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SBE-β-CD

Name: SBE-β-CD
Brand: TargetMol
SKU: T16858
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T16858Cas No. 182410-00-0

Alias Sulfobutylether-β-Cyclodextrin

SBE-β-CD (Sulfobutylether-β-Cyclodextrin) is a β-cyclodextrin derivative with a sodium sulfonate salt separated from the lipophilic cavity by a butyl ether spacer group, or sulfobutylether. SBE-β-CD is widely used as a co-solvent in biological experiments.

SBE-β-CD

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Purity: 98%

Catalog No. T16858Alias Sulfobutylether-β-CyclodextrinCas No. 182410-00-0

Pack Size	Price	Availability
500 mg	$40	In Stock
1 g	$64	In Stock
5 g	$129	In Stock
10 g	$197	In Stock

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Purity:98%

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Product Introduction

Bioactivity

Description	SBE-β-CD (Sulfobutylether-β-Cyclodextrin) is a β-cyclodextrin derivative with a sodium sulfonate salt separated from the lipophilic cavity by a butyl ether spacer group, or sulfobutylether. SBE-β-CD is widely used as a co-solvent in biological experiments.
In vivo	METHODS: To study in vivo activity, MR-L2 (300 nl; 2 × 10-4 M; 1:20, DMSO in 20% SBE-β-CD) was microinfused into rat NAcs. RESULTS: MR-L2 significantly reduced inactive pressor pressures, whereas control administration of SBE-β-CD had no effect. [1]
Synonyms	Sulfobutylether-β-Cyclodextrin

Chemical Properties

Cas No.	182410-00-0
Relative Density.	1.46. Temperature:24 °C.
Color	White
Appearance	Solid

Storage & Solubility Information

Storage	keep away from moisture,store under nitrogen \| Pure form: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility Information	H2O: 250 mg/mL, Sonication is recommended. DMSO: 5.63 mg/mL, Sonication and heating are recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Sulfobutylether-beta-CyclodextrinSulfobutylether-b-CyclodextrinSBE-β-CDSBEβCDSBE-beta-CDSBE-b-CDSBE β CDInhibitorinhibit