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lavendustin C

Catalog No. T4185 CAS 125697-93-0

Synonyms: HDBA, NSC 666251

lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.

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lavendustin C, CAS 125697-93-0

Pack Size	Availability	Price/USD
1 mg	In stock	$ 37.00
2 mg	In stock	$ 53.00
5 mg	In stock	$ 89.00
10 mg	In stock	$ 163.00
25 mg	In stock	$ 367.00
50 mg	In stock	$ 546.00
100 mg	In stock	$ 786.00
1 mL * 10 mM (in DMSO)	In stock	$ 87.00

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Purity: 97.77%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.
Targets&IC50	EGFR:0.012 μM (IC50), CaMK II:0.2 μM (IC50)

Synonyms	HDBA, NSC 666251
Molecular Weight	275.26
Formula	C14H13NO5
CAS No.	125697-93-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/mL (217.98 mM)

References and Literature

1. Nynca A, et al. Effects of the phytoestrogen, genistein, and protein tyrosine kinase inhibitor-dependent mechanisms on steroidogenesis and estrogen receptor expression in porcine granulosa cells of medium follicles. Domest Anim Endocrinol. 2013 Jan;44(1):10-8 2. Kobayashi T,et al. Involvement of CaM kinase II in the impairment of endothelial function and eNOS activity in aortas of Type 2 diabetic rats. Clin Sci (Lond). 2012 Sep;123(6):375-86 3. Opałka M, etal. Genistein affects testosterone secretion by Leydig cells in roosters (Gallus gallus domesticus). Reprod Biol. 2004 Jul;4(2):185-93.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Membrane Protein-targeted Compound Library Kinase Inhibitor Library Tyrosine Kinase Inhibitor Library Anti-Cancer Metabolism Compound Library Reprogramming Compound Library Angiogenesis related Compound Library Bioactive Compound Library Anti-Breast Cancer Compound Library Anti-Pancreatic Cancer Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

lavendustin C 125697-93-0 Angiogenesis JAK/STAT signaling Neuroscience Proteases/Proteasome Tyrosine Kinase/Adaptors Tyrosinase Src CaMK EGFR HER1 ErbB-1 HDBA inhibit NSC 666251 Inhibitor Calmodulin-dependent protein kinases calmodulin-dependent NSC-666251 pp60 Ca2+ Epidermal growth factor receptor tyrosine kinase NSC666251 Calmodulin-dependent kinases inhibitor

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