Powder: -20°C for 3 years | In solvent: -80°C for 1 year
15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methoxypinusolidic acid suppresses adipocyte differentiation through the inhibition of PPARgamma-dependent adipogenic gene expression.15-Methoxypinusolidic acid attenuates glutamate-induced excitotoxicity via stabilization of [Ca2+]i homeostasis and suppression of oxidative stress possibly through the actions on the NMDA receptors.15-Methoxypinusolidic acid induced apoptosis in murine microglial cells, presumably via inhibition of the cell cycle progression.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 670.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 690.00 |
Description | 15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methoxypinusolidic acid suppresses adipocyte differentiation through the inhibition of PPARgamma-dependent adipogenic gene expression.15-Methoxypinusolidic acid attenuates glutamate-induced excitotoxicity via stabilization of [Ca2+]i homeostasis and suppression of oxidative stress possibly through the actions on the NMDA receptors.15-Methoxypinusolidic acid induced apoptosis in murine microglial cells, presumably via inhibition of the cell cycle progression. |
Source |
Molecular Weight | 362.46 |
Formula | C21H30O5 |
CAS No. | 769928-72-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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15-Methoxypinusolidic acid 769928-72-5 DNA Damage/DNA Repair Immunology/Inflammation MAPK Membrane transporter/Ion channel Metabolism Neuroscience NF-Κb ERK IL Receptor Calcium Channel p38 MAPK COX NOS NF-κB NMDAR PPAR JNK 15Methoxypinusolidic acid 15 Methoxypinusolidic acid inhibitor inhibit