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Search Results for " ptp "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T7541	PTP inhibitor 1	PTP Inhibitor II	Phosphatase
	PTP inhibitor 1 is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)),with Ki of128 μM.		Phosphatase
T22137	PTP Inhibitor IV		Others
	PTP Inhibitor IV is an effective protein tyrosine phosphatase (PTP) inhibitor, which can selectively inhibit DUSP14 phosphatase activity (IC50.5.21μm). PTP Inhibitor IV inhibited SHP-2, PTP1B, PTp-ε, PTP Meg-2, PTP-σ, PT...		Others
T10927	Cyt-PTPε Inhibitor-1	Cyt-PTP\|A Inhibitor-1	Phosphatase , Src
	Cyt-PTPε Inhibitor-1 (A Inhibitor-1) is an inhibitor of cytosolic protein tyrosine phosphatase ε. Cyt-PTPε Inhibitor-1 blocks the dephosphorylation of c-Src and exhibits anti-osteoclastic activity.		Phosphatase , Src
T6667	SF1670	PTP CD45 Inhibitor,PTPase CD45 Inhibitor	Phosphatase , PTEN , Autophagy
	SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.		Phosphatase , PTEN , Autophagy
T80870	VE-PTP-IN-1
	VE-PTP-IN-1 (compound 2) is a selective inhibitor of the vascular endothelial protein tyrosine phosphatase (VE-PTP), possessing weakly acidic properties. It is associated with the regulation of vascular homeostasis and a...
T7084	2-Bromo-4'-hydroxyacetophenone	SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide	Phosphatase
	2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SH...		Phosphatase
T15243	Ertiprotafib	PTP 112	Phosphatase , PPAR
	Ertiprotafib is a PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist inhibitor ( IC50s: 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPARα/PPARβ).		Phosphatase , PPAR
T39856	Purine riboside triphosphate	PTP,Purine riboside triphosphate
	Purine riboside triphosphate, a derivative of purine riboside, exhibits structural similarity to adenosine. This naturally occurring base analog possesses inhibitory effects on carcinogenic growth, particularly in cancer...
T12577	PTP1B-IN-3		Phosphatase
	PTP1B-IN-3 is a selective and potent PTP1B inhibitor with anticancer activity that inhibits PTP1B and TCPTP.PTP1B-IN-3 is used in the study of diabetes.		Phosphatase
T4256	PTP1B-IN-2		Phosphatase
	PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).		Phosphatase
T4340	SPI-112		Phosphatase
	SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2.		Phosphatase
T7356	PTP1B-IN-1	PTP1B inhibitor	Phosphatase
	PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)		Phosphatase
T40745	PTP1B-IN-13	PTP1B-IN-13
	PTP1B-IN-13, a potent and selective inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B), effectively targets the allosteric site, exhibiting an IC50 value of 1.59 μM.
T40835	PTP1B-IN-14	PTP1B-IN-14
	PTP1B-IN-14 is a selective inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) that targets the allosteric site, exhibiting an inhibitory concentration (IC50) value of 0.72 μM.
T22276	Bis(maltolato)oxovanadium(IV)	BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV)	Phosphatase , Others
	Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive and orally active pan-PTP (protein tyrosine phosphatases)inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent i...		Phosphatase , Others
T24073	PTP1B-IN-4	NUN 17724,PTP1B-inhibitor-2,PTP1B IN 2,PTP1B-IN-2,PTP1B-inhibitor-4,FRJ,PTP1B inhibitor 4,NUN17724,PTP1B inhibitor 2,PTP1BIN2,NUN-17724	Phosphatase
	PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes.		Phosphatase
T4491	LMPTP INHIBITOR 1 hydrochloride	LMPTP INHIBITOR 1 hydrochloride (1908414-82-3(free base))	Phosphatase
	LMPTP INHIBITOR 1 hydrochloride is a selective inhibitor of low molecular weight protein tyrosine phosphatase ( LMPTP ), with an IC 50 of 0.8 μM for LMPTP-A.		Phosphatase
T4081	MPTP hydrochloride	MPTP-hydrochloride	Apoptosis , Dopamine Receptor
	MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability. MPTP hydrochloride is toxic to dopaminergic neurons, which can lead to Parkinson's disease, and is widely used in th...		Apoptosis , Dopamine Receptor
T41298	LMPTP INHIBITOR 1 dihydrochloride		Phosphatase
	LMPTP Inhibitor 1 Dihydrochloride is a compound selectively targeting low molecular weight protein tyrosine phosphatase (LMPTP), exhibiting potent inhibitory activity with an IC50 value of 0.8 μM for LMPTP-A.		Phosphatase
T67893	PTP1B-IN-22		Phosphatase
	PTP1B-IN-22 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that inhibits glucose uptake in skeletal muscle L6 myotubes.		Phosphatase
T78702	PTP1B/AKR1B1-IN-1		Phosphatase
	PTP1B/AKR1B1-IN-1 is a dual inhibitor targeting protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), exhibiting inhibitory potency with IC50s of 0.06 μM for PTP1B and 4.3 μM for AKR1B1. Additionally, it...		Phosphatase
T63435	PTP1B-IN-16
	PTP1B-IN-16 is a promising and selective benzimidazole derivative and an inhibitor of protein tyrosine phosphatase 1B (PTP1B) (Ki: 12.6 μM).PTP1B-IN-16 can be used to study type 2 diabetes.
T61851	PTP1B-IN-3 diammonium
	PTP1B-IN-3 diammonium is a highly effective and orally bioavailable inhibitor of the protein tyrosine phosphatase 1B (PTP1B) enzyme, with an IC50 value of 120 nM for both PTP1B and TCPTP. This compound exhibits potent an...
T78703	PTP1B/AKR1B1-IN-2		Phosphatase
	PTP1B/AKR1B1-IN-2 (Compound 7f) is a potent inhibitor targeting both PTP1B and AKR1B1 with IC50 values of 3.2 and 2.1 μM, respectively, and K i values of 4.0 and 0.9 μM. This compound acts as an insulin mimetic and enhan...		Phosphatase
T71739	PTPMT1-IN-1
	PTPMT1-IN-1 is a PTEN-like mitochondrial phosphatase PTPMT1 inhibitor.
T63023	PTP1B-IN-19
	PTP1B-IN-19 (Compound 43) is a promising selective benzimidazole derivative as a protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 23.3 μM).PTP1B-IN-17 can be used to study type 2 diabetes.
T79479	MptpB-IN-2		Antibiotic
	MptpB-IN-2 (compound 20), a selective inhibitor for mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB), exhibits half maximal inhibitory concentrations (IC50) of 0.64 μM for MptpB, 4.06 μM for MptpA, and 4...		Antibiotic
T71195	MPTP-IN-22
	mPTP-IN-22 is a novel mitochondrial permeability transition pore (mptp) inhibitor
T74732	PROTAC PTPN2 degrader-1
	PROTAC PTPN2 Degrader-1 (compound example 77) is a potent entity capable of degrading PTPN2, showing promise for research applications in cancer or metabolic diseases [1].
T63022	PTP1B-IN-18
	PTP1B-IN-18 is an orally active, fully mixed protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 35.2 μM).PTP1B-IN-18 can be used to study type 2 diabetes.
T40216	PTPN22-IN-1	PTPN22-IN-1
	PTPN22-IN-1, detailed in WO2021007491A1 as compound L-1, is a potent PTPN22 inhibitor, demonstrating an IC50 of 1.4 μM and a Ki of 0.50 μM. This compound achieves over 7-10 fold selectivity against PTPN22 relative to com...
T73120	MptpB-IN-1
	MptpB-IN-1 is a potent, orally active MptpB inhibitor that targets the Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB), a secreted virulence factor evading host antimicrobial mechanisms. It effectively ...
T80544	PTPσ Inhibitor, ISP		Phosphatase
	PTPσ Inhibitor ISP is a compound that binds to recombinant human PTPs, thereby inhibiting PTPσ signaling. It has the capability to penetrate membranes and counteract the inhibitory effects of chondroitin sulfate proteogl...		Phosphatase
T79161	PROTAC PTPN2 degrader-2 TFA		Phosphatase
	PROTAC PTPN2 degrader-2 (example 187B) TFA is a potent degrader of Protein Tyrosine Phosphatase Non-receptor Type 2 (PTPN2), with potential applications in cancer and metabolic disease research [1].		Phosphatase
T79160	PROTAC PTPN2 degrader-2		Phosphatase
	PROTAC PTPN2 degrader-2 (example 187B) is a potent agent capable of degrading PTPN2, which holds potential for research in cancer and metabolic diseases [1].		Phosphatase
T63739	PTP1B-IN-15
	PTP1B-IN-15 is a potent and selective protein tyrosine phosphatase 1B (PTP1B) inhibitor that has shown research potential in type II diabetes and obesity.
T63021	PTP1B-IN-17
	PTP1B-IN-17 (Compound 45) is a selective benzimidazole derivative with potential as a protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 30.2 μM).PTP1B-IN-17 can be used in the study of type 2 diabetes.
T14841	BVT948		Phosphatase , P450 , Histone Methyltransferase
	BVT948 is a protein tyrosine phosphatase (PTP) inhibitor. It can also inhibit several CYP450 isoforms and lysine methyltransferase SETD8 (KMT5A).		Phosphatase , P450 , Histone Methyltransferase
T13176	TNO155	Batoprotafib	Phosphatase
	TNO155 is a protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11) inhibitor(IC50 : 0.011 µM),with potential antineoplastic activity.		Phosphatase
T16724	Razuprotafib	AKB-9778	Phosphatase , Others
	Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ß (HPTPß) inhibitor (IC50: 50 nM). Razuprotafib is effective for the activation of Tie-2 and is protective against acute kidney injury.		Phosphatase , Others
T10594	BpV(phen)		PTEN
	bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).		PTEN
T41370	(Rac)-RK-682
	(Rac)-RK-682 is a racemic mixture that functions as a protein tyrosine phosphatases (PTPases) inhibitor, specifically targeting protein tyrosine phosphatase 1B (PTP-1B), low molecular weight protein tyrosine phosphatases...
T82056	IP2
	IP2, an immunomodulatory agent, enhances PTP (Pioneer Translation Product)-derived antigen presentation in cancer cells without exhibiting cytotoxicity. Additionally, IP2 has been shown to induce tumor growth defects in ...
T79644	Antidiabetic agent 2		Glucosidase
	Compound 56 (Antidiabetic agent 2) is a glucose-uptake promoter that inhibits DPP-4, PTP-1B, α-amylase, and α-glucosidase, with IC50 values of 0.036, 0.042, 0.241, and 0.185 μM, respectively. This agent effectively decre...		Glucosidase
T73477	SHP844
	SHP844, a SHP2 inhibitor, exhibits an IC50 value of 18.9 µM. SHP2, a protein tyrosine phosphatase (PTP), plays a crucial role in modulating tyrosine phosphorylation levels, thereby influencing cell proliferation, differe...
T62442	MY33-3 hydrochloride
	MY33-3 hydrochloride is a potent and selective inhibitor of the protein tyrosine phosphatase RPTPβ/ζ (IC50~0.1 μM). MY33-3 hydrochloride inhibits PTP-1B (IC50~0.7 μM). MY33-3 hydrochloride reduces ethanol consumption and...
T74980	SPAA-52
	SPAA-52 is an orally active, competitive and reversible low-molecular-weight protein tyrosine phosphatase ( LMW-PTP ) inhibitor ( IC 50 =4 nM, K i =1.2 nM). SPAA-52 can be used in diabete research [1] .
T39677	MY33-3	MY33-3
	MY33-3 is a powerful and specific inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, demonstrating an IC50 value of approximately 0.1 μM. Moreover, MY33-3 exhibits inhibitory activity against PTP-1B with an IC...
T28901	T-2007	5,5-Diphenylbarbituric acid,DPB
	T-2007 is an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist and gamma-aminobutyric acid (GABA) receptor agonist. T2007 and its analogs upregulates CYP3A4 and MDR1. T-2007 depressed both t...

Compounds

PTP inhibitor 1

T7541

Synonym: PTP Inhibitor II

Cyt-PTPε Inhibitor-1

T10927

Synonym: Cyt-PTP|A Inhibitor-1

Target: Phosphatase, Src

SF1670

T6667

Synonym: PTP CD45 Inhibitor,PTPase CD45 Inhibitor

Target: Phosphatase, PTEN, Autophagy

2-Bromo-4'-hydroxyacetophenone

T7084

Synonym: SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide

Target: Phosphatase, PPAR

Purine riboside triphosphate

T39856

Synonym: PTP,Purine riboside triphosphate

Synonym: PTP1B inhibitor

Target: Phosphatase

PTP1B-IN-13

T40745

Synonym: PTP1B-IN-13

Target:

PTP1B-IN-14

T40835

Synonym: PTP1B-IN-14

Target:

Bis(maltolato)oxovanadium(IV)

T22276

Synonym: BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV)

Target: Phosphatase, Others

PTP1B-IN-4

T24073

Synonym: NUN 17724,PTP1B-inhibitor-2,PTP1B IN 2,PTP1B-IN-2,PTP1B-inhibitor-4,FRJ,PTP1B inhibitor 4,NUN17724,PTP1B inhibitor 2,PTP1BIN2,NUN-17724

Target: Phosphatase

LMPTP INHIBITOR 1 hydrochloride

T4491

Synonym: LMPTP INHIBITOR 1 hydrochloride (1908414-82-3(free base))

Target: Phosphatase

MPTP hydrochloride

T4081

Synonym: MPTP-hydrochloride

Target: Apoptosis, Dopamine Receptor

LMPTP INHIBITOR 1 dihydrochloride

PTP1B-IN-3 diammonium

PROTAC PTPN2 degrader-1

Synonym: PTPN22-IN-1

PTPσ Inhibitor, ISP

T80544

Synonym:

Target: Phosphatase

PROTAC PTPN2 degrader-2 TFA

T79161

Synonym:

Target: Phosphatase

PROTAC PTPN2 degrader-2

Target: Phosphatase, P450, Histone Methyltransferase

TNO155

T13176

Synonym: Batoprotafib

Target: Phosphatase, Others

Synonym: 5,5-Diphenylbarbituric acid,DPB

Target:

Cat No.	Product Name	Synonyms	Targets
T73073	PTP1B-IN-21
	PTP1B-IN-21 is a compound that functions as a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC50=1.56 μM), demonstrating a marked preference over the structurally similar T-cell protein tyrosine phosphat...
T73072	PTP1B-IN-20
	PTP1B-IN-20 is a selective PTP1B (protein tyrosine phosphatase 1B) inhibitor, exhibiting an IC50 of 1.05 μM, and demonstrates selectivity over TCPTP (T-cell protein tyrosine phosphatase), which has an IC50 of 78.0 μM. Th...
T39219	Ficusonolide
	Ficusonolide exhibits significant antidiabetic activity through its interactions with dipeptidyl peptidase-IV (DPP-IV), protein tyrosine phosphatase 1B (PTP-1B), α-glucosidase, and α-amylase.
T3930	Taraxerol acetate	Taraxeryl acetate	Phosphatase , HSV
	Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. A. roxburghiana has antidiabetic activ...		Phosphatase , HSV

Natural Products

Synonym: Taraxeryl acetate

Target: Phosphatase, HSV

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02511	PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST)	Human	Baculovirus Insect Cells
	PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways. The higher PTPRA level was associated with worse prognosis of SCC patients and PTP...
TMPJ-00908	LMW-PTP Protein, Human, Recombinant (His)	Human	E. coli
	Low Molecular Weight Phosphotyrosine Protein Phosphatase (LMW-PTP) is a member of the low molecular weight phosphotyrosine protein phosphatase family. LMW-PTP serves as an acid phosphatase and a protein tyrosine phosphat...
TMPY-03484	TCPTP Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	TCPTP Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 36.8 kDa and the accession number is P17706-1.
TMPK-01132	PRL-1/PTP4A1 Protein, Human, Recombinant (His)	Human	E. coli
	Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PRL-1 (PTP4A1) is ...
TMPY-03548	PTPN12 Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	PTPN12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.8 kDa and the accession number is AAA36529.1.
TMPY-03486	PTPN12 Protein, Human, Recombinant (aa 1-355, His & GST)	Human	Baculovirus Insect Cells
	PTPN12 Protein, Human, Recombinant (aa 1-355, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.4 kDa and the accession number is AAA36529.1.
TMPY-02369	TCPTP Protein, Mouse, Recombinant (aa 2-314, His)	Mouse	Baculovirus Insect Cells
	TCPTP Protein, Mouse, Recombinant (aa 2-314, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 38.7 kDa and the accession number is Q06180-1.
TMPJ-01139	IA2 Protein, Human, Recombinant (aa 576-950, His)	Human	E. coli
	IA2 Protein, Human, Recombinant (aa 576-950, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50 KDa and the accession number is Q16849.
TMPJ-01141	IA2 Protein, Human, Recombinant (aa 687-979, His)	Human	E. coli
	IA2 Protein, Human, Recombinant (aa 687-979, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is Q16849.
TMPY-02173	TCPTP Protein, Human, Recombinant (aa 1-314, His & GST)	Human	Baculovirus Insect Cells
	TCPTP Protein, Human, Recombinant (aa 1-314, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 64.4 kDa and the accession number is P17706-1.
TMPJ-01140	IA2 Protein, Human, Recombinant (aa 607-686 & aa 795-888 , His)	Human	E. coli
	IA2 Protein, Human, Recombinant (aa 607-686 & aa 795-888 , His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26-30 KDa and the accession number is Q16849.
TMPY-02386	PTP4A2 Protein, Human, Recombinant (GST)	Human	E. coli
	PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PR...
TMPY-02763	DEP-1 Protein, Human, Recombinant (aa 997-1337, His)	Human	E. coli
	DEP1 / PTPRJ (Receptor-type tyrosine-protein phosphatase eta) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, includin...
TMPY-05474	REG1A Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	REG1A Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number is P05451.
TMPY-01335	REG1A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	REG1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number is P05451.
TMPJ-00465	PTP1C Protein, Human, Recombinant (His)	Human	E. coli
	Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mi...
TMPJ-00053	PRL-2 Protein, Human, Recombinant (His)	Human	E. coli
	PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational ...
TMPY-04125	PTP1B Protein, Human, Recombinant (His)	Human	E. coli
	PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c...
TMPY-00487	PTPN9 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Protein tyrosine phosphatase non-receptor type 9 (PTPN9), also named PTP-MEG2, is an important member of the protein tyrosine phosphatase family that is involved in variety of human diseases.PTPN9 plays an important role...
TMPY-02602	PTPMT1 Protein, Human, Recombinant (His)	Human	E. coli
	PTPMT1 (PTP localized to the Mitochondrion 1) is a member of the protein tyrosine phosphatase superfamily that is localized exclusively to the mitochondrion. It has been recently reported that PTPMT1 dephosphorylates pho...
TMPK-00742	PRL-3/PTP4A3 Protein, Human, Recombinant (His)	Human	E. coli
	Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PTP4A3 (PRL-3) pla...
TMPH-02987	PTPRS Protein, Mus musculus, Recombinant (His & Myc)	Mouse	Baculovirus Insect Cells
	PTPRS Protein, Mus musculus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 35.8 kDa and the accession number is B0V2N1.
TMPH-02278	PTPN5 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors. PTPN5 Protein, Human, Recombinant (His & SUMO) i...
TMPH-02012	PTPRZ1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	PTPRZ1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-02010	PTPRB Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	PTPRB Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-02013	PTPRZ1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligo...
TMPH-02011	PTPRB Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	PTPRB Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02277	PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)	Human	E. coli
	Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosph...
TMPH-02878	PTPRS Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects...
TMPY-02595	DUSP14 Protein, Human, Recombinant (His & MBP)	Human	E. coli
	Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosph...
TMPY-02131	Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST)	Human	E. coli
	The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of im...
TMPY-03296	SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)	Mouse	Baculovirus Insect Cells
	PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and onco...
TMPY-03125	SHP-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase(PTP) family, non-receptor class 2 subfamily. PTPs catalyze the removal of phosphate groups from tyrosine residues by the hydrolysis of phosphoric ac...