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CCG-63802
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Catalog No. T14897Cas No. 620112-78-9
CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins. CCG-63802 inhibits the interaction between RGS4 and Galpha with an IC50 value of 1.4 μM.
CCG-63802
🥰Excellent
Catalog No. T14897Cas No. 620112-78-9
CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins. CCG-63802 inhibits the interaction between RGS4 and Galpha with an IC50 value of 1.4 μM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $36 | In Stock | |
| 5 mg | $57 | In Stock | |
| 10 mg | $97 | In Stock | |
| 25 mg | $189 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | CCG-63802 is a reversible inhibitor of the regulator of G-protein signaling (RGS) protein and has the greatest potency at RGS4. |
| Targets&IC50 | RGS4:1.4 μM |
| In vitro | CCG-63802 inhibits GTPase accelerating protein activity of RGS4 and blocks its interaction with Gαo. |
| Molecular Weight | 450.51 |
| Formula | C26H18N4O2S |
| Cas No. | 620112-78-9 |
| Smiles | Cc1cccc(Oc2nc3c(C)cccn3c(=O)c2\C=C(/C#N)c2nc3ccccc3s2)c1 |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
| Solubility Information | DMSO: 1.67 mg/mL (3.71 mM), Sonication and heating are recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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