Search Result

Search Results for " 1e "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T22288	(1E)-CFI-400437 dihydrochloride	CFI-400437 dihydrochloride	PLK
	(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.		PLK
T66121	Ketoconazole Intermediate 1e	(cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate	Others
	Ketoconazole Intermediate 1e ((cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4- methylbenzenesulfonate) is a ketoconazole intermediate.		Others
TP1531	Guangxitoxin 1E
	Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.
T50029	2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine	2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine	Others
	2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine (2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine) is a heterocyclic compound. It inhibits monoamine oxidase, resulting in elevated monoamine levels in the body. It can...		Others
T8871	C/EBPα inducer 1	4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-	Others
	C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation via upregulation of C/EBP.		Others
T9320	YK-3-237	B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid	Sirtuin
	YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferative effects toward triple-negative breast cancer (TNBC) cells ca...		Sirtuin
T82816	Brevinin-1E
	Brevinin-1E, an antimicrobial peptide, originates from the skin secretions of the Rana esculenta (European green frog) [1].
T8055	TFEB activator 1	(1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,,Curcumin analog compound C1,Curcumin analog C1,RPN77612	Others , Autophagy
	TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer's disease.		Others , Autophagy
T9105	NF-κB-IN-1	1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-	IκB/IKK , NF-κB
	NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 dir...		IκB/IKK , NF-κB
T7205	A-967079		TRP/TRPV Channel
	A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 values of 67 and 289 nM for the human and rat isoforms, respectively.		TRP/TRPV Channel
T2280	Endoxifen (Z-isomer)	Endoxifen Z-isomer	Estrogen Receptor/ERR , EGFR , Potassium Channel , Estrogen/progestogen Receptor , HER
	Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptors that also inhibits aromatase activity.
T7493	AG-13958	AG-013958	VEGFR
	AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.		VEGFR
T36401	DCVC
	DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.Target: TNF-αin vitro: DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 μM) significantly inhib...
T3166	VX-11e	Vertex-11e,VTX-11e,TCS ERK 11e	ERK , GSK-3 , FLT , CDK , Aurora Kinase
	VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.		ERK , GSK-3 , FLT , CDK , Aurora Kinase
T35529	HSMG-1 inhibitor 11e		Others
	hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment.		Others
T125237	TMC 151E

T82815	Brevinin-1Ea
	Brevinin-1Ea, an antimicrobial peptide, originates from the skin secretions of the European green frog (Rana esculenta) [1].
T76244	Amp1EP9
	Amp1EP9, an antimicrobial peptide, serves as a potent and non-toxic candidate for the development of effective antimicrobial agents. It holds promise for research into multidrug-resistant bacterial infections [1].
T82007	JH-131e-153
	JH-131e-153, a diacylglycerol (DAG)-lactone, serves as a small molecule activator for the C1 domain of Munc13-1, exhibiting an activation hierarchy of WT>I590≈R592A≈W588A. This compound’s C1 domain shares homology in seq...
T70441	1E7-03
	1E7-03 is an inhibitor of HIV-1 transcription, by targeting host Protein Phosphatase-1 (PP1).
T126263	14,15-Dinorcleroda-3,11E-dien-13-one
	14,15-Dinorcleroda-3,11E-dien-13-one is a useful organic compound for research related to life sciences and the catalog number is T126263.
T78143	(R)-VX-11e		ERK
	'(R)-VX-11e (Compound 1) functions as an inhibitor of ERK2 [1].'		ERK
T35182	Xinidamine	BRN 0891979,Xinidaminum,Xinidamino
	Xinidamine (BRN 0891979) has antitumor activity and can be used to study benign prostatic hyperplasia, macular degeneration and prostatic intraepithelial neoplasia .Xinidamine inhibits the proliferation of PWR-1E cells w...
T67775	Enpp/Carbonic anhydrase-IN-1		PDE , Carbonic Anhydrase
	Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase. Enpp/Carbonic anhydrase-IN-1 exhibits IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 µM for NPP1, NPP2, NPP3, CA-II, CA-IX respectiv...		PDE , Carbonic Anhydrase
T80893	Urease-IN-9
	Urease-IN-9 (Compound 1e), an urease inhibitor with an IC50 of 19.5 μM, effectively impedes the enzyme's activity [1].
T60791	Antitubercular agent-11
	Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].
T60481	GABAA receptor agent 4
	GABAA receptor agent 4 (compound 1e) is a potent antagonist of γ-GABAAR with Ki of 0.18 µM. GABAA receptor agent 4 has immunomodulatory potential which was shown to efficiently rescue the inhibition of T cell proliferati...
T16865	SCH28080		ATPase , Proton pump
	SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent inhibitor of acid secretion in vivo with anti-ulcer activity, an...		ATPase , Proton pump
T83137	ALP/Carbonic anhydrase-IN-1		Carbonic Anhydrase
	Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline phosphatase (ALP). It exhibits inhibitory IC50 values of 0....		Carbonic Anhydrase
T72194	KCa1.1 channel activator-1
	KCa1.1 Channel Activator-1, a hybrid derivative of Quercetin, selectively stimulates the vascular KCa1.1 channels while also blocking CaV1.2 channels. Additionally, it demonstrates weak myorelaxant activity.

Compounds

(1E)-CFI-400437 dihydrochloride

T22288

Synonym: CFI-400437 dihydrochloride

Target: PLK

Ketoconazole Intermediate 1e

T66121

Synonym: (cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate

2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine

T50029

Synonym: 2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine

Target: Others

C/EBPα inducer 1

T8871

Synonym: 4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-

Target: Others

YK-3-237

T9320

Synonym: B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid

Synonym: (1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,,Curcumin analog compound C1,Curcumin analog C1,RPN77612

Target: Others, Autophagy

NF-κB-IN-1

T9105

Synonym: 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-

Target: IκB/IKK, NF-κB

A-967079

T7205

Synonym:

Target: TRP/TRPV Channel

Endoxifen (Z-isomer)

T2280

Synonym: Endoxifen Z-isomer

Target: Estrogen Receptor/ERR, EGFR, Potassium Channel, Estrogen/progestogen Receptor, HER

Synonym: Vertex-11e,VTX-11e,TCS ERK 11e

Target: ERK, GSK-3, FLT, CDK, Aurora Kinase

14,15-Dinorcleroda-3,11E-dien-13-one

Synonym: BRN 0891979,Xinidaminum,Xinidamino

Target:

Enpp/Carbonic anhydrase-IN-1

T67775

Synonym:

Target: PDE, Carbonic Anhydrase

Antitubercular agent-11

T60791

Synonym:

Target:

GABAA receptor agent 4

Target: ATPase, Proton pump

ALP/Carbonic anhydrase-IN-1

T83137

Synonym:

Target: Carbonic Anhydrase

KCa1.1 channel activator-1

T72194

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T6S1688	(1E,6E)-Bis(demethoxy)curcumin	Curcumin III,Didemethoxycurcumin,BDMC	Apoptosis , Others , Autophagy
	(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.		Apoptosis , Others , Autophagy
TN6492	(1E)-3-methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one
	(1E)-3-methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one is a natural product for research related to life sciences. The catalog number is TN6492 and the CAS number is 1393342-06-7.
T7792	Hispidin		Endogenous Metabolite , PKC
	Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties		Endogenous Metabolite , PKC
TN5839	Ethyl (9Z,11E)-13-hydroxyoctadeca-9,11-dienoate
	Ethyl (9Z,11E)-13-hydroxyoctadeca-9,11-dienoate is a natural product for research related to life sciences. The catalog number is TN5839 and the CAS number is 947529-92-2.
T17302	(9Z,11E)-Prodlure	(9Z,11E)-Prodlure,Litlure A,(9Z,11E)-Tetradecadien-1-yl acetate,Ferodin SL	Others
	(9Z, 11E) - Prodlure is the main component of the sex pheromone of female Spodoptera littoralis.		Others
T10044	13-Oxo-9E,11E-octadecadienoic acid		PPAR
	13-Oxo-9E,11E-octadecadienoic acid, a potent PPARα activator derived from tomato juice and an isomer of 9-oxo-ODA, exhibits the ability to decrease plasma and hepatic triglyceride levels in obese diabetic mice[1].		PPAR
TN5848	Methyl (9Z,11E)-13-hydroxyoctadeca-9,11-dienoate
	Methyl (9Z,11E)-13-hydroxyoctadeca-9,11-dienoate is a natural product for research related to life sciences. The catalog number is TN5848 and the CAS number is 109837-85-6.
TN6470	(3E,5E,11E)-tridecatriene-7,9-diyne-1,2-diacetate
	(3E,5E,11E)-tridecatriene-7,9-diyne-1,2-dacetate can be used in related research in the field of life sciences, and its product number is TN6470.
TN2506	(1,5E,11E)-tridecatriene-7,9-diyne-3,4-diacetate		Others
	(1,5E,11E)-tridecatriene-7,9-diyne-3,4-diacetate is a natural product for research related to life sciences. The catalog number is TN2506 and the CAS number is 201012-14-8.		Others
TJS0341	7-Amino-4-(trifluoromethyl)coumarin	Coumarin 151,AFC	5-HT Receptor
	7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a Galanin Receptor 2 (GALR2) antagonist. 7-Amino-4-(trifluorometh...		5-HT Receptor

Natural Products

(1E,6E)-Bis(demethoxy)curcumin

T6S1688

Synonym: Curcumin III,Didemethoxycurcumin,BDMC

Target: Apoptosis, Others, Autophagy

(1E)-3-methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one

Target: Endogenous Metabolite, PKC

Ethyl (9Z,11E)-13-hydroxyoctadeca-9,11-dienoate

Synonym: (9Z,11E)-Prodlure,Litlure A,(9Z,11E)-Tetradecadien-1-yl acetate,Ferodin SL

Target: Others

13-Oxo-9E,11E-octadecadienoic acid

T10044

Synonym:

Target: PPAR

Methyl (9Z,11E)-13-hydroxyoctadeca-9,11-dienoate

TN5848

Synonym:

Target:

(3E,5E,11E)-tridecatriene-7,9-diyne-1,2-diacetate

TN6470

Synonym:

Target:

(1,5E,11E)-tridecatriene-7,9-diyne-3,4-diacetate

TN2506

Synonym:

Target: Others

7-Amino-4-(trifluoromethyl)coumarin

TJS0341

Synonym: Coumarin 151,AFC

Target: 5-HT Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02879	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158)	Human	E. coli
	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158) is expressed in E. coli expression system. The predicted molecular weight is 17.2 kDa and the accession number is Q9UHA7.
TMPY-01660	SULT1E1 Protein, Human, Recombinant (His)	Human	E. coli
	Estrogen sulfotransferase, also known as Sulfotransferase, estrogen-preferring, Sulfotransferase 1E1, SULT1E1 and ST1E1, is a cytoplasm enzyme that belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catal...
TMPY-00193	ULBP-4 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The expressions of both RAET1E2 transcripts and protein can be found in different tumor cells and tissues. ULBP-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molec...
TMPY-00194	ULBP-4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The expressions of both RAET1E2 transcripts and protein can be found in different tumor cells and tissues. ULBP-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molec...
TMPY-02818	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (His)	Human	E. coli
	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 19.2 kDa and the accession number is Q9UHA7.
TMPY-03976	EEF1E1 Protein, Human, Recombinant (His)	Human	E. coli
	EEF1E1, also known as AIMP3 and p18, is a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, EEF1E1 is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex...
TMPY-02855	CD1E & B2M Heterodimer Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CD1E & B2M Heterodimer Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.5 kDa and the accession number is EHH50396.1&Q6V7J5.
TMPJ-01069	Serpin A1e Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-...
TMPH-01054	CSNK1E Protein, Human, Recombinant (His)	Human	E. coli
	CSNK1E Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 51.3 kDa and the accession number is P49674.