Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aloin (Aloin-A)(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 45.00 | |
100 mg | In stock | $ 55.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Aloin (Aloin-A)(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor. |
In vivo | In the MCF-7 cell line, Aloin induces apoptosis and decreases the proportion of cells in mitosis by inhibiting the expression of Topoisomerase IIα and downregulating Cyclin B1. In HeLaS3 cells, Aloin exhibits significant antiproliferative effects at physiological concentrations (IC50=97 μM), leading to cell cycle arrest in the S phase and a marked increase in apoptosis. |
Source |
Synonyms | Barbaloin, Barbalin, Aloin-A, Aloin(mixture of A&B), Barbaloin-A |
Molecular Weight | 418.39 |
Formula | C21H22O9 |
CAS No. | 1415-73-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 2 mg/mL (4.78 mM)
H2O: 1 mg/mL (2.39 mM)
DMSO: 4.18 mg/mL (10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Aloin 1415-73-2 Proteases/Proteasome Tyrosinase Barbaloin inhibit Inhibitor Barbalin Aloin-A Aloin(mixture of A&B) Barbaloin-A inhibitor