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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP2157 | TAT-DEF-Elk-1 | TDE | Others |
TAT-DEF-Elk-1 is a cell-penetrating peptide Elk-1 inhibitor. | |||
TP2157L | TAT-DEF-Elk-1 TFA (1220751-16-5 free base) | TDE TFA,TAT-DEF-Elk-1 TFA | Others |
TAT-DEF-Elk-1 TFA is a cell-penetrating peptide Elk-1 inhibitor, mimics and specifically interferes with the DEF domain of Elk-1. TAT-DEF-Elk-1 blocks Elk-1 phosphorylation and prevents Elk-1 nuclear translocation withou... | |||
T81038 | TAT-DEF-Elk-1 TFA | TDE TFA | |
TAT-DEF-Elk-1 TFA (TDE TFA) is a cell-penetrating peptide that inhibits Elk-1 by mimicking its DEF domain and disrupting its function. It effectively blocks Elk-1 phosphorylation and its subsequent nuclear translocation,... | |||
T7447 | Adefovir | HBV , Reverse Transcriptase , Telomerase | |
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection. | |||
T19526 | Pradefovir mesylate | Pradefovir mesilate,Remofovir mesylate,Hepavir B | P450 |
Pradefovir mesylate (Hepavir B) is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with Km of 60 μM. | |||
T1565 | Deferiprone | Deferidone,CP20 | Others , HCV Protease , Ferroptosis , UGT |
Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity. | |||
T6552 | Istradefylline | KW-6002 | Adenosine Receptor |
Istradefylline (KW-6002)(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails. It has been used in trials studying the treatment and basic science of Drug Ab... | |||
T28449 | Pradefovir | ICN-2001-3,MB-6866,ICN-20013,MB-06866,Remofovir | HBV |
Pradefovir (Remofovir) is a reverse transcriptase inhibitor potentially for treatment of chronic HBV infection. Pradefovir is also a liver-targeted prodrug of adefovir. After metabolic activation, Pradefovir was converte... | |||
T124358 | Deferoxamine | Deferoxamine B,Desferrioxamine B | Apoptosis , Antioxidant , HIF , Autophagy |
Deferoxamine(Desferrioxamine B) is an iron chelator (binds Fe(III) and many other metal cations) that inhibits neuronopathy, may be used to modify the reduction of iron accumulation and deposition in tissues, and may imp... | |||
T24661 | Pridefine | Pridefina | |
Pridefine is an antidepressant drug. It acts as a balanced reuptake inhibitor of serotonin, dopamine, and norepinephrine. It also has some weak releasing activity. | |||
T1457 | Deferasirox | ICL 670,CGP-72670 | Others , Ferroptosis , Antibacterial |
Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload. | |||
T1996 | Defactinib | PF-04554878,VS-6063 | FAK |
Defactinib (VS-6063) is an orally bioavailable, small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. | |||
T13639 | Deferasirox (Fe3+ chelate) | Apoptosis | |
Deferasirox (Fe3+ chelate) is an orally available iron chelator with potential anticancer activity, inhibits the anti-apoptotic activity of MCL-1, and can be used to study iron overload. | |||
T19692 | Deferitrin | GT 56252,GT 56 252,GT-56252,GT-56-252 | Others |
Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload. | |||
T1637 | Deferoxamine Mesylate | desferrioxamine B,Desferrioxamine B mesylate,DFO,DFOM | Mitophagy , Beta Amyloid , Others , Ferroptosis , HIF/HIF Prolyl-Hydroxylase , Autophagy |
Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1α levels and i... | |||
T29328 | 21-deacetyldeflazacort | Others | |
21-Desacetyl Deflazacort is a metabolite of Deflazacort (sc-204709), which is a systemic corticosteroid and a derivative of prednisolone. It is used for lupus and rheumatoid arthritis. | |||
T31362 | Deferitazole | SPD602,FBS 0701,SPD-602,FBS0701,FBS-0701,SPD 602 | Others |
Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator. | |||
T1675 | Adefovir dipivoxil | Hepsera,GS 0840,Preveon | Others , HBV , Reverse Transcriptase |
Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficienc... | |||
T15092 | Defactinib hydrochloride | VS-6063 hydrochloride,PF 04554878 hydrochloride | FAK |
Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK. Which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner. | |||
T76070 | Defensin HNP-1 human TFA | ||
Defensin HNP-1 Human TFA, a human neutrophil peptide (HNP), plays a role in the early development of atherosclerosis by contributing to endothelial cell dysfunction. Additionally, it has demonstrated broad-spectrum antim... | |||
T35426 | β-Defensin-1 (human) (trifluoroacetate salt) | ||
β-Defensin-1 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth ofB. adolescentis,L. acidophilus... | |||
T80045 | Defensin HNP-3 human | Antibiotic | |
Defensin HNP-3 human, a cytotoxic antibiotic peptide referred to as "defensin," exhibits inhibitory effects on Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. This compound is first synthesized as a ... | |||
T80362 | Human α-Defensin 6 | ||
Human α-Defensin 6, a 32-residue, cysteine-rich peptide, plays a crucial role in mucosal immunity by inhibiting bacterial invasion. It achieves this through the formation of ordered self-assembly fibrils and nanonets, wh... | |||
T76063 | Beta-defensin 1, pig | ||
Beta-defensin 1, pig, is an antimicrobial peptide predominantly located in the tongue mucosa of pigs. It exhibits activity against a variety of bacteria including Escherichia coli, Salmonella typhimurium, Listeria monocy... | |||
T80375 | Human α-defensin 5 | Parasite | |
Human α-defensin 5 is an antiviral peptide that inhibits the infection of non-enveloped viruses such as AdV, HPV, and polyomaviruses, with an IC50 range of 0.6-1.25 μM specifically for HPV16. It functions by binding to t... | |||
T76503 | Defensin NP-3A | ||
Defensin NP-3A (NP-3A; Corticostatin 1), a human granulocyte peptide, exhibits anti-ACTH activity. It belongs to the defensins, a group of antimicrobial peptides known for their antimicrobial and cytotoxic activities [1]... | |||
T35452 | β-Defensin-3 (human) (trifluoroacetate salt) | ||
β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and ... | |||
T31363 | Deferitazole magnesium | FBS0701,FBS-0701,SSP-004184,SHP-602,SHP602,Deferitazole free base | |
Deferitazole magnesium is a potential chelator for iron overload treatment. | |||
T76064 | Beta-defensin 103 isoform X1, pig | ||
Beta-defensin 103 isoform X1, pig, is an antimicrobial peptide prevalent in various organisms, playing a crucial role in the initial defense strategy of their innate immune system against pathogens [1]. | |||
T35453 | β-Defensin-4 (human) (trifluoroacetate salt) | ||
β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at... | |||
T40470 | Human β-defensin-2 | Human β-defensin-2,HβD-2 | |
Human β-defensin-2 (HβD-2) is a cationic skin-antimicrobial peptide (SAP) characterized by its small size and rich cysteine content. It is produced by various epithelial cells and exhibits potent antimicrobial properties... | |||
T41135 | Defensin HNP-1 human | ||
Defensin HNP-1 human is a Human neutrophil peptides (HNPs), involved in endothelial cell dysfunction at the time of early atherosclerotic development.Defensin HNP-1 human can regulate the growth of atherosclerosis. | |||
T80323 | Bovine neutrophil beta-defensin 12 | BNBD-12 | |
Bovine neutrophil beta-defensin 12, an antimicrobial peptide originating from bovine neutrophils, exhibits antibacterial properties against Escherichia coli and Staphylococcus aureus [1]. | |||
T76064L | Beta-defensin 103 isoform X1, pig TFA | ||
Beta-defensin 103 isoform X1, pig TFA, is an antimicrobial peptide present in various living organisms, playing a crucial role in the initial defense of their innate immune system against pathogens [1]. | |||
T76501 | Defensin HNP 4 | ||
Defensin HNP 4 (HNP 4), an 11-amino acid segment derived from HNP-41-11, exhibits inhibitory effects against both multidrug-resistant and non-resistant strains [1]. | |||
T81502 | Pezadeftide | Antibiotic | |
Pezadeftide, a potent antifungal peptide, readily penetrates fungal cells, eliciting an immediate mitochondrial response that leads to hyperpolarization of the mitochondrial membrane [1]. | |||
T25219 | Cedefingol | SPC-101210,SP101210,SPC 101210 | |
Cedefingol is an antineoplastic agent. | |||
T81652 | Nordefrin | (±)-Cobefri | |
Nordefrin ((±)-Cobefri), a derivative of Norepinephrine, acts as a vasoconstrictor [1]. | |||
T35451 | β-Defensin-2 (human) (trifluoroacetate salt) | ||
β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cari... | |||
T34741 | Sulfidefluor-7 AM | SF7-AM | |
Sulfidefluor-7 AM (SF7-AM) is an effective and cell permeable fluorescent probe for hydrogen sulfide (h2s). Sulfidefluor-7 AM contains acetoxy-methyl ester, which is hydrolyzed intracellular to capture the probe. | |||
T76063L | Beta-defensin 1, pig TFA | ||
Beta-defensin 1, pig TFA, an antimicrobial peptide predominantly located in the tongue mucosa of pigs, exhibits activity against a diverse range of bacteria including Escherichia coli, Salmonella typhimurium, Listeria mo... | |||
T38103 | Defensin HNP-3 (human) (trifluoroacetate salt) | ||
Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg/mL. It also inhibits growth o... | |||
T41134 | Defensin HNP-2 human | ||
Defensin HNP-2 is a naturally occurring antibiotic and monocyte chemotactic peptide synthesized by human neutrophils. | |||
T40550 | Human β-defensin-1 | Human β-defensin-1,HβD-1 | |
Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by epithelial surfaces, circulatory cells, and cells of the reproductive tract. It exhibits antimicrobial activity against ... | |||
T39683 | Human β-defensin-3 | Human β-defensin-3,HβD-3 | |
Human β-defensin-3 (HβD-3) is an antibiotic antimicrobial peptide synthesized by epithelial cells. It exhibits potent antimicrobial properties and mitigates inflammatory cytokine responses. HβD-3 efficiently targets vari... | |||
T10139 | 4-Desmethyl Istradefylline | Others | |
4-Desmethyl Istradefylline is a Istradefylline metabolite. Istradefylline is a very potent, selective, and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease. | |||
T71036 | Adefovir monophosphate | ||
Adefovir monophosphate is an antiviral acyclic nucleoside phosphonate (ANP) analog with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficiency virus (HIV). It is an orally-administered acyclic... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T80344 | Aeschna defensin | ||
Aeschna defensin is an antimicrobial peptide sourced from the hemolymph of aquatic dragonfly larvae, exhibiting potent activity against Gram-positive bacteria [1]. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02590 | HMGB1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
HMGB1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.3 kDa and the accession number is P63158. | |||
TMPY-00542 | DEFB127 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
DEFB127 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 31.8 kDa and the accession number is A0A2J8MRU9. | |||
TMPY-00346 | DEFA3 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
DEFA3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.8 kDa and the accession number is P59666. | |||
TMPJ-01243 | DEFB4 Protein, Human, Recombinant | Human | E. coli |
Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1,... | |||
TMPH-03567 | Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO) | Staphylococcus aureus | E. coli |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has b... | |||
TMPY-02835 | DEFB103A Protein, Human, Recombinant (His) | Human | E. coli |
Beta-defensin 3 is a member of the defensin family. Defensin family is comprised by microbicidal and cytotoxic peptides made by neutrophils. Members of the beta-defensin 3 family are highly similar in protein sequence. B... | |||
TMPH-01006 | DEFB129 Protein, Human, Recombinant (His & Myc) | Human | P. pastoris (Yeast) |
Has antibacterial activity. DEFB129 Protein, Human, Recombinant (His & Myc) is expressed in yeast with C-6xHis-Myc tag. The predicted molecular weight is 21.8 kDa and the accession number is Q9H1M3. | |||
TMPY-00336 | Simian immunodeficiency virus (SIV) (isolate 216.94.A2) gp120 Protein (His) | SIV | HEK293 Cells |
Simian immunodeficiency virus (SIV) (isolate 216.94.A2) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is E2EXP2. | |||
TMPH-00061 | Defensin-1 Protein, Apis mellifera carnica, Recombinant (His & KSI) | Apis mellifera carnica | E. coli |
Found in royal jelly and in hemolymph, potent antibacterial protein against Gram-positive bacteria at low concentration. Defensin-1 Protein, Apis mellifera carnica, Recombinant (His & KSI) is expressed in E. coli express... | |||
TMPH-03148 | DEFB126 Protein, Pongo pygmaeus, Recombinant (GST) | Pongo pygmaeus | P. pastoris (Yeast) |
DEFB126 Protein, Pongo pygmaeus, Recombinant (GST) is expressed in yeast with N-GST tag. The predicted molecular weight is 31.9 kDa and the accession number is A4H244. | |||
TMPH-00063 | Defensin-1 Protein, Apis mellifera, Recombinant (His) | Apis mellifera | E. coli |
Found in royal jelly and in hemolymph, potent antibacterial protein against Gram-positive bacteria at low concentration. Defensin-1 Protein, Apis mellifera, Recombinant (His) is expressed in E. coli expression system wit... | |||
TMPH-00678 | Peptide deformylase Protein, E. coli O157:H7, Recombinant (His & SUMO) | E. coli | E. coli |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has b... | |||
TMPH-02544 | DEFB4 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CC... | |||
TMPH-02503 | DEFA1 Protein, Mouse, Recombinant (GST & His) | Mouse | E. coli |
Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium. DEFA1 Protein, Mouse, Recombinant (GST & His) is expressed in ... | |||
TMPY-01115 | DEFB119 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
DEFB119 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 33.9 kDa and the accession number is Q8N690-1. | |||
TMPH-02504 | DEFA5 Protein, Mouse, Recombinant (GST) | Mouse | E. coli |
Probably contributes to the antimicrobial barrier function of the small bowel mucosa. DEFA5 Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31... | |||
TMPH-01772 | DEFA1 Protein, Human, Recombinant (GST) | Human | E. coli |
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing thei... | |||
TMPH-00702 | Peptide deformylase Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has b... | |||
TMPH-03101 | DEFB1 Protein, Pig, Recombinant (GST) | Sus scrofa (Pig) | E. coli |
Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization i... | |||
TMPY-00331 | Simian immunodeficiency virus (SIV) (isolate SIVmac251v31523ru28) gp120 Protein (His) | SIV | HEK293 Cells |
Simian immunodeficiency virus (SIV) (isolate SIVmac251v31523ru28) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.6 kDa and the accession number is D7PU90. | |||
TMPJ-00003 | DEFB1 Protein, Human, Recombinant | Human | E. coli |
β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a si... | |||
TMPJ-00667 | DEFB4A Protein, Human, Recombinant | Human | E. coli |
β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of t... | |||
TMPH-02543 | DEFB33 Protein, Mouse, Recombinant (His & Myc & SUMO) | Mouse | E. coli |
Has antibacterial activity. | |||
TMPY-00328 | Simian immunodeficiency virus (SIV) (isolate F236) gp120 Protein (His) | SIV | HEK293 Cells |
Simian immunodeficiency virus (SIV) (isolate F236) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.8 kDa and the accession number is P12492. | |||
TMPH-02542 | DEFB19 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Has antibacterial activity. | |||
TMPH-03509 | Simian immunodeficiency virus (SIV) (isolate PBj14/BCL-3) Vpx Protein (His & SUMO) | SIV | E. coli |
Simian immunodeficiency virus (SIV) (isolate PBj14/BCL-3) Vpx Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 28.9 kDa and the accession number is P... | |||
TMPH-03566 | Peptide deformylase Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | P. pastoris (Yeast) |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has b... | |||
TMPH-00460 | Defensin-like protein 1 Protein, Dahlia merckii, Recombinant (B2M & His) | Dahlia merckii | E. coli |
Defensin-like protein 1 Protein, Dahlia merckii, Recombinant (B2M & His) is expressed in E. coli. | |||
TMPH-02541 | Beta Defensin 1/DEFB1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization i... | |||
TMPH-00679 | Peptide deformylase Protein, E. coli O157:H7, Recombinant (His) | E. coli | P. pastoris (Yeast) |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has b... | |||
TMPY-04170 | DEFB1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The DEFB1 gene, encoding for the constitutively expressed human beta-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been rep... | |||
TMPH-01005 | DEFB128 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Has antibacterial activity. DEFB128 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16.0 kDa and the accession number is Q7... | |||
TMPH-02545 | DEFB6 Protein, Mouse, Recombinant (His & KSI) | Mouse | E. coli |
Has potent antibacterial activity against E.coli (ATCC 25922). DEFB6 Protein, Mouse, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 19.8 kDa and ... | |||
TMPH-03082 | DEFB106A Protein, Pan troglodytes, Recombinant (His & KSI) | Chimpanzee | E. coli |
Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. DEFB106A Protein, Pan troglodytes, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molec... |