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Minocycline hydrochloride

Catalog No. T1101   CAS 13614-98-7
Synonyms: Minocycline HCl

Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochloride can cause both an acute hepatitis-like syndrome occurring within 1 to 3 months of starting therapy or a more insidious chronic hepatitis with autoimmune features typically after long-term treatment.

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Minocycline hydrochloride Chemical Structure
Minocycline hydrochloride, CAS 13614-98-7
Pack Size Availability Price/USD Quantity
25 mg In stock $ 38.00
50 mg In stock $ 50.00
100 mg In stock $ 62.00
200 mg In stock $ 92.00
1 mL * 10 mM (in DMSO) In stock $ 50.00
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Purity: 100%
Purity: 100%
Purity: 99.89%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochloride can cause both an acute hepatitis-like syndrome occurring within 1 to 3 months of starting therapy or a more insidious chronic hepatitis with autoimmune features typically after long-term treatment.
Synonyms Minocycline HCl
Molecular Weight 493.94
Formula C23H28ClN3O7
CAS No. 13614-98-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 12.4 mg/mL (25 mM)

DMSO: 49.4 mg/mL (100 mM)

TargetMolReferences and Literature

1. Brogden RN, et al. Drugs, 1975, 9(4), 251-291. 2. Zhu S, et al. Nature, 2002, 417(6884), 74-78. 3. Wang X, et al. Proc Natl Acad Sci U S A, 2003, 100(18), 10483-10487.

TargetMolCitations

1. Wang W, Liu W Z, Wang Z L, et al. Spinal microglial activation promotes perioperative social defeat stress-induced prolonged postoperative pain in a sex-dependent manner. Brain, Behavior, and Immunity. 2021 2. Shui, Sufang, et al. Non-enzymatic lipid peroxidation initiated by photodynamic therapy drives a distinct ferroptosis-like cell death pathway. Redox Biology. (2021): 102056

Related compound libraries

This product is contained In the following compound libraries:
Approved Drug Library Stem Cell Differentiation Compound Library Orally Active Compound Library Drug-induced Liver Injury (DILI) Compound Library Hematopoietic Toxicity Compound Library Anti-COVID-19 Compound Library Antibiotics Library Bioactive Compounds Library Max Clinical Compound Library NO PAINS Compound Library

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Keywords

Minocycline hydrochloride 13614-98-7 Chromatin/Epigenetic Metabolism Microbiology/Virology HIF/HIF Prolyl-Hydroxylase Antibacterial Antibiotic Calcium Channel Inhibitor HIF-PH Myocardial ischemia MDM-2/p53 PI3K/Akt Apoptosis Potassium Channel Minocycline HCl inhibit Ca2+ channels Hypoxia-inducible factors HIFs infection L-type Ca2+ channel stroke cerebral ischemia Ca channels acinetobacter neuroprotective Minocycline Minocycline Hydrochloride KcsA ovarian cancer Mitochondrial ATP-sensitive potassium Ventricular arrhythmia Bacterial inhibitor

 

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