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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2S1200 | Sinapine | Antioxidant , P-gp , AChE | |
1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant and radio-protective activities. | |||
T3392 | Sinapine thiocyanate | P-gp , AChE | |
Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds. It is the choline ester of Sinapic Acid (S486800). It is also a phenolic-chloine conjugates, acting as anti-o... | |||
T0724 | Formononetin | Biochanin B,Flavosil,Formononetol | Apoptosis , FGFR |
Formononetin (Flavosil) is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus. | |||
T3803 | Specnuezhenide | Nuzhenide,Nuezhenide | Others , NF-κB , Wnt/beta-catenin |
Specnuezhenide (Nuezhenide) significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.Nuezhenide is the main inhibitory compound of fruits, it shows a clear inhibitory effect t... | |||
T8616 | Fasentin | N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide | transporter |
Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1. | |||
T2961 | Notoginsenoside R1 | Sanqi glucoside R1,Sanchinoside R1 | Apoptosis , ERK , Beta Amyloid |
Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties. | |||
T7541 | PTP inhibitor 1 | PTP Inhibitor II | Phosphatase |
PTP inhibitor 1 is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)),with Ki of128 μM. | |||
T8846 | Beta-Escin | B-escin,AESCINE | Immunology/Inflammation related |
beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent. | |||
T2160 | Suramin Sodium Salt | BAY-205,Suramin hexasodium salt,NF-060 | Apoptosis , Phosphatase , SARS-CoV , Sirtuin , Reverse Transcriptase , Topoisomerase , Parasite |
Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth f... | |||
T7057 | Methylstat | Histone Demethylase , Others | |
Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability. The free acid of methylstat inhibits JMJD2A, JMJD2C, JMJD2E, PHF8, and JMJD... | |||
T24804 | SM27 | SM-27,NSC-37204,SM 27,NSC37204 | FGFR |
SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours. | |||
T28911 | Tafetinib | SIM-010603,SIM010603,SIM 010603 | Tyrosine Kinases |
Tafetinib (SIM-010603) is a novel potent and orally available tyrosine kinase inhibitor with anti-angiogenic and anti-tumour activity. | |||
T5726 | Specneuzhenide | Nuezhenide | Others |
Specneuzhenide (Nuezhenide) is a phenol glycoside isolated from Ligustrum sinense. Specneuzhenide (Nuezhenide) possesses anti-tumor activity,has anti-angiogenic and vision improvement effects. | |||
T12644L | (S)-Thalidomide | (S)-(-)-Thalidomide | Apoptosis |
(S)-Thalidomide ((S)-(-)-Thalidomide) is the S-isomer of Thalidomide with immunomodulatory, anti-inflammatory, anticancer, anti-angiogenic and pro-apoptotic activities, and is used in the study of leprosy erythema nodosu... | |||
T2883 | Syringic acid | 3,5-dimethyl ether Gallic Acid,SYRA,3,5-dimethoxy-4-hydroxy Benzoic Acid,NSC 2129 | Others , Endogenous Metabolite , Antibacterial |
Syringic acid (3,5-dimethoxy-4-hydroxy Benzoic Acid) (SYRA) is a potential antioxidant used in traditional Chinese medicine and is an emerging nutraceutical. It has potential anti-angiogenic, anti-glycating, anti-hypergl... | |||
T6279L | Givinostat hydrochloride | ITF2357 hydrochloride,Givinostat HCl,ITF2357,ITF 2357,ITF-2357,ITF2357 HCl | HDAC |
Givinostat hydrochloride (ITF2357 hydrochloride) is an inhibitor of HDAC with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat hydrochloride exhibits anti-inflammatory, anti-angiogenic, and antineopla... | |||
T36712 | BPHA | MMP-2/MMP-9 Inhibitor II | MMP |
BPHA (MMP-2/MMP-9 Inhibitor II) is a potent, selective and orally active inhibitor of MMP-2, MMP-9 and MMP-14 with IC50s of 12 nM, 16 nM and 17 nM, respectively.BPHA does not inhibit MMP-1, -3 and -7 (IC50s of 974, >1000... | |||
T5648 | Purpurin | 1,2,4-Trihydroxyanthraquinone,Hydroxylizaric acid,Verantin | MAO , Antibacterial , Antibiotic , Antifungal |
Purpurin (Verantin) was a reversible and competitive inhibitor of MAO-A with a Ki value of 0.422μM. it exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities. | |||
T77728 | Tubulin polymerization-IN-55 | Microtubule Associated | |
Tubulin polymerization-IN-55 is a potent Tubulin Polymerization inhibitor with potential anti-angiogenic and anti-tumour activity, showing anti-proliferative effects against A549, K562, HepG2, MDA-MB-231 and HFL-1. | |||
T0213 | Thalidomide | Thalomid,Sedoval | Apoptosis , TNF , Autophagy , Ligand for E3 Ligase , Molecular Glues |
Thalidomide (Thalomid) is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties. |