immunosuppressive — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2548	Diflorasone		Glucocorticoid Receptor
	Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti...		Glucocorticoid Receptor
TQ0248	Alisol F		HBV
	Alisol F is a natural product from Alisma plantago-aquatica Linn and has many activities.		HBV
T9744	MP07-66		Phosphatase
	MP07-66 is a novel FTY720-analog devoid of immunosuppressive effects leads to the reactivation of PP2A, which in turn triggers apoptosis of CLL cells.		Phosphatase
T7730	Aminopterin	APGA,4-Aminofolic acid	Antifolate
	Aminopterin (4-Aminofolic acid) is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase		Antifolate
T3603	Sodium lauryl sulfoacetate	Sodium houttuyfonate	NF-κB , MAPK
	Sodium lauryl sulfoacetate (Sodium houttuyfonate) is anti-pseudomonas agents, inhibits virulence-related motility of Pseudomonas.		NF-κB , MAPK
T7776	ADH-503	GB1275	Complement System
	ADH-503 (GB1275) is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression.		Complement System
T12399	Peldesine	BCX 34	Nucleoside Antimetabolite/Analog , HIV Protease
	Peldesine (BCX 34) is an effective, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase. Peldesine inhibits T-cell proliferation with an IC50 of 800 nM. Peldesine can be used in resear...		Nucleoside Antimetabolite/Analog , HIV Protease
T1335	Mycophenolic acid	Mycophenolate,RS-61443	Apoptosis , Dehydrogenase , Endogenous Metabolite , Antibacterial , Antibiotic , UGT , Antifungal
	Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.
T22697	CS 2100	1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid	S1P Receptor
	CS 2100 (1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid) is an S1P1 agonist.		S1P Receptor
T13379	(Z)-Leukadherin-1	ADH-503 free base	Complement System
	(Z)-Leukadherin-1 (ADH-503 free base) is an allosteric agonist of CD11b.		Complement System
T9603	MNITMT
	MNITMT is a potent immunosuppressive agent without bone marrow toxicity [1].
TQ0226	Jionoside B1		Others
	Jionoside B1 has immunosuppressive activity and shows the hepato-protective activity in the H2O2 induced liver injury experiments.		Others
T7527	Frentizole		Beta Amyloid
	Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interaction		Beta Amyloid
T1237	Azathioprine	BW 57-322	Apoptosis , GPR , Rho
	Azathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.		Apoptosis , GPR , Rho
T7202	ITE		AhR , Aryl Hydrocarbon Receptor
	ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.		AhR , Aryl Hydrocarbon Receptor
T26046	Razoxane		Topoisomerase
	Razoxane is used as an antimitotic agent with immunosuppressive properties.		Topoisomerase
TN1697	Glucosyringic acid		Immunology/Inflammation related
	Glucosyringic acid has immunosuppressive effect, it can inhibit the proliferation of murine B lymphocytes in vitro.		Immunology/Inflammation related
T16395	ONO4057	ONO-LB457	Leukotriene Receptor
	ONO4057 is a potent and orally active Leukotriene B4 receptor antagonist with an IC50 value of 0.7±0.3 μM. Immunosuppressive effect of ONO4057 on rat allografts.		Leukotriene Receptor
T5736	1,3-Dicaffeoylquinic acid	CYNARIN,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid	Reactive Oxygen Species , Akt , PI3K
	1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.		Reactive Oxygen Species , Akt , PI3K
T0707	Cyclophosphamide hydrate	Cyclophosphamide monohydrate	DNA Alkylator/Crosslinker , DNA , MRP
	Cyclophosphamide hydrate is a DNA alkylating agent, an inhibitor of DNA synthesis. Cyclophosphamide hydrate has antitumor and immunosuppressive activities.		DNA Alkylator/Crosslinker , DNA , MRP