Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine sulfoxide, represents a significant degradation byproduct of Emtricitabine.
Description | Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine sulfoxide, represents a significant degradation byproduct of Emtricitabine. |
In vitro | Emtricitabine degrades over 51%, 13% and 53% during acid, base and oxidative degradation respectively followed by formation of three major degradation products (Degradant-I to Degradant-III).Emtricitabine, an antiretroviral agent is used to evaluate degradation pathways under different stress conditions in order to identify degradation products as prescribed by ICH guidelines. |
Synonyms | Emtricitabine sulfoxide, Emtricitabine Degradant-III |
Molecular Weight | 263.25 |
Formula | C8H10FN3O4S |
CAS No. | 152128-77-3 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Emtricitabine S-oxide 152128-77-3 Microbiology/Virology Proteases/Proteasome Reverse Transcriptase HIV Protease Emtricitabine sulfoxide Emtricitabine Degradant-III Emtricitabine Soxide Emtricitabine S oxide Inhibitor inhibitor inhibit