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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8740 | COH-SR4 | COH-SR4 (Mitochondria uncoupler SR4) | Others , AMPK |
COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation. COH-SR4 modulates amp-dependent kinase (ampk)-mammalian target of rapamycin (mtor) signaling, and inhibiting proli... | |||
T72291 | Mitochondria degrader-1 | ||
Mitochondria Degrader-1 (example 5) is a potent agent for inducing the autophagic degradation of damaged mitochondria. It is applicable in the research of various conditions including neurodegenerative, cancer, inflammat... | |||
T81631 | NV-354 | Mitochondria modulator-1 | |
Mitochondria Modulator-1, a mitochondrial regulator, enhances ATP production in mitochondria. It exhibits good oral bioavailability and blood-brain barrier permeability, along with robust plasma stability, showing promis... | |||
T9423 | Alkyne tyramide | Others | |
Alkyne tyramide is a clickable ascorbate peroxidase 2 (APEX2) probe which enable biotin-independent detection of labeled proteins. | |||
T7922 | Kresoxim-Methyl | Others , Mitochondrial Metabolism , Antifungal | |
Kresoxim-methyl is a strobilurin fungicide,inhibits conidial germination of V. inaequalis isolates from apple orchards . | |||
T40130 | Nur77 modulator 1 | Nur77 modulator 1 | Others |
Nur77 modulator 1 is a good Nur77 binder (KD = 3.58 μM). Nur77 modulator 1 up-regulates Nur77 expression, mediates sub-cellular localization of Nur77, induces Nur77-dependent ER stress and autophagy, and results in cell ... | |||
T3268 | Mildronate | Kvaterin,Meldonium,Quaterin | Hydroxylase |
Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption. | |||
T0846 | L-Carnitine | L(-)-Carnitine,Levocarnitine | Endogenous Metabolite , Fatty Acid Synthase |
L-Carnitine (L(-)-Carnitine) is an amino acid derivative. L-Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering substrate for oxidation and subsequent energy production. Fatty acids are utiliz... | |||
T5827 | BI-6C9 | Apoptosis , Others , Mitochondrial Metabolism | |
BI-6C9 is an inhibitor of tBid (Kd = 20 µM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death. | |||
T9211 | Mito-LND | Mito-Loidamine | OXPHOS , Reactive Oxygen Species , Mitochondrial Metabolism , Autophagy |
Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation. | |||
TN7108 | Urolithin C | Apoptosis , Calcium Channel , Reactive Oxygen Species , IGF-1R , Endogenous Metabolite | |
Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway. | |||
T10148 | 4-Hydroxynonenal | 4-HNE | Dehydrogenase , Endogenous Metabolite |
4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). | |||
T1885 | Siramesine hydrochloride | Lu 28-179 hydrochloride | Ferroptosis , Sigma receptor , lysosomal autophagy |
Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit a potent anticancer activity in vivo. | |||
TL0006 | Cichoric Acid | Dicaffeoyltartaric acid,Chicoric Acid | Reactive Oxygen Species , HIV Protease |
Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and ... | |||
T2203 | D-Carnitine hydrochloride | (S)-Carnitine Hydrochloride,L-Carnitine hydrochloride | Others , Endogenous Metabolite |
D-Carnitine hydrochloride ((S)-Carnitine Hydrochloride) is a constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemi... | |||
T6451 | Clodronic acid disodium salt | Loron,Clodronate Disodium,Lodronate | Others |
Clodronic acid disodium salt (Lodronate), a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption. | |||
T0866 | Propafenone | Rythmol,Propafenonum | Potassium Channel , MRP , Sodium Channel |
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.... | |||
T3604 | Sodium dichloroacetate | Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA) | Apoptosis , Dehydrogenase , Reactive Oxygen Species , PDK |
Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion chann... | |||
T6583 | MG-101 | ALLN,Ac-LLnL-CHO,Calpain inhibitor I,Calpain inhibitor-1,MG101 | Cysteine Protease , Proteasome |
MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins. | |||
T1205 | Chloramphenicol | Chlornitromycin,Levomycetin,Chloromycetin | ribosome , HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic |
Chloramphenicol (Chloromycetin), a broad-spectrum antibiotic, blocks bacterial protein synthesis. |