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Search Result

Search Results for " eva "

Targets

Calcium Channel Adrenergic Receptor

52

Compounds

9

Natural Products

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T8143 Bevantolol hydrochloride NC-1400 hydrochloride Calcium Channel , Adrenergic Receptor
Bevantolol hydrochloride (NC-1400 hydrochloride) is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.
T15259 Evatanepag CP-533536 free acid Prostaglandin Receptor
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l...
T7164 Levalbuterol tartrate Levosalbutamol tartrate Adrenergic Receptor
Levalbuterol tartrate (Levosalbutamol tartrate) is the β2-adrenergic receptor agonist,and is used to treatment of asthma.
TQ0166 Tesevatinib KD-019,XL-647,EXEL-7647 EGFR , VEGFR , FLT , Ephrin Receptor
Tesevatinib (XL-647) is an orally available, multi-target tyrosine kinase inhibitor (IC50s: 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, Flt4, and EphB4).
T68055 Devapamil Devapamilo,Devapamilum Calcium Channel
Devapamil (Devapamilo) is a phenylalkylamine that blocks L-type calcium currents from the inner side of membrane cells in a use-dependent manner.
T0944 Levamisole hydrochloride (-)-Tetramisole hydrochloride Phospholipase , AChR , Parasite , HSV
Levamisole hydrochloride ((-)-Tetramisole hydrochloride) is an antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemo...
T9904 Bevacizumab VEGFR
Bevacizumab, a humanized monoclonal antibody, specifically and with high affinity binds to all isoforms of VEGF-A.
T0313 Evans blue Direct Blue 53,C.I. 23860 GluR
Evans blue (C.I. 23860) is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).
T4284 Levamlodipine besylate (S)-Amlodipine Besylate (103129-82-4(free base)) Calcium Channel
Levamlodipine besylate ((S)-Amlodipine Besylate (103129-82-4(free base))) , also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication. Levamlodipi...
T2405 Revaprazan hydrochloride YH1885 ATPase , COX , Antibacterial
Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.
T37596 Terevalefim c-Met/HGFR
Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.
T1545 Levamlodipine (S)-Amlodipine,S-amlodipine Calcium Channel
Levamlodipine (S-amlodipine) belongs to the dihydropyridine group of calcium channel blockers. Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and an...
T12225L Nevanimibe hydrochloride PD-132301 hydrochloride,ATR101 hydrochloride Apoptosis , Acyltransferase
Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).
T6262 Evacetrapib LY2484595 CETP
Evacetrapib (LY2484595) (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.
T25333 Dilevalol Dilevalolum
Dilevalol, the RR-stereoisomer of labetalol, is a non-cardioselective beta-adrenoceptor antagonist with substantial partial beta 2-agonist and negligible alpha 1-blocking activity.
T72531 6-Fluoromevalonate Tetrahydro-4-fluoromethyl-4-hydroxy-2H-pyran-2-one
6-Fluoromevalonate is a mevalonate-pyrophosphate decarboxylase inhibitor.
T15101 Devazepide L-364,718,MK-329 Others
Devazepide is a competitive and orally active nonpeptide antagonist of cholecystokinin (CCK) receptor (IC50s: 81 pM, 45 pM, and 245 nM for rat pancreatic, bovine gallbladder and guinea pig brain CCK receptors, respective...
T20660 Revaprazan SB-641257,SB 641257,SB641257
Revaprazan is a novel, selective potassium-competitive acid blocker, to be specific, it reversibly inhibits gastric H(+)/K(+)-ATPase and shows effective acid suppression comparable to PPIs.
T31729 Evariquinone
Evalliquinone is a biologically active isolate of Metarhizium anisopliae derived from the sponge.
T39074 (Rac)-Zevaquenabant (Rac)-MRI-1867,(Rac)-Zevaquenabant
(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of the cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), exhibiting a binding affinity (Ki) of 5.7 nM sp...
T69639 Sevasemten
Sevasemten is an allosteric inhibitor that targets skeletal muscle myosin. It displays selectivity in its inhibition, demonstrated by IC50 values of ≤10 μM for skeletal muscle myosin and >100 μM for cardiac myosin, respe...
T69755 Evatanepag sodium
Evatanepag, also known as CP-533536, is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation. CP-533536 demonstrated the ability to heal fractures when administered locally as a sin...
T34026 Phevamine A PHVA Others
Phevamine A (PHVA) is a suppressor of plant immune responses.
T68423 Revamilast sodium
Revamilast sodium, also known as GRC4039 sodium, is a phosphodiesterase IV inhibitor for potentially treating of asthma and rheumatoid arthritis
T25690 Levallorphan tartrate Lorfan
Levallorphan tartrate is an opioid antagonist with properties similar to those of NALOXONE. Levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induce...
T124525 Cevadine
T32691 Levamlodipine hydrochloride
Levamlodipine hydrochloride is a medication used to lower blood pressure and prevent chest pain.
T131536 Cevadine (Veratrine)
Cevadine (Veratrine) is a useful organic compound for research related to life sciences and the catalog number is T131536.
T28523 Revatropate UK-112 166,UK 112166,UK-112,166
Revatropate, a selective muscarinic antagonist, is an antimuscarinic drug.
T75156L Bevasiranib sodium
Bevasiranib sodium, an siRNA compound, targets and silences the genes responsible for producing vascular endothelial growth factor (VEGF). The suppression of VEGF, a critical factor in the development of choroidal neo-va...
T75156 Bevasiranib
Bevasiranib, a siRNA, is specifically engineered to suppress the expression of genes responsible for the production of vascular endothelial growth factor (VEGF), a critical factor in the development of choroidal neo-vasc...
T78287 Alsevalimab
Alsevalimab is a human monoclonal antibody targeting B7-H4 [1].
T79855 Nevadistinel NYX-458,NYX-3054 iGluR
Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, indicated for mitigating cognitive deficits related to neurodegenerative conditions, including mild cogniti...
T12225 Nevanimibe ATR-101,PD-132301 Others
Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).
T20276 Kelevan Despirol,Caswell No. 436C
Kelevan is an insecticide.
T23579 13-Hydroxystevane Kauran-13-ol
13-Hydroxystevane shows an inhibitory action on oxidative phosphorylation.
T124478 Cannabichromevarinic acid
Cannabichromevarinic acid is a useful organic compound for research related to life sciences and the catalog number is T124478.
T32690 Levallorphan Levallorphanum,Lorfan,Levallorphane,Levalorfano,Naloxiphan
Levorphane (levorphane tartrate) is an opioid modulator of the Morphan family that acts as an antagonist for μ-opioid receptor (MOR) and an agonist for κ-opioid receptor (KOR).
T61138 Bevantolol
Bevantolol, a selective β-1 adrenoceptor antagonist, is utilized for the investigation of angina pectoris and hypertension [1].
T32825 L-Mevalonic acid (S)-Mevalonic acid Others
L-Mevalonic acid ((S)-Mevalonic acid), a distant precursor of cholesterol, is a metabolite of the mevalonic acid pathway and is used in the study of autoimmune diseases, atherosclerosis and Alzheimer's disease.
T32692 Levamlodipine hydrobromide Levamlodipine HBr
Levamlodipine hydrobromide is a medication used to lower blood pressure and prevent chest pain.
T39410 Zevaquenabant (S)-MRI-1867
Zevaquenabant ((S)-MRI-1867), a dual cannabinoid CB1 receptor and inducible NOS (iNOS) antagonist, is orally bioavailable and peripherally restricted. It effectively mitigates obesity-induced chronic kidney disease (CKD)...
T34717 Stevastelin B3 NK374186B3,NK 374186B3,Antibiotic NK 374186B3,NK-374186B3
Stevastelin B3 is a depsipeptide isolated from Penicillium.
T36814 Chevalone B
Chevalone B is a meroterpenoid originally isolated from the fungus E. chevalieri. It is cytotoxic to KB and NCI-H187 cells with IC50 values of 2.9 and 9.8 μg/ml, respectively.
T75270 Genevant CL1
Genevant CL1 is a lipid that can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1] .
T71657 Evandamine
Evandamine is a Lipooxygenase Inhibitor
T20396 Levadopa Related Compound A 6-Hydroxydopa, L-,L-Hydroxydopa
Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent...
T68424 Revamilast
Revamilast, also known as GRC4039, is a phosphodiesterase IV inhibitor for potentially treating of asthma and rheumatoid arthritis
T82426 Evazarsen ISIS-757456
Evazarsen, an angiotensinogen synthesis inhibitor, exhibits antihypertensive properties [1].
T82222 H-D-MeAla-EtVaI-VaI-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVaI-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe
H-D-MeAla-EtVal-Val-MeLeu-Ala-D-Ala-MeLeu-MeLeu-MeVal-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe is a derivative of cyclosporin A lacking immunosuppressive properties with potential application in congenital muscular dystrophy resear...

Compounds

Bevantolol hydrochloride
T8143
Synonym: NC-1400 hydrochloride
Target: Calcium Channel, Adrenergic Receptor
Evatanepag
T15259
Synonym: CP-533536 free acid
Target: Prostaglandin Receptor
Levalbuterol tartrate
T7164
Synonym: Levosalbutamol tartrate
Target: Adrenergic Receptor
Tesevatinib
TQ0166
Synonym: KD-019,XL-647,EXEL-7647
Target: EGFR, VEGFR, FLT, Ephrin Receptor
Devapamil
T68055
Synonym: Devapamilo,Devapamilum
Target: Calcium Channel
Levamisole hydrochloride
T0944
Synonym: (-)-Tetramisole hydrochloride
Target: Phospholipase, AChR, Parasite, HSV
Bevacizumab
T9904
Synonym:
Target: VEGFR
Evans blue
T0313
Synonym: Direct Blue 53,C.I. 23860
Target: GluR
Levamlodipine besylate
T4284
Synonym: (S)-Amlodipine Besylate (103129-82-4(free base))
Target: Calcium Channel
Revaprazan hydrochloride
T2405
Synonym: YH1885
Target: ATPase, COX, Antibacterial
Terevalefim
T37596
Synonym:
Target: c-Met/HGFR
Levamlodipine
T1545
Synonym: (S)-Amlodipine,S-amlodipine
Target: Calcium Channel
Nevanimibe hydrochloride
T12225L
Synonym: PD-132301 hydrochloride,ATR101 hydrochloride
Target: Apoptosis, Acyltransferase
Evacetrapib
T6262
Synonym: LY2484595
Target: CETP
Dilevalol
T25333
Synonym: Dilevalolum
Target:
6-Fluoromevalonate
T72531
Synonym: Tetrahydro-4-fluoromethyl-4-hydroxy-2H-pyran-2-one
Target:
Devazepide
T15101
Synonym: L-364,718,MK-329
Target: Others
Revaprazan
T20660
Synonym: SB-641257,SB 641257,SB641257
Target:
Evariquinone
T31729
Synonym:
Target:
(Rac)-Zevaquenabant
T39074
Synonym: (Rac)-MRI-1867,(Rac)-Zevaquenabant
Target:
Sevasemten
T69639
Synonym:
Target:
Evatanepag sodium
T69755
Synonym:
Target:
Phevamine A
T34026
Synonym: PHVA
Target: Others
Revamilast sodium
T68423
Synonym:
Target:
Levallorphan tartrate
T25690
Synonym: Lorfan
Target:
Cevadine
T124525
Synonym:
Target:
Levamlodipine hydrochloride
T32691
Synonym:
Target:
Cevadine (Veratrine)
T131536
Synonym:
Target:
Revatropate
T28523
Synonym: UK-112 166,UK 112166,UK-112,166
Target:
Bevasiranib sodium
T75156L
Synonym:
Target:
Bevasiranib
T75156
Synonym:
Target:
Alsevalimab
T78287
Synonym:
Target:
Nevadistinel
T79855
Synonym: NYX-458,NYX-3054
Target: iGluR
Nevanimibe
T12225
Synonym: ATR-101,PD-132301
Target: Others
Kelevan
T20276
Synonym: Despirol,Caswell No. 436C
Target:
13-Hydroxystevane
T23579
Synonym: Kauran-13-ol
Target:
Cannabichromevarinic acid
T124478
Synonym:
Target:
Levallorphan
T32690
Synonym: Levallorphanum,Lorfan,Levallorphane,Levalorfano,Naloxiphan
Target:
Bevantolol
T61138
Synonym:
Target:
L-Mevalonic acid
T32825
Synonym: (S)-Mevalonic acid
Target: Others
Levamlodipine hydrobromide
T32692
Synonym: Levamlodipine HBr
Target:
Zevaquenabant
T39410
Synonym: (S)-MRI-1867
Target:
Stevastelin B3
T34717
Synonym: NK374186B3,NK 374186B3,Antibiotic NK 374186B3,NK-374186B3
Target:
Chevalone B
T36814
Synonym:
Target:
Genevant CL1
T75270
Synonym:
Target:
Evandamine
T71657
Synonym:
Target:
Levadopa Related Compound A
T20396
Synonym: 6-Hydroxydopa, L-,L-Hydroxydopa
Target:
Revamilast
T68424
Synonym:
Target:
Evazarsen
T82426
Synonym: ISIS-757456
Target:
H-D-MeAla-EtVaI-VaI-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVaI-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe
T82222
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
T1353 DL-Mevalonolactone Mevalonolactone Others , Endogenous Metabolite
DL-Mevalonolactone (Mevalonolactone) is very soluble in water and polar organic solvents. It exists in equilibrium with its lactone form, called mevalonolactone, that is formed by internal condensation of its terminal al...
TJP2872 Acevaltrate Acevaltratum,Acetoxyvaltrate ATPase , Others
1. Acevaltrate (Acevaltratum) displays high cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and against COLO 320, a human colorectal cancer cell line, with IC50 values of 1-6 uM.
T5722 Nevadensin Pedunculin Anti-infection , Antibacterial
Nevadensin is an important herb-based constituent inhibiting estragole bioactivation. Nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat. It also exhibits inhibition acti...
T0683 Mevastatin Compactin,ML236B Apoptosis , Antibacterial , Antibiotic , HMG-CoA Reductase , Autophagy , Lipid
Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
T36815 Chevalone C
Chevalone C is a meroterpenoid fungal metabolite originally isolated from E. chevalieri. It is active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml) and is cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml). ...
T19427 Mevalonic acid Others
Mevalonic acid is essential for cell growth and proliferation,Mevalonic acid is a precursor in the mevalonate pathway.
T22923 Levatin Others
Levatin is extracted from Croton laevigatus Vahl.
T19426 Mevalonic acid lithium salt Others
Mevalonic acid lithium salt, is essential for cell growth and proliferation.
T38478 Mevalonic acid 5-pyrophosphate tetralithium Mevalonicacid5-diphosphatetetralithium,Mevalonic acid 5-pyrophosphate tetralithium,5-Diphosphomevalonic acid tetralithium
Mevalonic acid 5-pyrophosphate (also known as 5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite involved in the mevalonate pathway.

Natural Products

DL-Mevalonolactone
T1353
Synonym: Mevalonolactone
Target: Others, Endogenous Metabolite
Acevaltrate
TJP2872
Synonym: Acevaltratum,Acetoxyvaltrate
Target: ATPase, Others
Nevadensin
T5722
Synonym: Pedunculin
Target: Anti-infection, Antibacterial
Mevastatin
T0683
Synonym: Compactin,ML236B
Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid
Chevalone C
T36815
Synonym:
Target:
Mevalonic acid
T19427
Synonym:
Target: Others
Levatin
T22923
Synonym:
Target: Others
Mevalonic acid lithium salt
T19426
Synonym:
Target: Others
Mevalonic acid 5-pyrophosphate tetralithium
T38478
Synonym: Mevalonicacid5-diphosphatetetralithium,Mevalonic acid 5-pyrophosphate tetralithium,5-Diphosphomevalonic acid tetralithium
Target:

Recombinant Proteins

Species：
Bacillus (1)
Bacillus subtilis (1)
Human (1)
Mouse (1)
Expression System：
E. coli (2)
HEK293 Cells (2)
Tag：
C-hFc (2)
N-6xHis (1)
N-6xHis-SUMO (1)
Cat No. Product Name Species Expression System
TMPK-00737 EVA-1/MPZL2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epitheli...
TMPK-00738 EVA-1/MPZL2 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epitheli...
TMPH-00163 Levanase Protein, Bacillus sp., Recombinant (His & SUMO) Bacillus E. coli
Catalyzes the hydrolysis of levan with endo-type specificity. The products of levan hydrolysis are a mixture of fructose and a series of fructooligosaccharides up to 12-mer, with levantriose being the major oligosacchari...
TMPH-00168 Levanase Protein, Bacillus subtilis, Recombinant (His) Bacillus subtilis E. coli
Exo-fructosidase that can hydrolyze both levan and inulin, leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose, but not melezitose, stachylose, cellobiose, maltos...
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