Search Result

Search Results for " rg1 "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T10616	BRM/BRG1 ATP Inhibitor-1		Epigenetic Reader Domain
	BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50...		Epigenetic Reader Domain
T3545	RG13022	RG 13022,Tyrphostin RG13022	EGFR
	RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).		EGFR
T3554	RG14620	Tyrphostin RG14620,RG 14620	EGFR , HER
	RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.		EGFR , HER
T2038	RG108	N-Phthalyl-L-tryptophan	DNA Methyltransferase
	RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).		DNA Methyltransferase
T78525	IRG1-IN-1		Others
	IRG1-IN-1 is an itaconic acid derivative with the ability to inhibit the activity of Immune Response Gene 1 (IRG1) and is suitable for use in the field of cancer, inflammation and autoimmune disease research.		Others
T60032	BRM/BRG1 ATP Inhibitor-2		Epigenetic Reader Domain
	BRM/BRG1 ATP Inhibitor-2 is an inhibitor of BRG1/BRM ATPase and can be used in studies about the treatment of BAF-related disorders.		Epigenetic Reader Domain
TP1931L1	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base)	cholecystokinin
	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) is a broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist ...		cholecystokinin
T76446	(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P
	(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P is a selective NK 1 receptor antagonist [1] .
T60870	BRG1-IN-1
	BRG1-IN-1 (Compound 11d) is a potent BRG1 inhibitor with better efficacy than PFI-3 in sensitizing GBM cells to the antiproliferative and cell death inducing effects of Temozolomide in vitro. BRG1-IN-1 enhances the inhib...
T75896	[Arg14,Lys15]Nociceptin TFA
	[Arg14,Lys15]Nociceptin TFA is a potent and selective agonist for the NOP receptor (ORL1; OP4), exhibiting an EC50 of 1 nM. It demonstrates significant selectivity against opioid receptors, with IC50 values of 0.32 nM fo...
TP1931	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
	Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradyki...
TP1986	[Arg14,Lys15]Nociceptin
	Highly potent and selective NOP receptor agonist (EC50 = 1 nM). Displays > 875-fold selectivity over opioid receptors (IC50 values are 0.32, 280, > 10000 and 1500 for NOP, μ, δ and κ receptors respectively). Longer lasti...
T83195	Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27)
	Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP(1-7)-GRF(8-27) is a selective antagonist [1] for the vasoactive intestinal peptide 1 (VIP 1) receptor.
T83500	[Des-Arg10]-HOE I40
	[Des-Arg10]-HOE 140 is a bioactive peptide that functions as a potent B1 bradykinin receptor antagonist.
T83548	(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate
	(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate), an antagonist for Substance P and Bombesin, modulates ocular inflammatory responses triggered by antidromic trigeminal nerve stimulation [1].
T78656	ARG1-IN-1 hydrochloride		Arginase
	ARG1-IN-1 hydrochloride is a potent inhibitor of human arginase 1, exhibiting an IC50 value of 29 nM [1].		Arginase
T72257	BRM/BRG1 ATP Inhibitor-3
	BRM/BRG1 ATP Inhibitor-3 is a potent inhibitor targeting both BRM and BRG1 components of the BAF complex, exhibiting IC50 values of 10.4 nM for BRM and 19.3 nM for BRG1, respectively. It holds potential for research appl...
T83690	[Leu144, Arg147]-PLP (139-151) TFA	[Leu144, Arg147] Proteolipid Peptide (139-151),H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH
	[Leu144,Arg147]-PLP (139-151) is a mutated fragment of the myelin proteolipid protein (PLP), featuring substitutions of tryptophan to leucine and histidine to arginine at positions 144 and 147, respectively. Immunizing m...
T72258	BRM/BRG1 ATP Inhibitor-4
	BRM/BRG1 ATP Inhibitor-4, a potent inhibitor of BRG1/BRM, is utilized in the research of cancers and BAF complex-related disorders.
T76445	(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P
	(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P is a neuropeptide Substance P antagonist [1] .
T39932	ARG1-IN-1	ARG1-IN-1
	ARG1-IN-1 is a human arginase 1 inhibitor with an IC 50 of 29 nM.

Compounds

BRM/BRG1 ATP Inhibitor-1

T10616

Synonym:

Target: Epigenetic Reader Domain

RG13022

T3545

Synonym: RG 13022,Tyrphostin RG13022

Target: EGFR

RG14620

T3554

Synonym: Tyrphostin RG14620,RG 14620

Target: EGFR, HER

RG108

T2038

Synonym: N-Phthalyl-L-tryptophan

Target: DNA Methyltransferase

BRM/BRG1 ATP Inhibitor-2

T60032

Synonym:

Target: Epigenetic Reader Domain

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate

TP1931L1

Synonym: [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base)

Target: cholecystokinin

(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P

[Arg14,Lys15]Nociceptin TFA

T75896

Synonym:

Target:

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P

TP1931

Synonym:

Target:

[Arg14,Lys15]Nociceptin

TP1986

Synonym:

Target:

Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27)

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate

T83548

Synonym:

Target:

ARG1-IN-1 hydrochloride

T78656

Synonym:

Target: Arginase

BRM/BRG1 ATP Inhibitor-3

T72257

Synonym:

Target:

[Leu144, Arg147]-PLP (139-151) TFA

T83690

Synonym: [Leu144, Arg147] Proteolipid Peptide (139-151),H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH

Target:

BRM/BRG1 ATP Inhibitor-4

T72258

Synonym:

Target:

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P

Cat No.	Product Name	Synonyms	Targets
T2777	Ginsenoside Rg1	Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,Panaxoside A,Ginsenoside A2	Apoptosis , Beta Amyloid , NF-κB
	Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng). It improves spatial learning and increase hippocampal synaptophysin level i...		Apoptosis , Beta Amyloid , NF-κB
T3401	Ginsenoside F1	20(S)-Ginsenoside F1	P450 , Endogenous Metabolite
	Ginsenoside F1 (20(S)-Ginsenoside F1) is an enzymatically modified derivative of ginsenoside Rg1, showing competitive inhibition of the activity of CYP3A4 and a weaker inhibition of the activity of CYP2D6.		P450 , Endogenous Metabolite
T3917	Protopanaxatriol	20(R)-APPT,20(R)-Protopanaxatriol,(20R)-Protopanaxatriol	PPAR
	Protopanaxatriol (20(R)-APPT), a major ginseng constituent, is a novel PPARγ antagonist.		PPAR

Natural Products

Ginsenoside Rg1

T2777

Synonym: Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,Panaxoside A,Ginsenoside A2

Target: Apoptosis, Beta Amyloid, NF-κB

Ginsenoside F1

T3401

Synonym: 20(S)-Ginsenoside F1

Target: P450, Endogenous Metabolite

Protopanaxatriol

T3917

Synonym: 20(R)-APPT,20(R)-Protopanaxatriol,(20R)-Protopanaxatriol

Target: PPAR

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-01246	GDF-15 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-01243	GDF-15 Protein, Rat, Recombinant (His)	Rat	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GD...
TMPK-01245	GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated	Mouse	HEK293
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00663	GDF-15 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00664	GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated	Cynomolgus	HEK293
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00198	GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated	Human	HEK293
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00197	GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated	Human	HEK293
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-01244	GDF-15 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00569	GDF-15 Protein, Canine, Recombinant (His)	Canine	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GD...
TMPK-00665	GDF-15 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00196	GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GD...
TMPY-04018	LRG1 Protein, Human, Recombinant	Human	HEK293
	LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell...
TMPY-02168	Arginase 1/ARG1 Protein, Human, Recombinant (His)	Human	HEK293
	Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxid...
TMPH-02064	SCRG1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	SCRG1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-03965	LRG1 Protein, Human, Recombinant (hFc)	Human	HEK293
	LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell...
TMPY-00479	Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-04237	Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His)	Canine	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPK-01128	LRG1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Diabetic nephropathy (DN) is an important public health concern of increasing proportions and the leading cause of end-stage renal disease (ESRD) in diabetic patients. It is one of the most common long-term microvascular...
TMPK-00750	KLRG1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Immune homeostasis requires the tight, tissue-specific control of the different CD4 Foxp3 regulatory T (Treg) cell populations. The cadherin-binding inhibitory receptor killer cell lectin-like receptor G1 (KLRG1) is expr...
TMPY-04685	Arginase 1/ARG1 Protein, Human, Recombinant (His & MYC)	Human	HEK293
	Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxid...
TMPJ-00448	NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)	Human	E. coli
	Pro-neuregulin-1,Neuregulin-1 beta 1（NRG1） is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig-like C2-type (immunoglobulin-like) domain. Direct ligand f...
TMPH-02887	SCRG1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	SCRG1 Protein, Mouse, Recombinant (His) is expressed in E. coli.
TMPH-02524	Arginase-1/ARG1 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ...
TMPH-03447	ERG11 Protein, S. cerevisiae, Recombinant (GST)	Saccharomyces cerevisiae	E. coli
	Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
TMPH-02525	Arginase-1/ARG1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ...
TMPY-03601	PDRG1 Protein, Human, Recombinant (His)	Human	E. coli
	PDRG1, also known as C2orf126, belongs to the prefoldin subunit beta family. It is predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. PDRG1 may play a role in chapero...
TMPY-03902	Neuregulin-1/NRG1 Protein, Canine, Recombinant (mFc)	Canine	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-04690	Influenza A H3N2 (A/Netherlands/178/1995 (RG145K)) Hemagglutinin/HA Protein (His)	H3N2	Baculovirus-Insect Cells
	The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two...
TMPY-02721	NRG1 alpha Protein, Human, Recombinant (His)	Human	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-03010	NRG1 beta 1 Protein, Human, Recombinant	Human	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-02705	NRG1 beta 1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-03943	Neuregulin-1/NRG1 Protein, Canine, Recombinant (hFc)	Canine	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-02719	NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc)	Human	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPK-01140	KLRG1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Immune homeostasis requires the tight, tissue-specific control of the different CD4 Foxp3 regulatory T (Treg) cell populations. The cadherin-binding inhibitory receptor killer cell lectin-like receptor G1 (KLRG1) is expr...
TMPJ-00231	LRG1 Protein, Human, Recombinant (hFc & His)	Human	Human Cells
	LRG1 is a secreted protein and contains eight LRR repeats and one LRRCT domain, It can be expressed during granulocyte differentiation. LRG1 has been shown to be involved in protein-protein interaction, signal transducti...
TMPY-04603	Influenza A H3N2 (A/Netherlands/178/1995 (RG145K)) Hemagglutinin/HA1 Protein (His)	H3N2	HEK293
	The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two...
TMPY-05813	Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated	Human	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-04088	Neuregulin-1/NRG1 Protein, Canine, Recombinant	Canine	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-03443	NDRG1 Protein, Human, Recombinant (His)	Human	E. coli
	NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differ...
TMPY-03966	LRG1 Protein, Human, Recombinant (His)	Human	HEK293
	LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell...
TMPY-03903	Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 19-240, His)	Canine	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-02600	NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)	Human	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-02720	NRG1 alpha Protein, Human, Recombinant (hFc)	Human	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-00031	Neuregulin-1/NRG1 Protein, Human, Recombinant (His)	Human	HEK293
	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPK-00526	LRG1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Diabetic nephropathy (DN) is an important public health concern of increasing proportions and the leading cause of end-stage renal disease (ESRD) in diabetic patients. It is one of the most common long-term microvascular...