Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Oxytetracycline (Terramycin) is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 36.00 | |
50 mg | In stock | $ 46.00 | |
100 mg | In stock | $ 64.00 | |
200 mg | In stock | $ 108.00 | |
500 mg | In stock | $ 178.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | Oxytetracycline (Terramycin) is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions. |
In vivo | Oxytetracycline (200 mg/kg for 15 days) results a significant elevation in serum hepatospecific markers such as aspartate transaminase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, and bilirubin and the levels of lipid peroxidation markers (thiobarbituric acid reactive substances (TBARS) and lipid hydroperoxides) in rat liver. Oxytetracycline also causes a significant reduction in the activities of superoxide dismutase, catalase, glutathione peroxidase, reduced glutathione (GSH), vitamin C and vitamin E in rat liver. Oxytetracycline (200 mg/kg) combined with Naringenin (50 mg/kg b.w.t.) significantly decreases the activities of serum aspartate transaminase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase and the levels of bilirubin along with significant decrease in the levels of lipid peroxidation markers in the rat liver. [1] Oxytetracycline (200 mg/kg, oral for 15 days) produces hepatic damage as manifested by a significant increase in serum hepatic markers namely aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), bilirubin and increases plasma and hepatic lipid peroxidation indices (TBARS and hydroperoxide) in rats. Oxytetracycline significantly decreases the levels of enzymatic antioxidants namely superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx). [2] |
Synonyms | Terramycin |
Molecular Weight | 460.43 |
Formula | C22H24N2O9 |
CAS No. | 79-57-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 85 mg/mL (184.6 mM)
Ethanol: 10 mg/mL (21.71 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Oxytetracycline 79-57-2 Metabolism Microbiology/Virology ribosome HSV Antibiotic Endogenous Metabolite Antibacterial Gram-positive protein HSV-1 synthesis tetracycline Herpes simplex virus inhibit m-ribosomal Gram-negative Bacterial Inhibitor Terramycin aminoacil-tRNA inhibitor