solid — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T20019	Malachite green	Solid Green O,Solid Green Crystals O	Others
	Malachite green (Solid Green Crystals O) is an N-methylated diaminotriphenylmethane dye used for coloring.		Others
T6796	CB-5083	CB5083,CB 5083	p97
	CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).		p97
T9050	AG-270		Others , Methionine Adenosyltransferase (MAT)
	AG-270 is an allosteric and orally active inhibitor of MAT2A.		Others , Methionine Adenosyltransferase (MAT)
T19278	Dicaprylyl carbonate	Dimethyl carbonate	Others
	Dicaprylyl carbonate (Dimethyl carbonate) is a solid fat derived from plants and a dry emollient. Dimethyl carbonate has good skin compatibility and comprehensive properties, such as a sunscreen filter with the ability t...		Others
T9705	TL-895		BTK
	TL-895 is an ATP-competitive, and highly selective irreversible inhibitor of Bruton’s Tyrosine Kinase(BTK). TL-895 showed good potency with an IC50 of 1.5 nM and a Ki of 11.9 nM.		BTK
T12695	RBN-2397		PARP
	RBN-2397 is a potent, selective and orally active accross species NAD+ competitive PARP7 inhibitor with IC50 less than 3 nM.		PARP
T7318	Elimusertib	BAY-1895344	ATM/ATR
	Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.Elimusertib shows potent anti-tumor efficacy in monotherapy and strong combination potential with the target...		ATM/ATR
T9430	Venadaparib	NOV140101,IDX-1197	PARP
	Venadaparib (NOV140101) (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib is insensitive to PARP-5. Venadaparib prevents the...		PARP
T3124	Carbendazim	Bavistin,Carbendazole,Mercarzole	Antifungal
	Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspec...		Antifungal
T9756	AZD-9574		PARP
	AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and advanced solid malignancies.		PARP
T13044	Mevociclib	SY-1365	CDK
	Mevociclib (SY-1365) is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors.		CDK
T8327	ONO-7475		Trk receptor , TAM Receptor
	ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase		Trk receptor , TAM Receptor
T28475	Pyrazoloacridine	PD-115934,NSC 366140,NSC-366140,PD 115,934,PD 115934	Apoptosis , Topoisomerase
	Pyrazoloacridine (PD 115934) is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 μM in K562 cells. Pyrazoloacridine shows anti-cancer activity.		Apoptosis , Topoisomerase
T2325	Neratinib	HKI-272	EGFR , HER
	Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.		EGFR , HER
T6079	NVP-ADW742	ADW742,ADW,GSK 552602A	Apoptosis , IGF-1R
	NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.		Apoptosis , IGF-1R
T2134	Dorzolamide hydrochloride	MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,Dorzolamide HCl	Carbonic Anhydrase
	Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water ...		Carbonic Anhydrase
TN1035	Irisolidone		IL Receptor , NF-κB , Chloride channel
	Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.		IL Receptor , NF-κB , Chloride channel
T124039	Achalensolide
	Achalensolide is a useful organic compound for research related to life sciences. The catalog number is T124039 and the CAS number is 87302-42-9.
TL0014	Pinusolide		ERK , p38 MAPK , Calcium Channel , Lipoxygenase , PAFR , Caspase , JNK , AMPK
	Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, and could be used to treat neurodegenerative diseases. Pinus...
TN2641	15-Methoxypinusolidic acid		ERK , IL Receptor , p38 MAPK , Calcium Channel , NOS , NF-κB , COX , JNK , NMDAR , PPAR
	15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methoxypinusolidic acid suppresses adipocyte differentiation thro...