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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14195 | ALS-8112 | Others | |
ALS-8112 is a inhibitor of respiratory syncytial virus (RSV) polymerase. The 5'-triphosphate form of ALS-8112 inhibits RSV polymerase (IC50: 0.02 μM). | |||
T29909 | ALS-I | ALS1,Acid-Liable Surfactant-1,ALS 1,ALS-1 | |
ALS-1 is an acid-Liable surfactant. | |||
T14336 | Allitinib | AST-1306,ALS 1306 | EGFR |
Allitinib (AST-1306) (AST-1306) has anti-cancer activity,and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1] | |||
T26602 | ALS-I-41 | ||
ALS-I-41 is a novel, potent and selective antagonist of oxytocin receptor. | |||
TQ0034 | Lumicitabine | ALS-8176,ALS-008176 | RSV |
Lumicitabine (ALS-008176) is an inhibitor of RSV polymerase. | |||
T29970 | AMG-222 | AMG 222,ALS-2-0426 free base,ALS-2-0426,ALS-20426 | |
AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes. | |||
T19859 | Nicosulfuron | Milagro,Accent,Motivell | Others |
Nicosulfuron (Milagro) is a pesticide that works by inhibiting the acetolactate synthase enzyme. Nicosulfuron has not been found to induce mutagenic or carcinogenic effects. Nicosulfuron is a herbicide to protect corn cr... | |||
T39924 | NF-κΒ activator 2 | NF-κB | |
NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM. By enhancing NF-κB expression and activation, it induces SOD 2 synthesis, rendering it useful for amyo... | |||
T3198L | PRE-084 hydrochloride | Sigma receptor | |
PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay). | |||
T17216 | Valspodar | PSC 833 | P-gp |
Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a chemical sensitizer to study advanced epithelial ovarian cancer. | |||
T67848 | Valsartan Methyl Ester | RAAS | |
Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM. | |||
T4615 | Balsalazide sodium hydrate | Balsalazide disodium dihydrate,Balsalazide disodium salt dihydrate,Balsalazide disodium | STAT , Interleukin |
Balsalazide sodium hydrate (Balsalazide disodium) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide sodium hydrate is a new 5-aminosalicylic acid (5-ASA) containing prodrug.... | |||
T14358 | Avoralstat | BCX4161 | Others |
Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema. | |||
T6716 | Valsartan | Diovan,Tareg,CGP 48933 | RAAS |
Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension. | |||
T2318 | Sacubitril/Valsartan | Sacubitril mixture with Valsartan,Valsartan,Sacubitril,LCZ696 | Apoptosis , RAAS , Neprilysin |
Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure. | |||
T39350 | Sebetralstat | KVD900 | Others |
Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases. | |||
T7426 | ALSTERPAULLONE | Apoptosis , GSK-3 , CDK | |
Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec | |||
T0498 | Salsalate | Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171 | Reactive Oxygen Species , COX |
Salsalate (Sasapyrine) is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic activities. | |||
TQ0277 | Pralsetinib | Blu667 | c-RET |
Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion). | |||
T76917 | Balstilimab | ||
Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1 [1] . | |||
T13283 | Valsartan Ethyl Ester | Others | |
Valsartan Ethyl Ester is an impurity of Valsartan. Valsartan is an antagonist of the angiotensin II receptor and for the treatment of high blood pressure and heart failure. | |||
T31379 | DeOxy-DALSiR | deOxy DALSiR | |
deOxy-DALSiR is a selective and sensitive near-infrared fluorescent probe for visualization of endogenous nitric oxide in living cells and animals. | |||
T29911 | Alstonidine | ||
Alstonidine is a biochemical. | |||
T13071 | Talsaclidine | Others | |
Talsaclidine is an agonist of muscarinic with preferential neuron-stimulating properties. Talsaclidine is a full agonist at the M1 subtype, and as a partial agonist at the M2 and M3 subtypes. | |||
T35869 | Berotralstat | ||
Berotralstat (BCX7353) is a second-generation, synthetic, and orally active plasma kallikrein inhibitor with low toxicity. It is highly specific and effectively used in the research of hereditary angioedema (HAE) attacks... | |||
T68555 | Alsterpaullone, 2-Cyanoethyl | ||
Alsterpaullone, 2-Cyanoethyl is a selective dual inhibitor of Cdk1/cyclin B and GSK-3β. | |||
T123974 | Salsoloside C | ||
Salsoloside C is a useful organic compound for research related to life sciences. The catalog number is T123974 and the CAS number is 89827-13-4. | |||
T29910 | Alseroxylon | Egalin | |
Alseroxylon can be used to treat hypertension. | |||
T10823 | Trans-Pralsetinib | cis-Pralsetinib,cis-BLU-667 | c-RET |
trans-Pralsetinib (trans-BLU-667) is an inhibitor of rearranged during transfection (RET). | |||
T76297 | Alsactide | ||
Alsactide, an adrenocorticotropic hormone (ACTH) agonist and a heptadecapeptide analogue, is utilized in the study of the central nervous system [1]. | |||
T78287 | Alsevalimab | ||
Alsevalimab is a human monoclonal antibody targeting B7-H4 [1]. | |||
T131396 | Carnegine (Pectenine, N-Methylsalsolidine) | ||
Carnegine (Pectenine, N-Methylsalsolidine) is a useful organic compound for research related to life sciences and the catalog number is T131396. | |||
T23417 | Talsupram hydrochloride | Others | |
noradrenalin re-uptake inhibitor | |||
T131573 | Isosalsolidine | ||
Isosalsolidine is a useful organic compound for research related to life sciences and the catalog number is T131573. | |||
T131406 | Venalstonine | ||
Venalstonine is a useful organic compound for research related to life sciences and the catalog number is T131406. | |||
T29912 | Alstonidine acetate trihydrate | Alstonidine acetyl deriv trihydrate | |
Alstonidine acetate trihydrate is a biochemical. | |||
T63507 | Feniralstat | ||
Feniralstat is a pyrazole derivative, a potent inhibitor of kallikrein, which inhibits human plasma kinase (pKal) (IC50: 6.7 nM).Feniralstat does not inhibit human KLK1, human FXIa and human factor Xlla (IC50 >40 μM). | |||
T124585 | Rac Salsolinol, Hydrobromide | ||
rac Salsolinol, Hydrobromide is a useful organic compound for research related to life sciences. The catalog number is T124585 and the CAS number is 59709-57-8. | |||
T81560 | Palsucibep pegol | ||
Palsucibep pegol is an engineered protein that specifically binds to human lipocalin-2. It also targets hepcidin [1]. | |||
T68829 | (+/-)-Salsolinol Hydrochloride | ||
(+/-)-Salsolinol hydrochloride is a full Gi protein agonist of the μ-opioid receptor (μOR). | |||
T68890 | Desvaleryl Valsartan | ||
Desvaleryl valsartan is a potential impurity found in commercial preparations of the angiotensin II type 1 (AT1) receptor antagonist valsartan. It is a degradation product formed under acidic conditions. | |||
T4571 | Balsalazide | Balsalazido | Lipoxygenase , STAT , Interleukin |
Balsalazide (Balsalazido) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease. | |||
T29911L | Alstonidine acetate | O-Acetylalstonidine | |
Alstonidine acetate is a biochemical. | |||
TQ0277L | Pralsetinib HCl (2097132-94-8 free base) | Pralsetinib HCl,Pralsetinib hydrochloride,BLU-667,BLU667,BLU 667 | |
Pralsetinib is a selective and next-generation RET inhibitor (IC50: 0.3-0.4 nM for WT RET, RET mutants V804L, V804M, M918T, and CCDC6-RET fusion). BLU-667 is an effective and selective inhibitor of RET mutations, fusions... | |||
T70161 | Berotralstat HCl | ||
Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated wi... | |||
T35725 | 4-hydroxy Valsartan | ||
4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan . It reduces platelet aggregation induced by epinephrine and collagen but not ADP in human whole blood. | |||
T20564 | Valsartan benzyl ester | Valsartan impurity B,Valsartan related compound C | |
Valsartan benzyl ester is a intermediate of Valsartan. | |||
T13282 | Valsartan-d9 | CGP-48933 D9 | Others |
Valsartan D9 is a deuterium-labeled valsartan. Valsartan is an antagonist of the angiotensin II receptor and for the treatment of high blood pressure and heart failure. | |||
T13553 | Arimoclomol | BRX-220 free base | HSP |
Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS). | |||
T60120 | SOD1-Derlin-1 inhibitor 56-59 | Others | |
SOD1-Derlin-1 inhibitor 56-59 is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor 56-59 is potential in Amyotrophic lateral sclerosis (ALS) research. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2830 | Betulinic acid | ALS-357,Lupatic acid,Betulic acid | Apoptosis , Mitophagy , NF-κB , HIV Protease , Topoisomerase , Endogenous Metabolite , Aminopeptidase , Autophagy |
Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory propert... | |||
T22911 | β-N-methylamino-L-alanine hydrochloride | L-BMAA hydrochloride | Others |
β-N-methylamino-L-alanine hydrochloride (L-BMAA hydrochloride) is a neurotoxin produced by cyanobacteria. L-BMAA hydrochloride could cause amyotrophic lateral sclerosis (ALS) and possibly other neurodegenerative diseases... | |||
TN3398 | Alstolenine | Others | |
Alstolenine is a natural product of Alstonia, Apocynaceae. The catalog number is TN3398 and the CAS number is 85769-33-1. Alstolenine can be used as a reference standard. | |||
TN2267 | Tetrahydroalstonine | Adrenergic Receptor | |
Tetrahydroalstonine is an indole alkaloid extracted from the fruit of Rhazya stricta and is a selective α2-adrenoceptor antagonist. tetrahydroalstonine has shown antipsychotic activity in Rauwolfia tetraphylla. | |||
TN5204 | Uralsaponin C | Others | |
Uralsaponin C shows the cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721 with IC50 > 100 μmol/L. | |||
TN4835 | Przewalskin | HIV Protease | |
Przewalskin A and Przewalskin B showed modest anti-HIV-1 activity with EC50 = 41 and 30 microg/mL, respectively. | |||
TN5931 | Alstonic acid B | ||
Alstonic acid B is a natural product of Alstonia, Apocynaceae. The catalog number is TN5931 and the CAS number is 1159579-45-9. Alstonic acid B can be used as a reference standard. | |||
T40576 | (S)-Salsolidine | ||
(S)-Salsolidine, a chemical compound, functions as a weak inhibitor of monoamine oxidase (MAO), exhibiting an inhibition constant (K i ) of 63 μM. R enantiomer demonstrating a greater efficacy than (S)-Salsolidine, boast... | |||
TN2112 | Przewalskinic acid A | Others | |
Przewalskinic acid A is a rare, water-soluble, and highly biologically active ingredient found, thus far, only in the Salvia przewalskii Maxim herb. | |||
TN5205 | Uralsaponin D | Others | |
Uralsaponin D displayed the inhibition on the growth of cancer cells with IC50 at 18.3-41.6 μmol/L, it could significantly increase the cytotoxic activity after hydrolysis. | |||
TN6032 | Alstoyunine E | ||
Alstoyunine E shows selective inhibition of Cox-2 (>75%). | |||
T23305 | Salsolinol-1-carboxylic acid | Others | |
amino acid that occurs naturally in the CNS | |||
TN5251 | Walsuralactam A | Others | |
Walsuralactam A in the formula I, which is used as an active ingredient, and is used for treating and preventing the tumour. | |||
TN5937 | Walsuronoid B | ||
Walsuronoid B shows weak antimalarial activity. | |||
TN3399 | Alstonic acid A | Others | |
Alstonic acid A is a natural product of Alstonia, Apocynaceae. The catalog number is TN3399 and the CAS number is 1159579-44-8. Alstonic acid A can be used as a reference standard. | |||
T75527 | Chrexanthomycin C | ||
Chrexanthomycin C, an orally active marine-derived natural product, exhibits significant bioactivities and shows a binding affinity for DNA [(G4C2)4 G4] with a dissociation constant (Kd) of 2.8 mM. This compound holds po... | |||
T82822 | Brassicanate A sulfoxide | ||
Brassicanate A sulfoxide, isolated from Brassica oleracea [1], exhibits herbicidal properties by inhibiting the biosynthesis of essential amino acids in plants. It operates by binding to key enzymes such as dihydroxyacid... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01585 | SOD1 Protein, Human, Recombinant (His) | Human | E. coli |
SOD1 belongs to the Cu-Zn superoxide dismutase family. It binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmi... | |||
TMPK-00449 | HER4/ERBB4 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important... | |||
TMPK-00448 | HER4/ERBB4 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important... | |||
TMPY-03501 | Optineurin Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
OPTN (Optineurin) is a Protein Coding gene. The Optineurin gene encodes the coiled-coil containing protein optineurin. Optineurin is a multifunctional adaptor protein intimately involved in various vesicular trafficking ... | |||
TMPY-02196 | VAPB Protein, Human, Recombinant (His) | Human | E. coli |
Vesicle-associated membrane protein-associated protein B / C, also known as VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C and VAPB, is a single-pass type IV membrane protein that belongs to the VAMP-associated ... | |||
TMPJ-00654 | LGALS8 Protein, Human, Recombinant | Human | E. coli |
The Galectin family of proteins, with specificity for Nacetyllactosaminecontaining glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). They also poss... | |||
TMPH-03299 | Galectin-4/LGALS4 Protein, Rat, Recombinant | Rat | E. coli |
Galectin that binds lactose and a related range of sugars. Galectin-4/LGALS4 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 36.3 kDa and the accession number is P38... | |||
TMPH-01363 | Galectin-8/LGALS8 Protein, Human, Recombinant (GST) | Human | E. coli |
Galectin-8/LGALS8 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 62.8 kDa and the accession number is O00214. | |||
TMPH-00266 | Galectin-1/LGALS1 Protein, Bovine, Recombinant (His & SUMO) | Bovine | E. coli |
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore th... | |||
TMPJ-00021 | LGALS1 Protein, Human, Recombinant (His) | Human | E. coli |
Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domain... | |||
TMPJ-00022 | LGALS7 Protein, Human, Recombinant | Human | E. coli |
The Galectin family of proteins, with specificity for Nacetyllactosamine containing glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs).They also poss... | |||
TMPH-03296 | Galectin-3/LGALS3 Protein, Rat, Recombinant (His) | Rat | E. coli |
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute infl... | |||
TMPY-03438 | Calsequestrin 1 Protein, Human, Recombinant | Human | E. coli |
Calsequestrin-1 is an isoform of calsequestrin. Calsequestrin is a calcium-binding protein of the sarcoplasmic reticulum. It helps hold calcium in the cisterna of the sarcoplasmic reticulum after a muscle contraction,... | |||
TMPJ-00525 | LGALS14 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Galectin-14 is a member of the Galectin family of carbohydrate binding proteins. The members of Galectin family contain one or two carbohydrate recognition domains, which can bind β-Galactoside. LGALS14 is expressed intr... | |||
TMPH-03297 | LGALS3BP Protein, Rat, Recombinant (His) | Rat | E. coli |
Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. | |||
TMPJ-00563 | LGALS3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Galectin-3(LGALS3) is also known as Galactose-specific lectin 3, Mac-2 antigen, Carbohydrate-binding protein 35, Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papi... | |||
TMPH-01362 | LGALS3BP Protein, Human, Recombinant (His) | Human | E. coli |
Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. LGALS3BP Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted m... | |||
TMPH-00331 | ALS3 Protein, Candida albicans, Recombinant (B2M & His & Myc) | Candida albicans | E. coli |
Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans... | |||
TMPH-02668 | Galectin-4/LGALS4 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Galectin that binds lactose and a related range of sugars. | |||
TMPH-03298 | Galectin-4/LGALS4 Protein, Rat, Recombinant (His & SUMO) | Rat | E. coli |
Galectin that binds lactose and a related range of sugars. Galectin-4/LGALS4 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.3 ... | |||
TMPJ-01146 | LGALSL Protein, Human, Recombinant (His) | Human | E. coli |
Galectin-Related Protein (LGALSL) is a 172 amino acid protein that contains one Galectin domain. LGALSL does not appear to bind carbohydrates or lactose as the critical residues required for binding are not conserved. LG... | |||
TMPH-03230 | PHB depolymerase Protein, Ralstonia pickettii, Recombinant (His) | Ralstonia pickettii | E. coli |
This protein degrades water-insoluble and water-soluble PHB to monomeric D(-)-3-hydroxybutyrate. PHB depolymerase Protein, Ralstonia pickettii, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag... | |||
TMPH-01364 | Galectin-9/LGALS9 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Galectin-9/LGALS9 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 65.9 kDa and the accession number is O00182. |
Cat No. | Product Name | ||
---|---|---|---|
L2620 | Anti-Neurodegenerative Disease Compound Library | 2154 compounds | |
A unique collection of 2154 compounds related to neurodegenerative diseases can be used for HTS or HCS; | |||
L8710 | Cuproptosis Compound Library | 400 compounds | |
TargetMol’s Cuproptosis Compound Library is a collection of 400 compounds related to copper-dependent death that can be used to study its mechanism and related diseases. |