a-b — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5680	Aloin(mixture of A&B)		MMP , IL Receptor , Antibacterial , Antifungal
	ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.		MMP , IL Receptor , Antibacterial , Antifungal
T26423	A 58365 B	A-58365 B,A58365 B
	A 58365 B, an angiotensin converting enzyme (ACE) inhibitor isolated from Streptomyces chromofuscus, is used for the treatment of congestive heart failure and hypertension.
T2742	Aloin	Barbaloin,Barbalin,Aloin-A,Aloin(mixture of A&B),Barbaloin-A	Tyrosinase
	Aloin (Aloin-A)(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.		Tyrosinase
TN3628	Chamaejasmenin B		Others
	Chamaejasmenin B is a compound isolated from Stellera chamaejasme L. Chamaejasmenin B has anticancer and antitumor activity, inhibiting cancer cell migration and invasion, and inhibiting tumor metastasis.Chamaejasmenin B...		Others
T3899	Calceolarioside B	Desrhamnosyl isoacteoside,Nuomioside A	Aromatase
	Calceolarioside B (Desrhamnosyl isoacteoside) displays inhibition of aromatase. Calceolarioside B displays inhibition of human recombinant PKCalpha.		Aromatase
TN2211	Silybin B	Silibinin B	Apoptosis , Beta Amyloid , Bcr-Abl
	Silybin B (Silibinin B) is an effective inhibitor of raloxifene 4 '- and 6-glucosalylation, an effective anti-fibrinogenic and anti-oligomeric component of Silymarin, with free radical scavenging activity of 1, 1-dipheny...		Apoptosis , Beta Amyloid , Bcr-Abl
T14072	A-443654		ERK , VEGFR , GSK-3 , FLT , Casein Kinase , MAPK , Akt , PKA , Chk , CDK , Src , PKC , S6 Kinase
	A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).
T6139	A-674563	A674563	ERK , GSK-3 , Akt , PKA , CDK
	A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.		ERK , GSK-3 , Akt , PKA , CDK
TN4970	Sculponeatin B		Others
	Sculponeatin A is a natural product from Rabdosia amethystoides.		Others
T5S0896	Loureirin A		Akt , PI3K
	Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related pept...		Akt , PI3K
T6S1917	Schisandrol B	Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B	P450 , Reactive Oxygen Species , Autophagy
	1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...		P450 , Reactive Oxygen Species , Autophagy
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
T3S2325	Ardisiacrispin A	Saxifragifolin B,LTS-4,Deglucocyclamin	HSV
	Ardisiacrispin A (Deglucocyclamin) has cytotoxic activity toward HepG2 cancer cell with the GI(50) value of 1.56μM, it could inhibit the proliferation of Bel-7402 cells by inducing apoptosis and disassembling microtubule...		HSV
TN2357	Iristectorigenin A		Others
	Iristectorigenin A is a natural isoflavone isolated from B. chinensis rhizomes with antioxidant activity.		Others
TN6782	Oroxylin A 7-O-β-d-glucuronide		Others
	Oroxylin A 7-O-β-d-glucuronide was a new alkaloid which found in the bulbs of Lycoris radiata.		Others
T3910	Pulchinenoside C	Anemoside B4,Chinensioside A,Pulchinenoside B4,Pulsatilla saponin B4	IL Receptor
	Pulchinenoside C (Anemoside B4) is an abundant triterpenoid saponin isolated from P. chinensis and exerts anti-inflammatory and antioxidant effects.		IL Receptor
T3871	Daucosterol	Alexandrin,Sitogluside,β-Sitosterol β-D-glucoside,Eleutheroside A	Glucosidase
	Daucosterol (Sitogluside) has proliferation-enhancing activity, may be involved in the IGF1-AKT pathway. Daucosterol(β-Sitosterol β-D-glucoside) has efficient and inexpensive neuroprotectant effect, to contribute to IGF1...		Glucosidase
T3395	Timosaponin AIII	Filiferin B,AneMarsaponin A3,Timosaponin A3	AChE , mTOR
	Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC...		AChE , mTOR
T6S2115	Ginkgolide J	BN 52024,7-beta-Hydroxyginkgolide A	PDE
	Ginkgolide J (BN 52024) has neuroprotective activity, it can prevent A beta(1-42) induced inhibition of long-term potentiation in the CA1 region of mouse hippocampal slices.		PDE
TN1115	Pseudolaric acid A-O-β-D-glucopyranoside	Pseudolaric acid A-O-beta-D-glucopyranoside	Others
	Pseudolaric acid A-O-β-D-glucopyranoside (Pseudolaric acid A-O-beta-D-glucopyranoside) is a natural product with antibacterial, anticancer		Others