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CS 2100

Catalog No. T22697 CAS 913827-99-3

Synonyms: 1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid

CS 2100 is an S1P1 agonist.

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CS 2100, CAS 913827-99-3

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	CS 2100 is an S1P1 agonist.
Targets&IC50	human S1P1:4.0 nM (EC50)

Synonyms	1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid
Molecular Weight	461.53
Formula	C25H23N3O4S
CAS No.	913827-99-3

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: <2 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Nakamura T, Asano M, Sekiguchi Y, et al.Synthesis and evaluation of CS-2100, a potent, orally active and S1P(3)- sparing S1P(1) agonist. Eur J Med Chem. 2012 May;51:92-8. 2. Nakamura T, Asano M, et al. Discovery of CS-2100, a potent, orally active and S1P3-sparing S1P1 agonist. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1788-92.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

CS 2100 913827-99-3 G蛋白偶联受体 S1P Receptor inhibit LPL Receptor CS2100 Inhibitor immunosuppressive efficacy HvGR CS-2100 Lysophospholipid Receptor S1P3-sparing 1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid inhibitor

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