Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Mevastatin is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
Description | Mevastatin is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials. |
Targets&IC50 | HMGCR (HMG-CoA reductase:1 nM(ki) |
Synonyms | ML236B, 美伐他汀, Compactin |
Molecular Weight | 390.51 |
Formula | C23H34O5 |
CAS No. | 73573-88-3 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 72 mg/mL (184.4 mM)
Ethanol: <1 mg/mL
H2O: <1 mg/mL
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Mevastatin 73573-88-3 代谢 凋亡 微生物学 自噬 Antibacterial Antibiotic Apoptosis Autophagy HMG-CoA Reductase Lipid BMP-2 cardiovascular inhibit phosphorylation lipid-lowering neuroprotection EGFR NF-κB Statins ML236B Bacterial RANKL HMG-CoA Reductase (HMGCR) eNOS Compactin Inhibitor inhibitor