human
Expression System: E. coli
BVES Protein, Human, Recombinant (GST)
TMPY-01000
Species: Human
Expression System: E. coli
APCDD1 Protein, Human, Recombinant (hFc)
TMPY-03046
Species: Human
Expression System: HEK293 Cells
YAP1 Protein, Human, Recombinant (His)
TMPH-03764
Species: Human
Expression System: P. pastoris (Yeast)
SMARCA4 Protein, Human, Recombinant (His)
TMPH-02217
Species: Human
Expression System: P. pastoris (Yeast)
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