reversible — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T60061	RU-TRAAK-2		Potassium Channel
	RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo1.		Potassium Channel
T9121	AG-636		Dehydrogenase , DNA/RNA Synthesis
	AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.		Dehydrogenase , DNA/RNA Synthesis
T11831	LDN-27219		Others
	LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.		Others
T12909	SID 26681509		Cysteine Protease , Parasite
	SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).		Cysteine Protease , Parasite
T7788	2-Phenyl-2-(1-piperidinyl)propane		Others
	2-Phenyl-2-(1-piperidinyl)propane (PPP), an analog of phencyclidine		Others
T18918	Azure B	Azure B chloride	MAO , Monoamine Oxidase
	Azure B (Azure B chloride) is a cationic dye and the major metabolite of Methylene blue. Azure B is a selective, and reversible inhibitor of MAO-A (IC50s: 11 and 968 nM for recombinant human MAO-A and MAO-B).		MAO , Monoamine Oxidase
T12103	MR-L2		PDE
	MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).		PDE
T9192	BIIB068		BTK
	BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.		BTK
T14897	CCG-63802		GTPase
	CCG-63802 is a reversible inhibitor of the regulator of G-protein signaling (RGS) protein and has the greatest potency at RGS4.		GTPase
T4527	Seclidemstat	SP-2577	Histone Demethylase
	Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.		Histone Demethylase
T28804	Slingshot inhibitor D3	JHN76359	Others
	Slingshot inhibitor D3 (JHN76359) is a potent inhibitor of the Protein Phosphatase Slingshot.		Others
T4337	PCI 29732	PCI29732,PCI-29732	Others , BCRP , BTK
	PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.		Others , BCRP , BTK
T0220	Foscarnet sodium	Phosphonoformate	Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
	Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.		Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
T3185	R112	(E)-Elafibranor	Syk
	R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.		Syk
T3109	SP600125	1PMV,JNK Inhibitor II,Nsc75890,Pyrazolanthrone	Apoptosis , Ferroptosis , Trk receptor , JNK , Aurora Kinase , Autophagy
	SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis.
T11882	Pulrodemstat benzenesulfonate	LSD1-IN-7 benzenesulfonate,CC-90011 benzenesulfonate	Histone Demethylase
	Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.		Histone Demethylase
T3041	ALK inhibitor 2		FAK , ALK
	ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.		FAK , ALK
T10285	ALK inhibitor 1		FAK , IGF-1R , ALK
	ALK inhibitor 1 is a selective ALK kinase inhibitor.		FAK , IGF-1R , ALK
T6S2391	L-Chicoric Acid	(-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid	Others , HIV Protease
	L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ...		Others , HIV Protease
T41143	PCPA methyl ester hydrochloride	4-Chloro-DL-phenylalanine methyl ester hydrochloride	5-HT Receptor , Hydroxylase
	pCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride) is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood...		5-HT Receptor , Hydroxylase