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Emtricitabine S-oxide
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Catalog No. T11189Cas No. 152128-77-3
Alias Emtricitabine sulfoxide, Emtricitabine Degradant-III
Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine sulfoxide, represents a significant degradation byproduct of Emtricitabine.
Emtricitabine S-oxide
😃Good
Catalog No. T11189Alias Emtricitabine sulfoxide, Emtricitabine Degradant-IIICas No. 152128-77-3
Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine sulfoxide, represents a significant degradation byproduct of Emtricitabine.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $123 | 35 days | |
| 10 mg | $950 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine sulfoxide, represents a significant degradation byproduct of Emtricitabine. |
| In vitro | Emtricitabine, an antiretroviral agent, undergoes degradation under various stress conditions—acidic, basic, and oxidative—resulting in over 51%, 13%, and 53% degradation respectively, and yielding three major degradation products (Degradant-I to Degradant-III). This process aligns with ICH guidelines to elucidate degradation pathways and identify degradation products of emtricitabine. |
| Alias | Emtricitabine sulfoxide, Emtricitabine Degradant-III |
| Molecular Weight | 263.25 |
| Formula | C8H10FN3O4S |
| Cas No. | 152128-77-3 |
| Relative Density. | 2.02 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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