Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.
Description | Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM. |
In vivo | Irisolidone may attenuate ethanol-induced gastritis by inhibiting the infiltration of immune cells, particularly neutrophils, through the regulation of CXCL-4 or IL-8 secretion[2]. |
Synonyms | 葛花苷元, 尼泊尔鸢尾异黄酮 |
Molecular Weight | 314.29 |
Formula | C17H14O6 |
CAS No. | 2345-17-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 10 mM
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Irisolidone 2345-17-7 NF-Kb信号通路 离子通道 免疫与炎症 IL Receptor NF-κB Chloride channel Chloride Channel Cl? Channels Inhibitor hepatoprotective inhibit VRAC inhibitor