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Loureirin A

Catalog No. T5S0896 CAS 119425-89-7

Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related peptide (CRP), ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs.

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Loureirin A, CAS 119425-89-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 68.00
5 mg	In stock	$ 147.00
10 mg	In stock	$ 218.00
25 mg	In stock	$ 369.00
50 mg	In stock	$ 543.00
100 mg	In stock	$ 776.00
500 mg	In stock	$ 1,570.00
1 mL * 10 mM (in DMSO)	In stock	$ 218.00

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Purity: 99.84%

Purity: 99.83%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Source

Natural Products > Liliaceae > Dracaena

Molecular Weight	286.32
Formula	C17H18O4
CAS No.	119425-89-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 86.6 mg/mL (302.46 mM)

References and Literature

1. Hao H Z, He A D, Wang D C, et al. Antiplatelet activity of loureirin A by attenuating Akt phosphorylation: In vitro studies[J]. European Journal of Pharmacology, 2015, 746:63-69.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Traditional Chinese Medicine Monomer Library Kinase Inhibitor Library Cytoskeletal Signaling Pathway Compound Library Anti-Tumor Natural Product Library Selected Plant-Sourced Compound Library Autophagy Compound Library Anti-Aging Compound Library Flavonoid Natural Product Library NO PAINS Compound Library

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Keywords

Loureirin A 119425-89-7 Cytoskeletal Signaling PI3K/Akt/mTOR signaling Akt PI3K PKB Protein kinase B Inhibitor inhibit inhibitor

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