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SCH28080

Catalog No. T16865 CAS 76081-98-6

SCH28080 inhibits gastric H+/K+-<a href="/target/ATPase" style="display: inline; color: #c13a36">ATPase</a> by K+-competitive binding (IC50: 20 nM in rabbit microsomal membranes).

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SCH28080, CAS 76081-98-6

Pack Size	Availability	Price/USD
5 mg	8-10 weeks	$ 970.00
50 mg	8-10 weeks	$ 1,980.00
100 mg	8-10 weeks	$ 2,500.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	SCH28080 inhibits gastric H+/K+-ATPase by K+-competitive binding (IC50: 20 nM in rabbit microsomal membranes).
Targets&IC50	H+/K+-ATPase, rabbit microsomal membranes:20 nM

Molecular Weight	277.32
Formula	C17H15N3O
CAS No.	76081-98-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Scott CK, et al. Studies on the mechanism of action of the gastric microsomal (H+ + K+)-ATPase inhibitors SCH 32651 and SCH 28080. Biochem Pharmacol. 1987 Jan 1;36(1):97-104. 2. Long JF, et al. Gastric antisecretory and cytoprotective activities of SCH 28080. J Pharmacol Exp Ther. 1983 Jul;226(1):114-20.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

SCH28080 76081-98-6 Membrane transporter/Ion channel ATPase SCH-28080 Inhibitor inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.