store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 213.00 | |
2 mg | In stock | $ 359.00 | |
5 mg | In stock | $ 652.00 | |
10 mg | In stock | $ 928.00 | |
25 mg | In stock | $ 1,390.00 | |
50 mg | In stock | $ 1,870.00 | |
100 mg | In stock | $ 2,530.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 297.00 |
Description | Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. |
Synonyms | CI 940, LMB |
Molecular Weight | 540.73 |
Formula | C33H48O6 |
CAS No. | 87081-35-4 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 70 mg/mL (129.45 mM), Sonification is recommended
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Leptomycin B 87081-35-4 Membrane transporter/Ion channel Microbiology/Virology CRM1 Antifungal Antibiotic CI-940 XPO1 Chromosomal Maintenance 1 Fungal inhibit EMT CI 940 p53 nuclear export mutation EGFR CI940 NSCLC resistance Inhibitor cancer Exportin 1 KRAS LMB inhibitor