Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist (Kd = 3 nM), antagonizing CaM-dependent phosphodiesterase(IC50 = 0.15 μM) and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase(IC50 = 0.35 μM). Calmidazolium chloride also induces apoptosis in certain cancer cell lines.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 57.00 | |
10 mg | In stock | $ 89.00 | |
25 mg | In stock | $ 148.00 | |
50 mg | In stock | $ 226.00 | |
100 mg | In stock | $ 337.00 | |
200 mg | In stock | $ 491.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 87.00 |
Description | Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist (Kd = 3 nM), antagonizing CaM-dependent phosphodiesterase(IC50 = 0.15 μM) and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase(IC50 = 0.35 μM). Calmidazolium chloride also induces apoptosis in certain cancer cell lines. |
Targets&IC50 | calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase:0.35 μM, calmodulin:8.18 μM(mouse F9 ECCs), calmodulin:3 nM(kd), calmodulin:12.69 μM(mouse E14 ESCs), CaM-dependent phosphodiesterase:0.15 μM |
In vitro | Calmidazolium chloride also induces apoptosis in certain cancer cell lines. Calmidazolium chloride (3, 5, 7, 10 μM, 30 minutes-24 hours) inhibits the growth of mouse F9 ECCs [2]. |
Synonyms | R 24571 |
Molecular Weight | 687.7 |
Formula | C31H23Cl7N2O |
CAS No. | 57265-65-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (145.41 mM)
You can also refer to dose conversion for different animals. More
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