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Isodeoxyelephantopin

Catalog No. TN1141   CAS 38927-54-7

Isodeoxyelephantopin can inhibit the growth of various tumor cells.

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Isodeoxyelephantopin Chemical Structure
Isodeoxyelephantopin, CAS 38927-54-7
Pack Size Availability Price/USD Quantity
1 mg In stock $ 272.00
5 mg In stock $ 677.00
10 mg In stock $ 957.00
25 mg In stock $ 1,420.00
50 mg In stock $ 1,890.00
1 mL * 10 mM (in DMSO) In stock $ 673.00
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Purity: 99.88%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Isodeoxyelephantopin can inhibit the growth of various tumor cells.
In vitro Isodeoxyelephantopin inhibits the growth of A549 and T47D cells in a dose-dependent and time-dependent manner with IC50 values of 10.46 and 1.3 μg/mL, respectively. Heterodeoxyelephantin showed no significant toxicity to normal lymphocytes. Heterodeoxyelephinin-induced cell death is associated with activated caspase-3 expression, followed by cell cycle stagnation in G2/M phase [1]
Source
Molecular Weight 344.36
Formula C19H20O6
CAS No. 38927-54-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (159.72 mM)

TargetMolReferences and Literature

1. Isodeoxyelephantopin from Elephantopus scaber (Didancao) induces cell cycle arrest and caspase-3-mediated apoptosis in breast carcinoma T47D cells and lung carcinoma A549 cells.Chin Med. 2014 Apr 17;9:14.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Pancreatic Cancer Compound Library Anti-Fibrosis Compound Library Natural Product Library for HTS NO PAINS Compound Library Oxidation-Reduction Compound Library Antiparasitic Natural Product Library Autophagy Compound Library Pyroptosis Compound Library RO5 Drug-like Natural Product Library Anti-Breast Cancer Compound Library

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Keywords

Isodeoxyelephantopin 38927-54-7 Autophagy Immunology/Inflammation Metabolism NF-Κb Reactive Oxygen Species NF-κB inhibit Inhibitor Nuclear factor-κB Nuclear factor-kappaB inhibitor

 

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