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15-Methoxypinusolidic acid

Catalog No. TN2641 CAS 769928-72-5

15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methoxypinusolidic acid suppresses adipocyte differentiation through the inhibition of PPARgamma-dependent adipogenic gene expression.15-Methoxypinusolidic acid attenuates glutamate-induced excitotoxicity via stabilization of [Ca2+]i homeostasis and suppression of oxidative stress possibly through the actions on the NMDA receptors.15-Methoxypinusolidic acid induced Apoptosis in murine microglial cells, presumably via inhibition of the cell cycle progression.

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15-Methoxypinusolidic acid, CAS 769928-72-5

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Purity: 98%

Biological Description

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Description

15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methoxypinusolidic acid suppresses adipocyte differentiation through the inhibition of PPARgamma-dependent adipogenic gene expression.15-Methoxypinusolidic acid attenuates glutamate-induced excitotoxicity via stabilization of [Ca2+]i homeostasis and suppression of oxidative stress possibly through the actions on the NMDA receptors.15-Methoxypinusolidic acid induced apoptosis in murine microglial cells, presumably via inhibition of the cell cycle progression.

Molecular Weight	362.46
Formula	C21H30O5
CAS No.	769928-72-5

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Powder: -20°C for 3 years

In solvent: -80°C for 2 years

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Keywords

15-Methoxypinusolidic acid 769928-72-5 DNA Damage/DNA Repair Immunology/Inflammation MAPK Membrane transporter/Ion channel Metabolism Neuroscience NF-Κb JNK NMDAR PPAR Calcium Channel NOS NF-κB ERK IL Receptor p38 MAPK COX 15Methoxypinusolidic acid 15 Methoxypinusolidic acid Inhibitor inhibitor inhibit

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