Search Result

Search Results for " ly-2 "

Targets

Compounds

Natural Products

319

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T11904	LY-411575 isomer 2		Others
	LY-411575 isomer 2 is a potent γ-secretase inhibitor. LY-411575 isomer 2 is an isomer of LY411575.		Others
T7706	LY-404187		GluR , iGluR
	LY404187 is a positive allosteric modulator of AMPA receptors		GluR , iGluR
TP1111L1	Tirzepatide sodium salt	LY-3298176 sodium salt,Tirzepatide sodium salt（2023788-19-2 free base）	Glucagon Receptor
	Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity.		Glucagon Receptor
T4310	Prexasertib	LY2606368	Apoptosis , Chk
	Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.		Apoptosis , Chk
T9078	LY3405105	1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester	CDK
	LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester) is a novel CDK7 inhibitors.		CDK
T63149	LY-411575 (isomer 2)
	LY-411575 isomer 2 is an isomer of LY411575. LY411575 is a potent inhibitor of γ-secretase.
T70004	APS-2-79
	APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes ...
T27932	LY-2300559	LY2300559	GluR
	LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.		GluR
T29421	LY195448	4-(3-(2-Hydroxy-2-phenyl)ethylamino-3-methylbutyl)benzamide	Others
	LY 195448 (4-(3-(2-Hydroxy-2-phenyl)ethylamino-3-methylbutyl)benzamide) is a substance present in human blood and urine that shows antitumor activity in a mouse tumor model and blocks cells in the mid-stage.		Others
T1746	LY-2584702 tosylate salt	LY2584702 tosylate	S6 Kinase
	LY-2584702 tosylate salt is a selective, ATP-competitive p70S6K inhibitor, used in trials studying the treatment of cancer.		S6 Kinase
T15826	Lometrexol	LY 264618,DDATHF	DHFR
	Lometrexol (LY 264618), an antipurine Antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit ...		DHFR
T6159	LY-2584702 free base		S6 Kinase , mTOR
	LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).		S6 Kinase , mTOR
T33598	Naveglitazar	LY 9818,LY-519818,LY519818,LY9818,LY-9818,LY 519818
	Naveglitazar (LY 519818, LY 9818) is a peroxisome proliferator-activated receptor (PPAR) modulator, which has entered phase II clinical trials for the treatment of type 2 diabetes.
T11900	LY-2584702 hydrochloride		S6 Kinase
	Ly-2584702 hydrochloride is a p70S6K selective ATP competitive inhibitor with IC50 of 4 nM.In the S6K1 enzyme assay, the IC50 of LY-2584702 was 2 nM.		S6 Kinase
T27960	LY-510929	LY 510929,LY-929,LY 929,LY929,LY510929
	LY-510929, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of hyperlipidaemia, metabolic disorders and type 2 diabetes.
T76272	Pegapamodutide
	Pegapamodutide (LY-2944876) is a dual glucagon-GLP-1 receptor agonist utilized in research concerning type 2 diabetes and obesity [1].
T81672	Nisotirostide	LY-3457263
	Nisotirotide (LY-3457263), a PYY analog agonist, has been investigated for its therapeutic potential in type 2 diabetes and obesity [1].
T76950	Zansecimab
	Zansecimab (LY-3127804), an immunoglobulin G4-kappa monoclonal antibody targeting angiopoietin 2 (Ang 2), exhibits potential in angiogenesis and immune regulation [1] [2] [3].
T38169	LY 341495 disodium salt
	Highly potent and selective group II metabotropic glutamate receptor antagonist. Disodium salt of LY 341495 Fitzjohn et al (1998) The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mG...
T78097	Mazdutide	IBI-362,LY-3305677,OXM-3
	Mazdutide (IBI-362; LY-3305677), a synthetic oxyntomodulin analog, serves as a glucagon-like peptide-1 (GLP-1R)/glucagon receptor (GCGR) co-agonist. Demonstrating safety and tolerability, Mazdutide is utilized in obesity...
T80079	Mazdutide TFA	LY-3305677 TFA,IBI-362 TFA,OXM-3 TFA
	Mazdutide (IBI-362; LY-3305677) TFA is a dual agonist for the glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor (GCGR), also recognized as a long-acting synthetic oxyntomodulin analog. It demonstrates a...
T74415	Imlunestrant tosylate
	Imlunestrant tosylate (LY-3484356) is a potent, orally active selective estrogen receptor degrader (SERD) exhibiting purely antagonistic properties. It effectively maintains inhibition of estrogen receptor (ER)-dependent...
T16578	PRN694		Others
	PRN694 shows extended target residence time on ITK and RLK, enabling durable attenuation of effector cells in vitro and in vivo. PRN694 is an irreversible, highly selective, and effective covalent interleukin-2-inducible...		Others

Compounds

Tirzepatide sodium salt

TP1111L1

Synonym: LY-3298176 sodium salt,Tirzepatide sodium salt（2023788-19-2 free base）

Target: Glucagon Receptor

Prexasertib

T4310

Synonym: LY2606368

Target: Apoptosis, Chk

LY3405105

T9078

Synonym: 1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester

Synonym: 4-(3-(2-Hydroxy-2-phenyl)ethylamino-3-methylbutyl)benzamide

Target: Others

LY-2584702 tosylate salt

T1746

Synonym: LY2584702 tosylate

Target: S6 Kinase

Lometrexol

T15826

Synonym: LY 264618,DDATHF

Target: S6 Kinase, mTOR

Naveglitazar

T33598

Synonym: LY 9818,LY-519818,LY519818,LY9818,LY-9818,LY 519818

Target:

LY-2584702 hydrochloride

Synonym: LY 510929,LY-929,LY 929,LY929,LY510929

LY 341495 disodium salt

Synonym: IBI-362,LY-3305677,OXM-3

Target:

Mazdutide TFA

T80079

Synonym: LY-3305677 TFA,IBI-362 TFA,OXM-3 TFA

Target:

Imlunestrant tosylate

Cat No.	Product Name	Synonyms	Targets
T75635	Microcystin-LY
	Microcystin-LY, a cyclic heptapeptide toxin produced by the cyanobacterium Microcystis aeruginosa [2], functions as a potent activator of the Nrf2 pathway, thereby inducing an oxidative stress response. Its activation ef...

Natural Products

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-05134	CD8 alpha Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293 Cells
	CD8 alpha Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is P01731.
TMPY-01923	CD25/IL2R alpha Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CD25/IL2R alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is P01590.
TMPY-01349	ICAM-1/CD54 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	ICAM-1/CD54 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.7 kDa and the accession number is P13597-1.
TMPY-00800	CD32B/Fcgr2b Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CD32B/Fcgr2b Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.7 kDa and the accession number is A0A0B4J1E6.
TMPY-02358	CD98 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CD98 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P10852-2.
TMPY-04925	CD8 beta Protein, Human, Recombinant, Biotinylated	Human	HEK293 Cells
	CD8 beta Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1.
TMPY-01807	NKp44/NCR2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	NKp44/NCR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is O95944-1.
TMPY-01314	CD8 alpha Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CD8 alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is P01731.
TMPY-05046	CD8 alpha Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CD8 alpha Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.6 kDa and the accession number is P01731.
TMPY-01670	CD2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CD2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P08920.
TMPY-03533	ICAM-2/CD102 Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	ICAM-2/CD102 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23.6 kDa and the accession number is P35330.
TMPY-05544	LY6A Protein, Mouse, Recombinant (His)	Mouse	E. coli
	LY6A Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.9 kDa and the accession number is P05533.
TMPY-01799	ICAM-2/CD102 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	ICAM-2/CD102 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50 kDa and the accession number is P35330.
TMPY-02630	B2M/beta 2-Microglobulin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	B2M/beta 2-Microglobulin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13 kDa and the accession number is P01887.
TMPK-01242	MD2/LY96 Protein, Human, Recombinant (His)	Human	E. coli
	MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocy...
TMPY-05541	CD25/IL2R alpha Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CD25/IL2R alpha Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.4 kDa and the accession number is P01590.
TMPY-06753	ICAM-1/CD54 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	ICAM-1/CD54 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 53.51 kDa and the accession number is P13597.
TMPY-01320	ICAM-1/CD54 Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293 Cells
	ICAM-1/CD54 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 78.3 kDa and the accession number is P13597-1.
TMPK-00632	MD2/LY96 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocy...
TMPY-01206	CD86 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CD86 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is P42082-1.
TMPY-05386	CD86 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CD86 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is P42082-1.
TMPY-01986	CD32B/Fcgr2b Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	CD32B/Fcgr2b Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.9 kDa and the accession number is A0A0B4J1E6.
TMPY-05133	CD86 Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293 Cells
	CD86 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is P42082-1.
TMPY-02925	CD8 beta Protein, Human, Recombinant	Human	HEK293 Cells
	CD8 beta Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1.
TMPY-02703	CD8 beta Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD8 beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44 kDa and the accession number is P10966-1.
TMPY-05367	NKp44/NCR2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	NKp44/NCR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is O95944-1.
TMPY-03999	MD2/LY96 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	LY96 (Lymphocyte Antigen 96, also known as ESOP-1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a protein that associates with toll-like receptor 4 on the cell su...
TMPY-02440	SAP/SH2D1A Protein, Human, Recombinant (His)	Human	E. coli
	SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of...
TMPY-00005	FGF-8a Protein, Human, Recombinant	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-00891	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)	Human	HEK293 Cells
	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
TMPY-00871	LAYN Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	LAYN Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q6UX15-2.
TMPY-00341	FGFR3 Protein, Human, Recombinant (alpha IIIb, His)	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
TMPY-05288	PLGF/PGF Protein, Human, Recombinant (aa 19-149)	Human	E. coli
	PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His)	Human	E. coli
	KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-00748	Nectin-2 Protein, Human, Recombinant	Human	HEK293 Cells
	Nectin-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-00850	ST2/IL-1 RL1 Protein, Human, Recombinant	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2.
TMPY-02792	GDNF Protein, Human, Recombinant (HEK293)	Human	HEK293 Cells
	GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-01691	Clusterin Protein, Human, Recombinant (CLU34, His)	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
TMPY-00849	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2.
TMPY-02011	CD96 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
TMPJ-00850	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPY-01985	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
TMPY-05427	CD19 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
TMPY-02820	SDF-1 Protein, Human, Recombinant (isoform a)	Human	E. coli
	SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPY-04829	G-CSF Protein, Human, Recombinant	Human	HEK293 Cells
	G-CSF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.7 kDa and the accession number is P09919-2.
TMPY-00127	M-CSF/CSF1 Protein, Human, Recombinant	Human	HEK293 Cells
	M-CSF/CSF1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.4 kDa and the accession number is P09603-2.
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPY-02367	Neuropilin-1 Protein, Human, Recombinant (isoform b, His)	Human	HEK293 Cells
	Neuropilin-1 Protein, Human, Recombinant (isoform b, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.3 kDa and the accession number is O14786-2.
TMPY-02096	TACI Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
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