sun — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8610	sun	4H-Furo[3,2-b]pyrrole-5-carboxylic acid	Others
	Sun(4H-Furo[3,2-b]pyrrole-5-carboxylic acid) is an orally active and potent inhibitor of DAAO (DAO)		Others
T3714	SUN11602	SUN 11602	ERK , FGFR
	SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. It mimics the neuroprotective effects of bFGF and prevents glutamate-induced neuronal death. It also increases level...		ERK , FGFR
T23406	SUN B8155	SUN-B 8155	Others
	calcitonin (CT) receptor agonist		Others
T7811	Pilsicainide HCl	SUN 1165	Sodium Channel
	Pilsicainide HCl (SUN 1165) is a pure sodium channel blocker		Sodium Channel
T13040	SUN 1334H		Histamine Receptor
	SUN 1334H is a potent, orally active, highly selective antagonist of H1 receptor(Ki of 9.7 nM).		Histamine Receptor
T28884	SUN-C5174	SUNC-5174
	SUN-C5174 is a sleective 5-HT2 antagonist (pA2=8.98+/-0.06). SUN C5174 showed a marked inhibitory effect on the platelet aggregation induced by serotonin in combination with collagen and adenosine diphosphate (ADP) in ca...
T28414	Piclozotan	SUN-N-4057,SUN4057,SUNN-4057,SUN-4057,SUNN4057	5-HT Receptor
	Piclozotan (anhydrous), a 5-HT1A receptor agonist, demonstrated significant neuroprotective activity in a transient middle cerebral artery occlusion (t-MCAO) model, ameliorating motor complications in patients with advan...		5-HT Receptor
T12596	(4E)-SUN9221		5-HT Receptor , Adrenergic Receptor
	(4E)-SUN9221 is a potent dual α1-adrenergic receptor and 5-HT2 receptor antagonist that shows antihypertensive and antiplatelet aggregation activity in hypertensive rats.		5-HT Receptor , Adrenergic Receptor
T19278	Dicaprylyl carbonate	Dimethyl carbonate	Others
	Dicaprylyl carbonate (Dimethyl carbonate) is a solid fat derived from plants and a dry emollient. Dimethyl carbonate has good skin compatibility and comprehensive properties, such as a sunscreen filter with the ability t...		Others
T69727	ADA-07
	ADA-07 is a TOPK inhibitor which interacts with TOPK at the ATP-binding pocket and inhibits its kinase activity, thereby suppressing SUV-induced phosphorylation of ERK1/2, p38, and JNKs, and subsequently inhibiting AP-1 ...
T0499	Oxybenzone	KAHSCREEN BZ-3,Benzophenone 3,Eusolex 4360,Escalol 567	Apoptosis , Retinoid Receptor , Autophagy
	Oxybenzone (Eusolex 4360) is an organic compound used in sunscreens. It is a derivative of benzophenone.		Apoptosis , Retinoid Receptor , Autophagy
T9304	(S)-Sunvozertinib	N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide,DZD9008	EGFR , HER
	(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.		EGFR , HER
T0374	Sunitinib Malate	Sutent,SU 11248 (Malate),SU 11248,Sunitinib	Apoptosis , Mitophagy , VEGFR , FLT , IRE1 , PDGFR , c-Kit , Autophagy
	Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine kinase activities of VEGFR2, PDGFRβ (IC50: 80/2 nM), and c-kit.
T0433	Artesunate	WR-256283	Virus Protease , Ferroptosis , STAT , Parasite
	Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection. It is on the World Heal...		Virus Protease , Ferroptosis , STAT , Parasite
T4474	Asunaprevir	BMS-650032	HCV Protease , SARS-CoV
	Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.		HCV Protease , SARS-CoV
T64124	Sunvozertinib	DZD9008,DZD 9008,DZD-9008	EGFR , BTK
	Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor and has inhibitory effects on EGFR, Her2 and mutant epidermal growth factor. Sunvozertinib showed inhibition of EGFR exon 20 NPH insertion, EGFR exon 20 ASV ins...		EGFR , BTK
T12145L	N-Desethylsunitinib hydrochloride		VEGFR , PDGFR , c-Kit
	N-Desethylsunitinib hydrochloride is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ, and KIT inhibitor.		VEGFR , PDGFR , c-Kit
T61699	Osunprotafib	AC 484,Osunprotafib,AC484,ABBV-CLS-484	Phosphatase
	ABBV-CLS-484 (Osunprotafib) is a potent PTPN2 inhibitor with subnanomolar activity and antitumor activity that enhances T-cell anti-tumor immunity.ABBV-CLS-484 can be used for the treatment of neoplasms, esophageal cance...		Phosphatase
TN2245	Sunset Yellow FCF	Food Yellow 3,Orange Yellow S,Sunset yellow,CI 15985	Androgen Receptor
	Sunset Yellow FCF (Sunset yellow) is an orange azo dye with pH-dependent absorbance.Sunset Yellow FCF is used in food, cosmetics and pharmaceuticals.It is used as a colorant food additive in many food products.They may b...		Androgen Receptor
T0374L	Sunitinib	SU 11248	Apoptosis , Mitophagy , VEGFR , FLT , IRE1 , PDGFR , c-Kit , Autophagy
	Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM). Sunitinib has antitumor activity and can be used for the treatment of kidney cancer and ga...