polyphenol — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
S00015	Tea polyphenol		Apoptosis , Others , Autophagy
	Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea. Polyphenols are powerful antioxidants, which can reduce the risk of developing c...		Apoptosis , Others , Autophagy
T3921	Punicalagin		SARS-CoV , HBV
	Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumula...		SARS-CoV , HBV
T2S2108	Coixol	6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA	Others , Antibacterial
	1. Coixol (MBOA) acts as a central muscle relaxant with an anti-convulsant effect. 2. Coixol interacts with the pituitary to stimulate reproduction in voles. 3. Coixol has the ability to interact with FSH to stimulate fo...		Others , Antibacterial
TN7104	(+)-Epicatechin	Dexepicatechin	Others
	(+)-Epicatechin (Dexepicatechin) is a natural product and an antioxidant agent.		Others
T2807	Caffeic Acid		Lipoxygenase , Endogenous Metabolite , TRP/TRPV Channel
	Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities.		Lipoxygenase , Endogenous Metabolite , TRP/TRPV Channel
T3018	Protocatechualdehyde	Protocatechuic aldehyde,3,4-Dihydroxybenzaldehyde,Rancinamycin IV,Catechaldehyde	Reactive Oxygen Species , Antibacterial
	Protocatechualdehyde (3,4-Dihydroxybenzaldehyde), a natural polyphenol compound derived from radix Salviae Miltiorrhizae roots, exhibits diverse biological activities and finds extensive medicinal applications as an anti...		Reactive Oxygen Species , Antibacterial
T2999	Gastrodin	Gastrodine	Others
	Gastrodin (Gastrodine), an anti-inflammatory polyphenol, is extracted from Chinese natural herbal Gastrodia elata Blume. and benefits neurodegenerative diseases.		Others
T7792	Hispidin		Endogenous Metabolite , PKC
	Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties		Endogenous Metabolite , PKC
T19408	M-Coumaric acid		Endogenous Metabolite
	m-Coumaric acid, a polyphenol metabolite derived from caffeic acid, is produced by gut microflora. Its presence in human biofluids varies with diet.		Endogenous Metabolite
T6427	Butein	2’,3,4,4’-tetrahydroxy Chalcone	Apoptosis , EGFR , Others , PDE , Autophagy
	Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.		Apoptosis , EGFR , Others , PDE , Autophagy
T67709	Hispolon		Others
	Hispolon is a polyphenol. Hispolon can be isolated from Phellinus linteus. Hispolon exhibits anticancer, antidiabetic, antiviral, hepatoprotective, antioxidant, and anti-inflammatory activities.		Others
T0122	Bergenin	Cuscutin,Bengenin	Apoptosis , IL Receptor , Virus Protease , TNF , NF-κB , Antibacterial , NOD , Autophagy , Antifungal
	Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
T3807	(-)-Gallocatechin gallate	(-)-gallocatechin-3-O-gallate,(-)-Gallocatechol gallate,Gallocatechin gallate	Others
	(-)-Gallocatechin gallate ((-)-gallocatechin-3-O-gallate) is the polyphenol isolated from tea, with cancer-preventive activities. (-)-Gallocatechin gallate decreases osteoclastogenesis at 20 microM.		Others
T6917	Oleuropein		Apoptosis , Aromatase , ROS , PPAR
	Oleuropein is an antioxidant polyphenol isolated from olive leaf.		Apoptosis , Aromatase , ROS , PPAR
T4S0999	(2S)-Isoxanthohumol	Isoxanthohumol	Virus Protease , HSV
	1. (2S)-Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). 2. Isoxanthohumol is a polyphenol with antioxidant, anti-inflammatory, and antiangiogenic ...		Virus Protease , HSV
T13808	P-Coumaric Acid Ethyl Ester	Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate	Others , Drug Metabolite
	p-Coumaric Acid Ethyl Ester (Ethyl (E)-p-hydroxycinnamate) is the ethyl ester of p-Coumaric acid. p-Coumaric Acid is a common dietary polyphenol and also a potent immunosuppressive agent in treating autoimmune inflammato...		Others , Drug Metabolite
T5429	Theaflavin 3,3'-digallate	8-Gingerol,TFDG	Virus Protease , Antioxidant , HIV Protease , HSV
	Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...		Virus Protease , Antioxidant , HIV Protease , HSV
T2988	(-)-Epigallocatechin Gallate	Epigallocatechol Gallate,EGCG	Ferroptosis , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite , Autophagy
	(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor...
TN1722	Hamamelitannin		Antifection
	Hamamelitannin has cytotoxic, and antibiofilm activities. It increases the susceptibility of S. aureus to antibiotic treatment in in vivo Caenorhabditis elegans and mouse mammary gland infection models. It also has a hig...		Antifection
TN1969	N-(p-Coumaroyl) serotonin		PDGFR
	N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower. N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemia and antitumor activity, it may be beneficial in improving...		PDGFR