Search Result

Search Results for " lep "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1305	LEP(116-130)(mouse)		Others
	Leptin (116-130),mouse(C64H109N19O24S),a peptide with the sequence Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2. Leptin is an adipocyte-derived hormone that acts as a major regulator for food intake an...		Others
TP1305L	LEP(116-130)(mouse)TFA(258276-95-8 free base)		Complement System
	LEP(116-130)(mouse) is a synthetic leptin peptide fragment.		Complement System
T15735	Leptomycin B	CI 940,LMB	CRM1 , Antibiotic , Antifungal
	Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a ...		CRM1 , Antibiotic , Antifungal
T32088	Sovleplenib	HMPL 523,HMPL523,HMPL-523	Syk
	Sovleplenib (HMPL523) is an orally available, selective and potent inhibitor of the splenic tyrosine kinase SYK with an IC50 of 25 nM.Sovleplenib has antitumor activity and may be used in studies of immune thrombocytopen...		Syk
T29856	Aleplasinin	PAZ 417,PAZ417,PAZ-417	PAI-1
	Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies...		PAI-1
T34383	Rofleponide		Glucocorticoid Receptor
	Rofleponide is a synthetic glucocorticosteroid with a high affinity for the rat thymus glucocorticoid receptor.		Glucocorticoid Receptor
T37089	Iclepertin	BI-425809	GlyT
	Iclepertin (BI-425809) is an orally active and selective inhibitor of glycine transporter protein 1 (GlyT1).Iclepertin is used for the treatment of central nervous system disorders such as Alzheimer;s disease. Iclepertin...		GlyT
T126471	3'-Deoxy-4-O-methylepisappanol
	3'-Deoxy-4-O-methylepisappanol is a useful organic compound for research related to life sciences and the catalog number is T126471.
T125044	Lepidoside
	Lepidoside is a useful organic compound for research related to life sciences. The catalog number is T125044 and the CAS number is 32311-68-5.
T32643	Lepidimoide
	Lepidimoide is an allelopathic substance extracted from germinated cress (Lepirium sativum) seeds.
T25667	Leptocarpin acetate	Aceteylleptocarpin
	Leptocarpin acetate is used as a [35S]-methionine uptake inhibitor.
T73654	Selepressin acetate
	Selepressin acetate is a useful organic compound for research related to life sciences and the catalog number is T73654.
T76057	Glepaglutide acetate
	Glepaglutide (ZP1848) acetate is a long-acting glucagon-like peptide-2 (GLP-2) analogue and a potent GLP-2 receptor (GLP-2R) agonist. It significantly reduces fecal output and enhances intestinal absorption while also mi...
T35576	Phenylephrine-3-O-Sulfate
	Phenylephrine-3-O-sulfate is metabolite of the α1A-adrenergic receptor agonist phenylephrine formed via sulfation.
T32652	Leptosin I	( )-Leptosin I
	Leptosin I is an epitetrathiodioxopiperazine.
T33352	Methylepoxyproscillaridin
	Methylepoxyproscillaridin is a semisynthetic cardiac glycoside.
T32645	Leptine I, from Solanum chacoense	Leptine I
	Leptine I, from Solanum chacoense is a glycoalkaloid in the foliage of the wild potato species Solanum chacoense.
T32646	Leptocarpin
	Leptocarpin is a sesquiterpene lactone extracted from Leptocarpha rivularis.
T0453L	DL-Phenylephrine HCl	Eyelo,DL-Phenylephrine hydrochloride
	DL-Phenylephrine HCl is a selective agonist of the alpha1-adrenergic receptor.
T32642	Lepetine
	Lepetine is an alkaloid extracted from the root of Aconitum psedohuiliense.
T81940	Lepunafusp alfa	JR-171
	Lepunafusp alfa (JR-171) is a blood-brain barrier-penetrating fusion protein comprising J-Brain Cargo and α-L-iduronidase (IDUA), a lysosomal enzyme. This compound effectively lowers the levels of heparan sulfate (HS) an...
T126268	Chalepin
	Chalepin is a useful organic compound for research related to life sciences. The catalog number is T126268 and the CAS number is 118389-19-8.
T32211	Isoleptospermone
	Isoleptospermone is a bioactive chemical.
T32653	Leptosin J
	Leptosin J is a cytotoxic substance from a Leptosphaeria sp.
T69214	Ilepatril
	Ilepatril, also known as AVE-7688, is a vasopeptidase inhibitor for the treatment of hypertension.
T70119	Vernolepin
	Vernolepin is a natural reversible plant growth inhibitor.
T79638	Lepadin E		Glutathione Peroxidase
	Lepadin E, a notably cytotoxic compound, effectively stimulates ferroptosis via the canonical p53-SLC7A11-GPX4 pathway. By elevating p53 and repressing SLC7A11 and GPX4 expression, it heightens ROS and lipid peroxidation...		Glutathione Peroxidase
T79639	Lepadin H		Ferroptosis
	Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing lipid peroxidation. It simultaneously decreases SLC7A11 and GP...		Ferroptosis
T73751	Lepirudin
	Lepirudin, a recombinant form of hirudin, serves as a potent, irreversible inhibitor of thrombin, showcasing its anticoagulant efficacy in heparin-induced thrombocytopenia (HIT) [1].
T76221	Leptin (116-130)
	Leptin (116-130), a bioactive fragment of leptin, enhances synaptic plasticity in the hippocampus by promoting AMPA receptor trafficking to synapses. It preserves hippocampal synapse integrity and prevents neuronal cell ...
T76056	Glepaglutide
	Glepaglutide (ZP1848), a long-acting glucagon-like peptide-2 (GLP-2) analogue, functions as a potent agonist of the GLP-2 receptor (GLP-2R), effectively reducing fecal output and enhancing intestinal absorption, while al...
T77173	Eflepedocokin alfa
	Eflepedocokin alfa is a recombinant fusion protein that exhibits cell protective activity by comprising human IL-22 fused with the human IgG2-Fc domain. This compound activates the IL-22/IL-22R -mediated signal transduct...
T32648	Leptophos oxon	Leptophos OA,Leptophos oxygen analog,Phosvel oxon,Velsicol VCS O-analog
	Leptophos oxon is a phosvel analog-oxygen substituting sulfur.
T32654	Leptospermone
	Leptospermone is an essential oil from Leptospermum scoparium (manuka oil).
T32650	Leptoside
	Leptoside is a bioactive chemical.
T131468	O-4-Methoxybenzoylepilupinine hydrochloride
	O-4-Methoxybenzoylepilupinine hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T131468.
T78207	Lepzacitinib		JAK
	Lepzacitinib, a Janus kinase inhibitor, specifically targets JAK 1/3. It demonstrates an anti-inflammatory effect and efficacy in inhibiting atopic dermatitis as well as other skin diseases [1].		JAK
T126375	4-O-Methylepisappanol
	4-O-Methylepisappanol is a useful organic compound for research related to life sciences and the catalog number is T126375.
T25668	Leptolstatin
	Leptolstatin is used as a gap phase-specific inhibitor.
T35314	Zoleprodolol
	Zoleprodolol is a antagonist of adrenoreceptor.
T32641	Lepenine
	Lepenine is an alkaloid extracted from the root of Aconitum psedohuiliense.
T28745	Selepressin	FE 202158,FE202158
	Selepressin, an analog of vasopressin, is a potent, selective vasopressin V1a receptor agonist.
T63062	Lepidozin G
	Lepidozin G inhibits the growth of cancer cell lines (IC50=4.2±0.2 - 5.7±0.5 μM μM.) Lepidozin G induces PC-3 cell death using mitochondria-associated apoptosis.
T125310	Leptocarpinine
	Leptocarpinine is a useful organic compound for research related to life sciences and the catalog number is T125310.
T126035	Lepistamide A
	Lepistamide A is a useful organic compound for research related to life sciences. The catalog number is T126035 and the CAS number is 1334405-51-4.
T32640	Lepedine
	Lepedine is a diterpenoid alkaloid extracted from the root of Aconitum psedohuiliense.
T32651	Leptosin
	Leptosin is a novel glycoside.
T21132	Aglepristone
	Aglepristone is a synthetic steroidal antiprogestogen related to mifepristone and possesses some antiglucocorticoid activity. It is specifically used as an abortifacient in pregnant animals.
T68997	L-Phenylephrine
	L-Phenylephrine is an alpha-adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.
TP1356	Leptin (22-56), human
	Leptin(22-56),human is a peptide fragment of Leptin, which ACTS through a variety of subtypes of Ob-Rs.

Compounds

LEP(116-130)(mouse)

TP1305

Synonym:

Target: Others

LEP(116-130)(mouse)TFA(258276-95-8 free base)

TP1305L

Synonym:

Target: Complement System

Leptomycin B

T15735

Synonym: CI 940,LMB

Target: CRM1, Antibiotic, Antifungal

Sovleplenib

T32088

Synonym: HMPL 523,HMPL523,HMPL-523

Target: Syk

Aleplasinin

T29856

Synonym: PAZ 417,PAZ417,PAZ-417

Target: Glucocorticoid Receptor

3'-Deoxy-4-O-methylepisappanol

Leptocarpin acetate

T25667

Synonym: Aceteylleptocarpin

Phenylephrine-3-O-Sulfate

Synonym: ( )-Leptosin I

Target:

Methylepoxyproscillaridin

T33352

Synonym:

Target:

Leptine I, from Solanum chacoense

Synonym: Eyelo,DL-Phenylephrine hydrochloride

Target: Glutathione Peroxidase

Synonym: Leptophos OA,Leptophos oxygen analog,Phosvel oxon,Velsicol VCS O-analog

O-4-Methoxybenzoylepilupinine hydrochloride

4-O-Methylepisappanol

Synonym: FE 202158,FE202158

Leptin (22-56), human

TP1356

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T2937	4'-Demethylepipodophyllotoxin	4'-DMEP,4-Demethylepipodophyllotoxin,DMEP,4'-O-demethylepipodophyllotoxin	Microtubule Associated
	4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly.		Microtubule Associated
TN1858	Leptomerine		AChE
	Leptomerine (IC50 = 2.5 mM) shows potent anticholinesterasic activity.		AChE
T5297	3-Indolepropionic acid	Indolepropionic acid,IPA,indole-3-propionic acid	Antioxidant , Reactive Oxygen Species , Endogenous Metabolite
	3-Indolepropionic acid (Indolepropionic acid) is shown to be a powerful antioxidant with potential in the treatment for Alzheimer’s disease.
T25664	Lepidiline A	Macaline A	Others
	Lepidiline A (Macaline A) is a flavonoid lignin with anti-inflammatory activity. Lepidiline A showed cytotoxic activity against HL-60 cells with IC50 of 32.3 μM. It is the active ingredient of Lepidium meyenii Walpers, a...		Others
T38815	Millepachine		Apoptosis
	Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.		Apoptosis
T4S1999	Valepotriate	Valtrate	Apoptosis , HIV Protease
	Valepotriate (Valtrate) fraction can have sedative effects and affect behavioral parameters related to recognition memory. Valepotriates, a new class of cytotoxic and antitumor agents, they are very potent cytotoxic agen...		Apoptosis , HIV Protease
T0453	Phenylephrine hydrochloride	NCI-c55641,Phenylephrine HCl,(R)-(-)-Phenylephrine hydrochloride	Endogenous Metabolite , Adrenergic Receptor
	Phenylephrine hydrochloride (NCI-c55641) is a selective agonist of the α1-adrenergic receptor.		Endogenous Metabolite , Adrenergic Receptor
T17310	Phenylephrine	L-Phenylephrine,(R)-(-)-Phenylephrine	Adrenergic Receptor
	Phenylephrine ((R)-(-)-Phenylephrine) is a selective α1-adrenoceptor agonist ( pKi: 5.86, 4.87 and 4.70 for α1D, α1B, and α1A receptors respectively).		Adrenergic Receptor
TN1141	Isodeoxyelephantopin		NF-κB , Reactive Oxygen Species , Autophagy
	Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibit...		NF-κB , Reactive Oxygen Species , Autophagy
TN1079	Deoxyelephantopin		NF-κB
	Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling		NF-κB
T67922	Lepidiline C		Others
	Lepidiline C is a novel imidazoles alkaloids extracted from the root of Lepidium meenii Walpers of the brassaceae family. It has shown cytotoxic activity against HL-60 cells (IC50:27.7 μM).		Others
TN5644	Leptabiside A
	Leptabiside A is a natural product for research related to life sciences. The catalog number is TN5644 and the CAS number is 1900703-79-8.
TN3627	Chalepensin		ATPase , NADPH-oxidase , P450 , Antifection
	Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential drug interaction through mechanism-based inhibition. Chalepe...		ATPase , NADPH-oxidase , P450 , Antifection
TN6131	Leptostachyol acetate
	Leptostachyol acetate is a natural product for research related to life sciences. The catalog number is TN6131 and the CAS number is 35770-58-2.
T82480	Elephanoside D
	Elephanoside D (compound 8), a steroidal saponin, has been isolated from the stems of Yucca elephantipes Regel.
T11837	Leptomycin A		CRM1
	Leptomycin A, a metabolite derived from Streptomyces, acts as an inhibitor of CRM1 (exportin 1) and effectively suppresses HIV-1 replication. Compared to Leptomycin B, it exhibits lesser potency. Leptomycin A hampers the...		CRM1
TN5475	Trilepisflavan
	Trilepisflavan shows significant antimicrobial activity.
TN6180	6-Demethoxyleptostachyol acetate
	6-Demethoxyleptostachyol acetate is a natural product for research related to life sciences. The catalog number is TN6180 and the CAS number is 126298-48-4.
T82859	Blepharotriol
	Blepharotriol, a phenolic triterpene isolated from Maytenus blepharodes, exhibits antimicrobial activity, with a minimum inhibitory concentration (MIC) of 8-4 µg/ml against Bacillus subtilis. It also demonstrates cytotox...
T25665	Lepidiline B	Macaline B
	Lepidiline B is a flavonolignan that exhibits anti-inflammation activities. It is isolated from the roots of Lepidium meyenii Walpers (Brassicaceae).
T75472	Leptosin D
	Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50) value of 28.4 μM [1].
T75488	Leptosphaerodione
	Leptosphaerodione, a compound derived from the Remotididymella sp. fungus, functions as a potent inhibitor of the ubiquitin-proteasome system (UPS) and demonstrates cytotoxic effects in HeLa cells with an IC50 value of 3...
T75568	Z-Antiepilepsirine
	Z-Antiepilepsirine, an amide alkaloid present in Piper capense L.f., exhibits antiplasmodial properties, demonstrating an IC50 value of 27 µM against the W2 strain of Plasmodium falciparum [1].
TN5659	7-O-Methylepimedonin G
	7-O-Methylepimedonin G is a natural product for research related to life sciences. The catalog number is TN5659 and the CAS number is 2220243-40-1.
TN3374	Alepterolic acid		Others
	Alepterolic acid exhibits larvicidal properties against Aedes aegypti (L.) (Diptera, Culicidae), with LC50 of 87.3 ppm.		Others
TN4136	Glepidotin B		Others
	Glepidotin B is a natural product of Glycyrrhiza, Fabaceae. The catalog number is TN4136 and the CAS number is 87440-56-0. Glepidotin B can be used as a reference standard.		Others
TN6167	2-Demethoxyleptostachyol acetate
	2-Demethoxyleptostachyol acetate is a natural product for research related to life sciences. The catalog number is TN6167 and the CAS number is 139405-55-3.
TN5642	Leptabiside C
	Leptabiside C is a natural product for research related to life sciences. The catalog number is TN5642 and the CAS number is 1900703-81-2.
TN1357	Acetylepipodophyllotoxin		Others
	Acetylepipodophyllotoxin has insecticidal activity.		Others
TN3459	Ascleposide E		Others
	Ascleposide E is a natural product of Aucklandia, Asteraceae. The catalog number is TN3459 and the CAS number is 325686-49-5. Ascleposide E can be used as a reference standard.		Others
T32649	Leptophylloside	Isorutarin
	Leptophylloside is a kind of psoralen.

Natural Products

4'-Demethylepipodophyllotoxin

T2937

Synonym: 4'-DMEP,4-Demethylepipodophyllotoxin,DMEP,4'-O-demethylepipodophyllotoxin

Target: Microtubule Associated

3-Indolepropionic acid

T5297

Synonym: Indolepropionic acid,IPA,indole-3-propionic acid

Target: Antioxidant, Reactive Oxygen Species, Endogenous Metabolite

Target: Apoptosis, HIV Protease

Phenylephrine hydrochloride

T0453

Synonym: NCI-c55641,Phenylephrine HCl,(R)-(-)-Phenylephrine hydrochloride

Target: Endogenous Metabolite, Adrenergic Receptor

Phenylephrine

T17310

Synonym: L-Phenylephrine,(R)-(-)-Phenylephrine

Target: Adrenergic Receptor

Isodeoxyelephantopin

TN1141

Synonym:

Target: NF-κB, Reactive Oxygen Species, Autophagy

Target: ATPase, NADPH-oxidase, P450, Antifection

Leptostachyol acetate

6-Demethoxyleptostachyol acetate

7-O-Methylepimedonin G

2-Demethoxyleptostachyol acetate

Acetylepipodophyllotoxin

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01725	Leptin Receptor Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Leptin Receptor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is P48357-1.
TMPK-00050	Leptin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Leptin has key roles in the regulation of energy balance, body weight, metabolism, and endocrine function. Leptin levels are undetectable or very low in patients with lipodystrophy, hypothalamic amenorrhea, and congenita...
TMPJ-00606	Leptin Protein, Carassius auratus, Recombinant (His)	Carassius auratus	P. pastoris (Yeast)
	Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. In mammals, leptin ...
TMPJ-00052	Leptin Protein, Mouse, Recombinant	Mouse	E. coli
	Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have ...
TMPY-00874	Leptin Receptor Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	Leptin Receptor Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 121.4 kDa and the accession number is P48357-1.
TMPJ-00411	LEPR Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	LEPR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 150-180 KDa and the accession number is P48357.
TMPJ-00976	LEPR Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	LEPR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-10His tag. The predicted molecular weight is 120-150 KDa and the accession number is P48356.
TMPJ-00977	LEPR Protein, Mouse, Recombinant (mFc)	Mouse	HEK293 Cells
	LEPR Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 130-190 KDa and the accession number is P48356.
TMPJ-00975	LEPR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	LEPR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 130-190 KDa and the accession number is P48356.
TMPY-00875	Leptin Protein, Human, Recombinant	Human	E. coli
	Leptin Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is A4D0Y8.
TMPY-06375	Leptin Protein, Mouse, Recombinant (mFc)	Mouse	HEK293 Cells
	Leptin Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.33 kDa and the accession number is P41160.
TMPH-00017	AcpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc)	Acholeplasma laidlawii	E. coli
	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc...
TMPH-03075	3FTx-Oxy6 Protein, Oxyuranus microlepidotus, Recombinant (His & Myc & SUMO)	Oxyuranus microlepidotus	E. coli
	3FTx-Oxy6 Protein, Oxyuranus microlepidotus, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPK-01553	HLA-A*02:01&B2M&GP100 (YLEPGPVTA) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is in...
TMPK-01551	HLA-A*02:01&B2M&GP100 (YLEPGPVTA) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is in...
TMPK-01540	HLA-A*02:01&B2M&GP100 (YLEPGPVTA) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is in...