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Mycophenolic acid

Catalog No. T1335 CAS 24280-93-1

Synonyms: Mycophenolate, RS-61443, 霉酚酸

Mycophenolic acid is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

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Mycophenolic acid, CAS 24280-93-1

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Mycophenolic acid is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

Synonyms	Mycophenolate, RS-61443, 霉酚酸
Molecular Weight	320.341
Formula	C17H20O6
CAS No.	24280-93-1

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 32 mg/mL (100 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Sintchak MD, et al. Cell, 1996, 85(6), 921-930. 2. Eugui EM, et al. Scand J Immunol, 1991, 33(2), 161-173. 3. Anderson D, et al. Mutat Res, 1995, 330(1-2), 115-181. 4. Chapuis AG, et al. Nat Med, 2000, 6(7), 762-768. 5. Zeng X, Zhu S, Lu W, et al. Target identification among known drugs by deep learning from heterogeneous networks[J]. Chemical Science. 2020, 11(7): 1775-1797.

Citations

1. Zeng X, Zhu S, Lu W, et al. Target identification among known drugs by deep learning from heterogeneous networks. Chemical Science. 2020, 11(7): 1775-1797. 2. Hu M, Wu T, Yang Y, et al. Development and Characterization of a Genetically Stable Infectious Clone for a Genotype I Isolate of Dengue Virus Serotype 1. Viruses. 2022, 14(9): 2073.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Antibiotics Library Inhibitor Library Drug-induced Liver Injury (DILI) Compound Library Natural Product Library for HTS Anti-Tumor Natural Product Library Immunology/Inflammation Compound Library Anti-Metabolism Disease Compound Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library

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Related compounds with same targets

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Mycophenolic acid 24280-93-1 代谢凋亡微生物学 Antibacterial Antibiotic Antifungal Apoptosis Dehydrogenase Endogenous Metabolite UGT dehydrogenase antitumor IMPDH inhibit Inhibitor Bacterial monophosphate antiviral Fungal RNA RS-61443 influenza Mycophenolate viruses Antiangiogenic inosine immunosuppressive inhibitor

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