simplex — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3045	Salubrinal		Apoptosis , Phosphatase , PERK , Autophagy , HSV
	Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).		Apoptosis , Phosphatase , PERK , Autophagy , HSV
T6593	ML324		Histone Demethylase , Others , HSV
	ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).		Histone Demethylase , Others , HSV
T6523	Guanosine	DL-Guanosine,Vernine,Guanozin	Endogenous Metabolite , HSV
	Guanosine (DL-Guanosine) is a purine nucleoside formed from a beta-N9-glycosidic bond between guanine and a ribose ring and is essential for metabolism.		Endogenous Metabolite , HSV
T1848	Dynasore	Dynamin Inhibitor I	Dynamin , Virus Protease , Autophagy , HSV
	Dynasore (Dynamin Inhibitor I), a cell-permeable chemical, can reversibly and non-competitivity inhibit GTPase activity of dynamin 1/2 (IC50: 15 μM in a cell-free assay). It also inhibits the mitochondrial dynamin Drp1, ...		Dynamin , Virus Protease , Autophagy , HSV
T4226	Amenamevir	ASP2151	DNA/RNA Synthesis , HSV
	Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mL).		DNA/RNA Synthesis , HSV
T0944	Levamisole hydrochloride	(-)-Tetramisole hydrochloride	Phospholipase , AChR , Parasite , HSV
	Levamisole hydrochloride ((-)-Tetramisole hydrochloride) is an antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemo...		Phospholipase , AChR , Parasite , HSV
TN1788	Isookanin		Amylase
	Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with the IC50 value of 7.9 ± 0.53 μM. Isookanin is a potent inhibitor of α-amylase (IC50=0.447 mg/ml).		Amylase
T5712	Zerumbone		Antioxidant , HSV
	Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet.It has also been shown to have anti-oxidant and anti-inflammatory activities, contributing to immunomodulatory a...		Antioxidant , HSV
T3342	Xanthohumol		Apoptosis , Others , Influenza Virus , COX , Acyltransferase , HSV
	Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated chalcones. It inhibits COX-1 and COX-2 activity and shows ...
T4051	LDC4297	LDC044297	CDK , HSV
	LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor.		CDK , HSV
T7983	Isoborneol	DL-Isoborneol	HSV
	Isoborneol (DL-Isoborneol) is a monoterpene alcohol, with neuroprotective and antiviral activities		HSV
T15280	Fiacitabine	FOAC,FIAC,NSC 382097	HSV
	Fiacitabine (NSC-382097) is a selective inhibitor of DNA replication of the herpes simplex virus(HSV) (IC50: 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively).		HSV
T0355	Valpromide	Depamide,Valpramide,Dipropylacetamide,2-propylpentanamide	Epoxide Hydrolase , HSV
	Valpromide (Dipropylacetamide) is a carboxamide derivative of valproic acid, used in the treatment of epilepsy and some affective disorders.		Epoxide Hydrolase , HSV
T16911	Sorivudine	BV-araU	DNA/RNA Synthesis
	Sorivudine (BV-araU) has antiviral activity against several viruses including varicella zoster virus, herpes simplex type 1 virus, and Epstein-Barr virus by interfering with viral DNA synthesis.		DNA/RNA Synthesis
T1454	Acyclovir	Aciclovir,Acycloguanosine	Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , HSV
	Acyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus fam...
T0895	Oxytetracycline	Terramycin	ribosome , Endogenous Metabolite , Antibacterial , Antibiotic , HSV
	Oxytetracycline (Terramycin) is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.
T6073	OG-L002		Histone Demethylase , Monoamine Oxidase , HSV
	OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.		Histone Demethylase , Monoamine Oxidase , HSV
T15394	Glyceryl monocaprate	2,3-Dihydroxypropyl decanoate,DECANOIN,Monocaprin	Antibacterial , HSV
	Glyceryl monocaprate (2,3-Dihydroxypropyl decanoate) has inhibitory effect on Herpes Simplex Virus (HSV). It also offers an effective treatment for herpes labialiss. Glyceryl monocaprate is a capric acid against 1-monogl...		Antibacterial , HSV
TQ0095	Brincidofovir	CMX001,HDP-CDV	Others , Antiviral , HSV
	Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, and orthopoxviruses.		Others , Antiviral , HSV
T6062	Brefeldin A	BFA,Ascotoxin,Cyanein,Decumbin	ATPase , Mitophagy , Antibiotic , Autophagy , HSV , CRISPR/Cas9
	Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM). Brefeldin A can induce tumor cell differentiation and apoptosis, and also possesses autophagy inhibitory activ...