store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 153.00 | |
1 mg | 35 days | $ 280.00 | |
5 mg | 35 days | $ 660.00 | |
10 mg | 35 days | $ 1,170.00 |
Description | PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes. |
Targets&IC50 | PTP1B:8 μM (IC50) |
In vitro | In CHO cells overexpressing human IR, PTP1B-IN-4 (250 µM) stimulates the phosphorylation of insulin receptors. PTP1B-IN-4 induces phosphorylation of IRS-1 and Akt which are proteins downstream of the insulin receptor[3]. |
Synonyms | NUN 17724, PTP1B-inhibitor-2, PTP1B IN 2, PTP1B-IN-2, PTP1B-inhibitor-4, FRJ, PTP1B inhibitor 4, NUN17724, PTP1B inhibitor 2, PTP1BIN2, NUN-17724 |
Molecular Weight | 741.45 |
Formula | C26H19Br2N3O7S3 |
CAS No. | 765317-72-4 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (121.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PTP1B-IN-4 765317-72-4 Metabolism Phosphatase NUN 17724 PTP1B-inhibitor-2 PTP1B IN 2 PTP1B-IN-2 PTP1B-inhibitor-4 FRJ PTP1B inhibitor 4 NUN17724 PTP1B inhibitor 2 PTP1BIN2 NUN-17724 inhibitor inhibit