Search Result

Search Results for " camk "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T14860	CaMKII-IN-1		CaMK , Autophagy
	CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor (IC50: 63 nM). It has significantly high selectivity against CaMKIV, p38a, MLCK, Akt1, and PKC.		CaMK , Autophagy
TQ0137	A-484954	A 484954	CaMK , Parasite , Autophagy
	A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.		CaMK , Parasite , Autophagy
T2697	KN-93		CaMK , Autophagy
	KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.		CaMK , Autophagy
TP2310	Autocamtide-2-related inhibitory peptide		CaMK , Autophagy
	Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.		CaMK , Autophagy
T6605	NH125		CaMK , Virus Protease , PKA , Antibacterial , PKC , Autophagy , Antifungal
	NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.
T2694	KN-62		CaMK , P2X Receptor , Autophagy
	KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.		CaMK , P2X Receptor , Autophagy
T3546	STO-609	STO 609	CaMK , AMPK , Autophagy
	STO-609 is a specific and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK) for recombinant CaM-KKα/KKβ (Ki: 80/15 ng/mL).		CaMK , AMPK , Autophagy
T10667	Calmidazolium chloride	R 24571	CaMK , Autophagy
	Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist (Kd = 3 nM), antagonizing CaM-dependent phosphodiesterase(IC50 = 0.15 μM) and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase(IC50 ...		CaMK , Autophagy
T8389	Trifluoperazine	trifluoroperazine	CaMK , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , P-gp , Autophagy
	Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.
T14069	A-3 hydrochloride		CaMK , Casein Kinase , PKA , PKC
	A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectiv...		CaMK , Casein Kinase , PKA , PKC
T4185	Lavendustin C	HDBA,NSC 666251	CaMK , EGFR , Tyrosinase , Src
	lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.		CaMK , EGFR , Tyrosinase , Src
T1222	Trifluoperazine dihydrochloride	Trifluoperazine 2HCl,SKF5019,Urinox	CaMK , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , P-gp , Autophagy
	Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.
T2159	CaMKP Inhibitor		CaMK
	CaMKP Inhibitor can inhibit CaMKP.		CaMK
T79718	CaMKIIα-PHOTAC		CaMK
	CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα). This molecule facilitates the ubiquitination and subsequent proteasome-medi...		CaMK
T60515	CaMKIIα-IN-1
	CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub. CaMKIIα-IN-1 shows good metabolic stability [1].
T2606	KN-93 Phosphate		CaMK
	KN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II with K i of 370 nM. KN-93 phosphate inhibits serum-induced fibroblast cell growth in a comparable dose-dependent fashion to it...		CaMK
T3935	1-Naphthyl PP1	1-NA-PP 1	Src
	1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)		Src
T4444	A-674563 HCl (552325-73-2(free base))		ERK , Akt , PKA , CDK , PKC
	A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 (IC50: 16/46 nM) but is 10- to >1, 800-fold selective for A...		ERK , Akt , PKA , CDK , PKC
T7371	1-Naphthyl PP1 hydrochloride	1-NA-PP 1 hydrochloride	Src
	1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-Src		Src
TP1216	CaM kinase II inhibitor TFA salt	Autocamtide-2-related inhibitory peptide (TFA)	CaMK
	CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide (TFA)) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.		CaMK
TP1271L	Calmodulin-Dependent Protein Kinase II 290-309 acetate	Calmodulin-Dependent Protein Kinase II 290-309 acetate (115044-69-4 Free base)	CaMK
	Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).		CaMK
T4530	KN-92 phosphate	KN92-H3PO4	CaMK
	KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM).		CaMK
TP1829	Autocamtide 2, amide
	Autocamtide 2, amide is a substrate (100 μM final concentration) for CaMK family assays.Autocamtide-2 Peptide is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), a member ...
T13384L	Y-33075 dihydrochloride		CaMK , ROCK , PKC
	Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).		CaMK , ROCK , PKC
T76408	Autocamtide-3
	Autocamtide-3, a selective substrate for CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK), comprises a 13-amino-acid peptide featuring Thr287 [1].
T75959	Calmodulin-Dependent Protein Kinase II(290-309) acetate
	Calmodulin-Dependent Protein Kinase II (290-309) acetate is a potent antagonist of CaMK, exhibiting an IC50 of 52 nM for the inhibition of Ca2+/calmodulin-dependent protein kinase II [1].
TP1271	Calmodulin-Dependent Protein Kinase II (290-309)	Calmodulin-Dependent Protein Kinase II(290-309)
	Calmodulin-Dependent Protein Kinase II (290-309) is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II.
T76488	Calmodulin Dependent Protein Kinase Substrate
	Calmodulin Dependent Protein Kinase Substrate is a synthetic peptide that serves as a substrate for protein kinases and requires calcium ions (Ca 2+) and calmodulin (CaM) for activation. It specifically interacts with ca...
TP1217	Autocamtide 2	Autocamtide II
	Autocamtide-2 is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family.
T73247	PIM1-IN-4		Pim
	PIM1-IN-4 (Compound 8) is a potent PIM1 inhibitor with significant inhibitory activity against five additional enzymes: SGK-1, PKA, CaMK-1, GSK3β, and MSK1, rendering it a potentially useful agent for cancer research [1]...		Pim
TQ0319	Ripasudil	K-115,Ripasudil hydrochloride dihydrate	ROCK
	Ripasudil (Ripasudil hydrochloride dihydrate) (K-115) hydrochloride dihydrate is a specific ROCK inhibitor (IC50s: 51/19 nM for ROCK1/ROCK2).		ROCK
T76487	Calmodulin Dependent Protein Kinase Substrate Analog
	Calmodulin-Dependent Protein Kinase Substrate Analog, a synthetic peptide substrate, is activated by Ca2+ and calmodulin (CaM). It serves as a substrate for protein kinases, leveraging a dependency on Ca2+ and CaM for it...
T35328	H-1152 dihydrochloride	H-1152 2HCl,H-1152 dihydrochloride	ROCK
	H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 ...		ROCK
T16752	Rimacalib	SMP 114	CaMK
	Rimacalib is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (IC50s: ~1 μM for CaMKIIα and ~30 μM for CaMKIIγ).		CaMK
T13384	Y-33075	Y 39983	PKC
	Y-33075 is a selective inhibitor of ROCK derived from Y-27632, and is more potent than Y-27632, with an IC50 of 3.6 nM.		PKC
T35459	Glycyl H-1152 hydrochloride
	Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and prol...
T7492	Ripasudil free base	K-115 (free base)	ROCK , Antibacterial
	Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent.		ROCK , Antibacterial

Compounds

CaMKII-IN-1

T14860

Synonym:

Target: CaMK, Autophagy

A-484954

TQ0137

Synonym: A 484954

Target: CaMK, Parasite, Autophagy

KN-93

T2697

Synonym:

Target: CaMK, Autophagy

Autocamtide-2-related inhibitory peptide

TP2310

Synonym:

Target: CaMK, Autophagy

NH125

T6605

Synonym:

Target: CaMK, Virus Protease, PKA, Antibacterial, PKC, Autophagy, Antifungal

KN-62

T2694

Synonym:

Target: CaMK, P2X Receptor, Autophagy

STO-609

T3546

Synonym: STO 609

Target: CaMK, AMPK, Autophagy

Calmidazolium chloride

T10667

Synonym: R 24571

Target: CaMK, Autophagy

Trifluoperazine

T8389

Synonym: trifluoroperazine

Target: CaMK, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, P-gp, Autophagy

A-3 hydrochloride

T14069

Synonym:

Target: CaMK, Casein Kinase, PKA, PKC

lavendustin C

T4185

Synonym: HDBA,NSC 666251

Target: CaMK, EGFR, Tyrosinase, Src

Trifluoperazine dihydrochloride

T1222

Synonym: Trifluoperazine 2HCl,SKF5019,Urinox

Target: CaMK, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, P-gp, Autophagy

A-674563 HCl (552325-73-2(free base))

T4444

Synonym:

Target: ERK, Akt, PKA, CDK, PKC

1-Naphthyl PP1 hydrochloride

T7371

Synonym: 1-NA-PP 1 hydrochloride

Target: Src

CaM kinase II inhibitor TFA salt

TP1216

Synonym: Autocamtide-2-related inhibitory peptide (TFA)

Target: CaMK

Calmodulin-Dependent Protein Kinase II 290-309 acetate

TP1271L

Synonym: Calmodulin-Dependent Protein Kinase II 290-309 acetate (115044-69-4 Free base)

Y-33075 dihydrochloride

T13384L

Synonym:

Target: CaMK, ROCK, PKC

Calmodulin-Dependent Protein Kinase II(290-309) acetate

T75959

Synonym:

Target:

Calmodulin-Dependent Protein Kinase II (290-309)

TP1271

Synonym: Calmodulin-Dependent Protein Kinase II(290-309)

Target:

Calmodulin Dependent Protein Kinase Substrate

Synonym: Autocamtide II

Synonym: K-115,Ripasudil hydrochloride dihydrate

Target: ROCK

Calmodulin Dependent Protein Kinase Substrate Analog

T76487

Synonym:

Target:

H-1152 dihydrochloride

T35328

Synonym: H-1152 2HCl,H-1152 dihydrochloride

Glycyl H-1152 hydrochloride

Synonym: K-115 (free base)

Target: ROCK, Antibacterial

Cat No.	Product Name	Synonyms	Targets
T15636	K-252a	Antibiotic K 252a,Antibiotic SF 2370,SF2370	Others
	K-252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi. K-252a inhibits protein kinase (IC50: 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphoryla...		Others

Natural Products

K-252a

T15636

Synonym: Antibiotic K 252a,Antibiotic SF 2370,SF2370

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04543	CAMKIV Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	CAMKIV Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 79 kDa and the accession number is Q16566.
TMPH-01027	CAMK2D Protein, Human, Recombinant (His)	Human	E. coli
	CAMK2D Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 63.1 kDa and the accession number is Q13557.
TMPY-04408	CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. CaMKII is an important player in pro...
TMPJ-00240	CAMK1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed....
TMPY-04423	CAMKI gamma/CAMK1G Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Calmodulin-Dependent Protein Kinase (CaM Kinase) is a kind of protein phosphorylate multiple downstream targets. Concentration of cytosolic calcium functions as a second messenger that mediates a wide range of cellular r...
TMPY-04566	CAMKV Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	CaM kinase-like vesicle-associated protein, also known as CAMKV, is a peripheral membrane protein and Cytoplasmic vesicle membrane protein which belongs to theprotein kinase superfamily and CAMK Ser/Thr protein kinase...
TMPY-04373	CAMKII alpha/CAMK2A Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Ca2+/calmodulin-dependent protein kinase2A (CAMK2A) belongs to the serine/threonine protein kinase family and, together with other 28 different isoforms, belongs to the Ca2+/ calmodulin-dependent protein kinase subfamily...
TMPY-04759	CAMKIV Protein, Mouse, Recombinant	Mouse	Baculovirus Insect Cells
	CAMKIV Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 52.7 kDa and the accession number is P08414.
TMPY-04381	CAMK1D Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	CAMK1D Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 69 kDa and the accession number is Q8IU85-1.
TMPY-04415	CAMKI Protein, Human, Recombinant	Human	E. coli
	CAMKI Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 41.5 kDa and the accession number is B0YIY3.
TMPY-04573	CAMKIV Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	CAMKIV Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 80.4 kDa and the accession number is P08414.
TMPH-01026	CAMK2N1 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	Potent and specific inhibitor of CaM-kinase II (CAMK2). CAMK2N1 Protein, Human, Recombinant (His & Trx) is expressed in E. coli expression system with N-6xHis-Trx tag. The predicted molecular weight is 25.6 kDa and the a...
TMPY-04406	Protein Kinase D2/PRKD2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Serine/threonine-protein kinase D2, also known as PRKD2 and PKD2, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD2 / PKD2 is ...
TMPY-04557	PHKG1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform, also known as Phosphorylase kinase subunit gamma-1 and PHKG1, is a member of the protein kinase superfamily and CAMK Ser/Thr protein kinase family. P...
TMPY-04471	APEG1 Protein, Human, Recombinant (His)	Human	E. coli
	Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr pr...
TMPY-04425	PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated...
TMPY-04417	DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)	Human	Baculovirus Insect Cells
	Death-associated protein kinase 1, also known as DAP kinase 1, DAPK1 and DAPK, is a cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser / Thr protein kinase family and DAP kinase subfamily. DAPK...
TMPY-04385	ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP ...
TMPY-04461	TRIB3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Tribbles homolog 3, also known as Neuronal cell death-inducible putative kinase, p65-interacting inhibitor of NF-kappa-B, SINK and TRIB3, is a Nucleus protein that belongs to the protein kinase superfamily and CAMK Ser/T...
TMPY-04456	PKC nu Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Serine/threonine-protein kinase D3, also known as Protein kinase C nu type, Protein kinase EPK2, PRKD3, EPK2 and PRKCN, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr pro...