store at low temperture,keep away from direct sunlight
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Silybin B and silybin A are potent inhibitors of both raloxifene 4'- and 6-glucuronidation in all enzyme systems; they show strong effects on cell growth inhibition and <a href="/pathway/Apoptosis" style="display: inline; color: #c13a36">Apoptosis</a> induction in human chronic myeloid leukemia K562 cells. Silybin B exhibits 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | Inquiry | $ 120.00 | |
5 mg | Inquiry | $ 580.00 |
Description | Silybin B and silybin A are potent inhibitors of both raloxifene 4'- and 6-glucuronidation in all enzyme systems; they show strong effects on cell growth inhibition and apoptosis induction in human chronic myeloid leukemia K562 cells. Silybin B exhibits 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity. |
In vitro | The present study assessed the effects of the diastereoisomers on cell apoptosis, and compared these with their mixture, silybin, in human chronic myeloid leukemia K562 cells. Both isomers showed stronger effects on cell growth inhibition and apoptosis induction than silybin. Compared with Silybin B, silybin A showed higher effects on the production of intracellular reactive oxygen species and Ca2+. |
Synonyms | Silibinin B |
Molecular Weight | 482.44 |
Formula | C25H22O10 |
CAS No. | 142797-34-0 |
store at low temperture,keep away from direct sunlight
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 225.0 mg/mL (466.4 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Silybin B 142797-34-0 Angiogenesis Tyrosine Kinase/Adaptors Apoptosis Cytoskeletal Signaling Neuroscience Beta Amyloid Bcr-Abl Silibinin B Inhibitor inhibitor inhibit