Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Leptomerine is an alkaloid from stems of Esenbeckia leiocarpa Engl. (Rutaceae). Leptomerine shows as anticholinesterasic activity and can be used in Alzheimer Disease studies.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 137.00 | |
5 mg | In stock | $ 277.00 | |
10 mg | In stock | $ 467.00 | |
25 mg | In stock | $ 767.00 | |
50 mg | In stock | $ 1,070.00 | |
100 mg | In stock | $ 1,450.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 257.00 |
Description | Leptomerine is an alkaloid from stems of Esenbeckia leiocarpa Engl. (Rutaceae). Leptomerine shows as anticholinesterasic activity and can be used in Alzheimer Disease studies. |
Targets&IC50 | AChE:2.5 mM |
In vitro | Bioactivity-guided fractionation of the ethanol stems extract afforded the isolation of six alkaloids: leiokinine A, Leptomerine, kokusaginine, skimmianine, maculine and flindersiamine. All isolated compounds were tested for acetyl cholinesterase inhibition, in vitro and displayed anticholinesterasic activity. The alkaloid Leptomerine showed the highest activity (IC50 = 2.5 mM), similar to that of the reference compound galanthamine (IC50 = 1.7 mM). |
Source |
Molecular Weight | 201.26 |
Formula | C13H15NO |
CAS No. | 22048-97-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9 mg/mL (44.72 mM)
You can also refer to dose conversion for different animals. More
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Leptomerine 22048-97-1 Neuroscience AChE Cholinesterase (ChE) acetyl inhibit Inhibitor cholinesterase Anticholinesterasic Alzheimer activity inhibitor