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Search Results for " igg1 "

210

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1357	Human IgG1 Control
	Human IgG1 Control was purified from Human serum by chromatography.Human IgG1 Control can be used as a Control, standard, blocking agent, or coating protein in a variety of experiments, including ELISA, Western and blott...
T78336	Mouse IgG1 kappa, Isotype Control
	Mouse IgG1 kappa Isotype Control is a mouse monoclonal antibody that serves as an isotype control for mouse IgG1κ antibodies.
T78338	Rat IgG1 kappa, Isotype Control
	Rat IgG1 kappa Isotype Control is a rat monoclonal antibody serving as an isotype control specific for Rat IgG1κ antibody.
T81317	Rabbit IgG1 kappa, Isotype Control
	Rabbit IgG1 kappa Isotype Control is a rabbit monoclonal antibody serving as an isotype control for Rabbit IgG1κ antibody.
T78242	Human IgG1 kappa, Isotype Control
	Human IgG1 kappa Isotype Control is a human monoclonal antibody serving as an isotype control specifically for human IgG1κ antibodies [1].
T82157	Human IgG1 lambda1, Isotype Control
	Human IgG1 lambda1 Isotype Control is a chimeric human-mouse monoclonal antibody serving as an isotype control for human IgG1λ1 antibody.
T81759	Mouse IgG1 (N297A) kappa, Isotype Control
	Mouse IgG1 kappa (N297A) Isotype Control is a mouse monoclonal antibody serving as an isotype control specifically for Mouse IgG1(N297A)κ antibodies.
T78341	Human IgG1 (F405L) kappa, Isotype Control
	Human IgG1 (F405L) kappa Isotype Control is a chimeric human-mouse monoclonal antibody serving as an isotype control for the human IgG1 (F405L)κ antibody.
T82159	Human IgG1 (K214R) kappa, Isotype Control
	Human IgG1 (K214R) kappa Isotype Control is a chimeric monoclonal antibody that serves as an isotype control for the human IgG1 (K214R)κ antibody.
T81760	Mouse IgG1 (D265A) kappa, Isotype Control
	Mouse IgG1 (D265A) kappa Isotype Control is a monoclonal antibody that serves as an isotype control for Mouse IgG1 (D265A) κ antibody.
T78340	Human IgG1 (N297A) kappa, Isotype Control
	Human IgG1 (N297A) kappa Isotype Control is a human-mouse chimeric monoclonal antibody serving as an isotype control specifically for the human IgG1 (N297A)κ antibody.
T82160	Human IgG1 (D270N) kappa, Isotype Control
	Human IgG1 (D270N) kappa Isotype Control is a chimeric human-mouse monoclonal antibody that serves as an isotype control for the human IgG1 (D270N)κ antibody.
T82161	Human IgG1 (D265A) kappa, Isotype Control
	Human IgG1 (D265A) kappa Isotype Control is a chimeric monoclonal antibody derived from both human and mouse, designed to serve as an isotype control for the human IgG1 (D265A)κ antibody.
T82158	Human IgG1 (S239D/I332E) kappa, Isotype Control
	Human IgG1 (S239D/I332E) kappa Isotype Control is a chimeric monoclonal antibody derived from human and mouse sequences, serving as an isotype control for the Human IgG1 (S239D/I332E)κ antibody.
T9901	Adalimumab		TNF
	Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.		TNF
T9903	Avelumab		PD-1/PD-L1
	Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity.		PD-1/PD-L1
T78269	Anti-Mouse PD-1 Antibody (RMP1-14)		PD-1/PD-L1
	RMP1-14 is an IgG1-like immunoglobulin and anti-Mouse PD-1 antibody that blocks PD-1/PD-L1 signaling.		PD-1/PD-L1
T76671	Amatuximab	MORab-009	Others
	Amatuximab (MORab-009) is a chimeric IgG1/k monoclonal antibody humanized against cell surface mesoleptin (MSLN) with antitumor activity for the treatment of solid tumors.		Others
T76673	Bemarituzumab	FPA144	FGFR
	Bemarituzumab is a novel humanized IgG1 monoclonal antibody targeting FGFR2b. Bemarituzumab prevents FGFR2b from binding to FGF and activation. Potential applications of Bemarituzumab in cancer research.		FGFR
T77372	Tisotumab	1E10,1.00E+10	Others
	Tisotumab (Anti-Human F3 Recombinant Antibody) is a human IgG1 monoclonal antibody against tissue factor (TF). Tisotumab is involved in antibody-conjugating drugs that can be used to study cancer.		Others
T76866	Icrucumab	LY 3012212,IMC-18F1	VEGFR
	Icrucumab ( IMC-18F1) is a humanized IgG1 monoclonal antibody targeting vascular endothelial growth factor receptor-1.Icrucumab has antitumor activity.Icrucumab has been studied in metastatic colon cancer.		VEGFR
T76735	Mupadolimab	CPI-006	CD73
	Mupadolimab (CPI-006) is a humanized FC-γR binding deficient IgG1 anti-CD73 antibody with potential anticancer activity and activation of CD73POS B cells.		CD73
T77407	Ensituximab	NPC-1C,NEO-102,NEO-101
	Ensituximab (NEO-102) is a quasi-selective IgG1 monoclonal antibody against the MUC5AC variant with anti-tumour activity that inhibits colorectal and pancreatic cancer.
T76706	Varlilumab	CDX-1127	TNF
	Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.		TNF
T77747	Adecatumumab	MT 201	Others
	Adecatumumab (MT201) is a whole-person IgG1 monoclonal antibody to human EpCAM. Adecatumumab has potential anticancer activity and can be used to study breast cancer.		Others
T77748	Tusamitamab		Others
	Tusamitamab is an IgG1 monoclonal antibody targeting CEACAM5 and is the naked antibody to Tusamitamab ravtansine.Tusamitamab can be used to synthesize the antibody-activator coupling Tusamitamab ravtansine.		Others
T76761	Olaratumab	LY3012207,IMC-3G3	PDGFR
	Olaratumab(IMC-3G3) is a human monoclonal IgG1 antibody against platelet-derived growth factor receptor alpha (PDGFRα), which has antitumor effects and can be used to study advanced soft tissue sarcomas.		PDGFR
T35397	Sacituzumab	Sacituzumab,Sacituzumab (anti-Trop-2)
	Sacituzumab is a humanized IgG1 monoclonal antibody, a naked antibody to Sacituzumab govitecan be used to synthesize antibody-active small-molecule couplings.Sacituzumab has potential antitumor activity and is used in th...
T77129	Belantamab	GSK2857914	TNF
	Belantamab (GSK2857914) is a humanized IgG1 monoclonal antibody against BCMA (TNFRSF17). Belantamab is a naked antibody to Belantamab mafodotin and can be used to synthesize antibody-active molecule conjugates (Belantama...		TNF
T77162	Donanemab
	Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody targeting a pyroglutamate amyloid beta (Aβ) epitope at the N-terminus. It shows promise for research in early Alzheimer's disease [1] [2].
T76792	Sibrotuzumab	BIBH 1,Anti-Human FAP Recombinant Antibody	Others
	Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targeting Fibroblast Activating Protein (FAP).Sibrotuzumab is used in the study of colorectal cancer and non-small cell lung cancer.		Others
T9902	Atezolizumab		Apoptosis , PD-1/PD-L1 , Autophagy
	Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1 but not the interaction of PD-L2 with PD-1.		Apoptosis , PD-1/PD-L1 , Autophagy
T77374	Ontuxizumab	MORAb-004	Others
	Ontuxizumab (MORAb-004) is a monoclonal antibody targeting endomelanic acid with anti-tumor effects.Ontuxizumab is a potent IgG1/κ anti-endothelin (TEM-1 or CD248) monoclonal antibody for the treatment of metastatic mela...		Others
T73698	Basiliximab	CHI 621	Interleukin
	Basiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody against the interleukin-2 receptor. Basiliximab has good immunosuppressive activity and can be used in the study of kidney transplantat...		Interleukin
T80622	Trontinemab
	Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC). It is utilized in research on Alzheimer's disease (AD) [1] [2].
T77042	Aducanumab	BIIB037	Beta Amyloid
	Aducanumab (BIIB037), A selective human immunoglobulin gamma-1 (IgG1) monoclonal antibody, targets the clustered form of amyloid beta (Aβ). Aducanumab shows brain permeability and may be used to treat Alzheimer's disease...		Beta Amyloid
T76831	Tesidolumab	LFG316	Complement System
	Tesidolumab (LFG316) is a fully human IgG1/λ anti-C5 monoclonal antibody. Tesidolumab (LFG316) has an inhibitory effect on crovalimab and C5, blocking the cutting of C5 and preventing the subsequent formation of membrane...		Complement System
T0173	Nylidrin hydrochloride	Buphenine HCl	Adrenergic Receptor
	Nylidrin hydrochloride (Buphenine HCl) was an effective inhibitor of the IgG1-mediated release of histamine from passively sensitized guinea pig lung slices, and of the IgE-mediated release of histamine from passively se...		Adrenergic Receptor
T76857	Anetumab		Others
	Anetumab is a novel fully human anti-mesothelin IgG1 antibody that is a naked antibody to Anetumab ravtansine.Anetumab can be used to synthesize the antibody-activated molecule coupling, Anetumab ravtansine.Anetumab can ...		Others
T77170	Siplizumab	MEDI-507	Others
	Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody targeting CD2. Siplizumab selectively depletes effector memory T cells and promotes relative expansion of alloreactive regulatory T cells in vitro. Siplizumab...		Others
T77054	Lecanemab	BAN-2401	Beta Amyloid
	Lecanemab (BAN-2401) is an IgG1 monoclonal antibody targeting soluble aggregated β-amyloid (Abeta) with activity against oligomers, protofibrils, and insoluble protofibrils, and may be useful in the study of Alzheimer's ...		Beta Amyloid
T9901A-002	Enoblituzumab	MGA271,TJ-271	Others
	Enoblituzumab is a humanized IgG1 κmab monoclonal antibody that recognizes human B7-H3 protein and can be used to study solid tumors such as non-small cell lung cancer (NSCLC).		Others
T76696	Onvatilimab	JNJ-61610588	Others
	Onvatilimab (JNJ-61610588) is a human IgG1 κ-anti-Vista (T-cell-activated V-domain Ig inhibitor) monoclonal antibody. Onvatilimab has antitumor activity and can be used to treat advanced head and neck cancers.		Others
T77751	Imaprelimab	PRX-003	Others
	Imaprelimab (PRX-003) is a humanized IgG1 κmonoclonal antibody against melanoma cell adhesion molecule (MCAM). Imaprelimab has antitumor activity and can be used to study inflammation, tumors, and psoriasis.		Others
T38362	Guselkumab	CNTO 1959	IL Receptor
	Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit. Guselkumab binds to human cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab can ...		IL Receptor
T76742	Emapalumab	NI-0501	COX
	Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab ha...		COX
T76892	Ordesekimab	AMG 714,PRV-015	IL Receptor
	Ordesekimab (AMG 714) is a human IgG1 κ-anti-IL-15 (Interleukin Related) monoclonal antibody. Ordesekimab binds competitively to IL-15, inhibiting the interaction of IL-15 with the common gamma chain of the IL-2Rβ and IL...		IL Receptor
T76883	Talacotuzumab	CSL 362,JNJ 56022473	Immunology/Inflammation related , Interleukin
	Talacotuzumab (JNJ 56022473) is an IgG1 fully humanized CD123 neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has a high affinity for CD123, CD32b/c, CD16-158F and CD16-158V, with KD of...		Immunology/Inflammation related , Interleukin
T9921	Infliximab		TNF
	Infliximab is a humanized antibody against tumor necrosis factor α TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis.		TNF
T81050	Talizumab	TNX 901,Anti-Human IgE Fc Recombinant Antibody
	Talizumab (TNX 901), a humanized IgG1 monoclonal antibody, targets IgE [1].

Compounds

Mouse IgG1 kappa, Isotype Control

T78336

Synonym:

Target:

Rat IgG1 kappa, Isotype Control

T78338

Synonym:

Target:

Rabbit IgG1 kappa, Isotype Control

T81317

Synonym:

Target:

Human IgG1 kappa, Isotype Control

T78242

Synonym:

Target:

Human IgG1 lambda1, Isotype Control

T82157

Synonym:

Target:

Mouse IgG1 (N297A) kappa, Isotype Control

T81759

Synonym:

Target:

Human IgG1 (F405L) kappa, Isotype Control

T78341

Synonym:

Target:

Human IgG1 (K214R) kappa, Isotype Control

T82159

Synonym:

Target:

Mouse IgG1 (D265A) kappa, Isotype Control

T81760

Synonym:

Target:

Human IgG1 (N297A) kappa, Isotype Control

T78340

Synonym:

Target:

Human IgG1 (D270N) kappa, Isotype Control

T82160

Synonym:

Target:

Human IgG1 (D265A) kappa, Isotype Control

T82161

Synonym:

Target:

Human IgG1 (S239D/I332E) kappa, Isotype Control

Anti-Mouse PD-1 Antibody (RMP1-14)

Synonym: 1E10,1.00E+10

Target: Others

Icrucumab

T76866

Synonym: LY 3012212,IMC-18F1

Synonym: NPC-1C,NEO-102,NEO-101

Synonym: LY3012207,IMC-3G3

Target: PDGFR

Sacituzumab

T35397

Synonym: Sacituzumab,Sacituzumab (anti-Trop-2)

Synonym: BIBH 1,Anti-Human FAP Recombinant Antibody

Target: Apoptosis, PD-1/PD-L1, Autophagy

Target: Complement System

Nylidrin hydrochloride

T0173

Synonym: Buphenine HCl

Target: Adrenergic Receptor

Synonym: MGA271,TJ-271

Target: Others

Onvatilimab

T76696

Synonym: JNJ-61610588

Synonym: AMG 714,PRV-015

Target: IL Receptor

Talacotuzumab

T76883

Synonym: CSL 362,JNJ 56022473

Target: Immunology/Inflammation related, Interleukin

Synonym: TNX 901,Anti-Human IgE Fc Recombinant Antibody

Target:

Cat No.	Product Name	Synonyms	Targets
TN4804	Platycoside A		Antifection
	Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It induces the IgG and IgG1 antibody responses in the immunized mi...		Antifection

Natural Products

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00820	IgG1 Fc Protein, Human, Recombinant (C103S)	Human	HEK293 Cells
	IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-05138	IgG1 Fc Protein, Human, Recombinant (C103S), Biotinylated	Human	HEK293 Cells
	IgG1 Fc Protein, Human, Recombinant (C103S), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.1 kDa and the accession number is AAC82527.1.
TMPY-06893	IgG1 Fc Protein, Human, Recombinant (C103S, Avi), Biotinylated	Human	HEK293 Cells
	IgG1 Fc Protein, Human, Recombinant (C103S, Avi), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.89 kDa and the accession number is AAC82527.1.
TMPK-00760	IgG1 Fc Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	Recombinant murine Fc fragment contains the hinge region, CH2, and CH3 region of the mouse IgG1 isotype. IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on...
TMPY-06605	IgG1 Fc Protein, Mouse, Recombinant (C102S)	Mouse	HEK293 Cells
	IgG1 Fc Protein, Mouse, Recombinant (C102S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.8 kDa and the accession number is AAK53870.1.
TMPK-00759	IgG1 Fc Protein, Human, Recombinant	Human	HEK293 Cells
	IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflam...
TMPJ-00749	IgG1 hFc Protein, Human, Recombinant	Human	HEK293 Cells
	IgG1 hFc Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32 KDa and the accession number is P01857.
TMPJ-00597	IgG1 hFc Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma ...
TMPJ-00750	IgG1 hFc Protein, Human, Recombinant, Biotinylated	Human	HEK293 Cells
	IgG1 hFc Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 33 KDa and the accession number is P01857.
TMPY-00105	Recombinant Protein G		E. coli
	Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate bindi...
TMPY-05037	CD3E & CD3G Heterodimer Protein, Mouse, Recombinant (hFc & His)	Mouse	HEK293 Cells
	CD3E & CD3G Heterodimer Protein, Mouse, Recombinant (C-human IgG1-Fc & His & C-human IgG1-Fc) is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.4 kDa and the accession number is NP_031674.1&NP_...
TMPY-04964	Recombinant Protein A, HRP conjugate
	Protein A is surface protein originally found in the cell wall of the bacteria Staphylococcusaureus. It is encoded by the spa gene and its regulation is controlled by DNA topology, cellular osmolarity, and a two componen...
TMPK-01115	Fc gamma RIII/CD16 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, ...
TMPK-00641	IgG2C Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	Mouse IgG2c is a subclass of mouse antibody IgG, it can bind FcγRIV with high affinity and the Fc loop residues of mouse IgG2c promote greater receptor-binding affinity than mouse IgG2b or human IgG1.
TMPJ-00893	IgG2a Protein, Rat, Recombinant	Rat	HEK293 Cells
	Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG...
TMPJ-00751	IgG4 hFc Protein, Human, Recombinant (aa 99-326)	Human	HEK293 Cells
	As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma ...
TMPJ-00070	IL-18 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The c...
TMPJ-01337	IL-21R Protein, Mouse, Recombinant (aa 20-236, His)	Mouse	HEK293 Cells
	Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also f...
TMPH-02841	Prohibitin Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regul...
TMPH-02632	TRIM21 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of...
TMPH-02633	TRIM21 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of...