ca inhibitor 2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T79681	CA inhibitor 2		Carbonic Anhydrase
	Compound 4H is a potent carbonic anhydrase inhibitor with an IC50 value of 0.033 μM [1].		Carbonic Anhydrase
T10659	Ca2+ channel agonist 1		Calcium Channel , CDK
	Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction.		Calcium Channel , CDK
T4693	2-Aminoethyl diphenylborinate	2-Aminoethoxydiphenyl borate,2-APB	Calcium Channel , TRP/TRPV Channel
	2-Aminoethyl diphenylborinate (2-APB) is a chemical that acts to inhibit both IP3 receptors and TRP channels (although it activates TRPV1, TRPV2, & TRPV3 at higher concentrations).		Calcium Channel , TRP/TRPV Channel
T8944	TTA-A2		Calcium Channel
	TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels ...		Calcium Channel
TN7108	Urolithin C		Apoptosis , Calcium Channel , Reactive Oxygen Species , IGF-1R , Endogenous Metabolite
	Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
T40376	L-Phenylalanine-15N	(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N	Calcium Channel
	L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) is the 15N-labeled L-Phenylalanine. L-Phenylalanine is an essential amino acid isolated from Escherichia coli . L-Phenylalanine is a α2δ subunit of voltage-dep...		Calcium Channel
T3377	L-Phenylalanine	(S)-2-Amino-3-phenylpropionic acid,phenylalanine,3-Phenyl-L-alanine	Calcium Channel , Endogenous Metabolite , iGluR
	L-Phenylalanine (3-Phenyl-L-alanine) is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.		Calcium Channel , Endogenous Metabolite , iGluR
T1101	Minocycline hydrochloride	Minocycline HCl	HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor...		HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
T1606	Fasudil	HA-1077,AT877	ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy
	Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T3060	Fasudil hydrochloride	Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T21907	PACOCF3	1,1,1-trifluoroheptadecan-2-one,Palmityltrifluoromethylketone	Phospholipase
	PACOCF3 (Palmityltrifluoromethylketone) (Palmityltrifluoromet hylketone) is an inhibitor of Ca(2+)-independent phospholipase A2(PLA2) with an IC 50 of 3.8 μM. PACOCF3 alters Ca 2+ signaling in renal tubular cells [1] [2]...		Phospholipase
T77631	Enpp/Carbonic anhydrase-IN-2		Apoptosis , PDE , Carbonic Anhydrase
	Enpp/Carbonic anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.07, 0.74, 0.33, 0.68, respectively.Enpp/Carbonic anhydrase-I...		Apoptosis , PDE , Carbonic Anhydrase
T36758	CAIX Inhibitor S4	S4	Carbonic Anhydrase
	CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM.		Carbonic Anhydrase
T21294	Polmacoxib	CG-100649,CG100649,CG 100649	COX , Carbonic Anhydrase
	Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through...		COX , Carbonic Anhydrase
T16564	PPADS tetrasodium		P2X Receptor , Na+/Ca2+ Exchanger
	PPADS tetrasodiuma is a potent P2X receptor antagonist and inhibitor of the inverse mode of Na/Ca²⁺ exchange in guinea pig airway smooth muscle and is neuroprotective against glutamate/NMDA toxicity.PPADS tetrasodiuma in...		P2X Receptor , Na+/Ca2+ Exchanger
T21509	CA 074		Cysteine Protease
	CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates retinopathy and optic neuritis in experimental autoimmune encephalom...		Cysteine Protease
T24846	T16A(inh)-C01	T16A(inh) C01
	T16A(inh)-C01 is the Ca(2+)-activated Cl(-) Channel, Ano1 class C inhibitor.
T24847	T16A(inh)-D01	T16A(inh) D01,T16Ainh-D01,T16AinhD01,T16A(inh)D01,T16Ainh D01
	T16A(inh)-D01 is the Ca(2+)-activated Cl(-) Channel, Ano1 class D inhibitor.
T27639	ITH-12575
	ITH-12575 is an inhibitor of Mitochondrial Na+/Ca2+ exchange (mNCX). ITH12575 reduces Ca(2+) influx through CALHM1 at low micromolar concentrations.
T24845	T16A(inh)-B01	T16Ainh-B01,T16A(inh)B01,T16AinhB01,T16Ainh B01
	T16A(inh)-B01 is the Ca(2+)-activated Cl(-) Channel, Ano1 class B inhibitor.