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Seclidemstat

Catalog No. T4527 CAS 1423715-37-0

Synonyms: SP-2577

Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Seclidemstat, CAS 1423715-37-0

Pack Size	Availability	Price/USD
5 mg	In stock	$ 41.00
10 mg	In stock	$ 66.00
25 mg	In stock	$ 123.00
50 mg	In stock	$ 197.00
100 mg	In stock	$ 373.00
200 mg	In stock	$ 556.00
500 mg	In stock	$ 896.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Purity: 98.68%

Purity: 98.28%

Purity: 98.03%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.
Targets&IC50	LSD1:127 nM
In vivo	Interstitial MR lymphography with gadopentetate dimeglumine (Gd-DTPA) allows clear visualization of the lymphatic pathway in healthy mice, and no significant difference is found between the two agents. Their rapid kinetics limits the imaging timing window, however, facilitates repeated assessment in a single imaging session [1]. Direct visualization of spilled gastrointestinal gadopentetate dimeglumine helps discriminate ischemic from control rats in this model [2].

Synonyms	SP-2577
Molecular Weight	450.94
Formula	C20H23ClN4O4S
CAS No.	1423715-37-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: < 0.1 mg/mL (insoluble)

DMSO: 100 mg/mL (221.76 mM), Sonification is recommended.

References and Literature

1. SUBSTITUTED BENZOHYDRAZIDE ANALOGS AS HISTONE DEMETHYLASE INHIBITORS. WO/2017/004519 A1

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Drug Repurposing Compound Library Anti-Cancer Clinical Compound Library Inhibitor Library Anti-Cancer Drug Library Pediatric Drug Library Anti-Cancer Compound Library Chromatin Modification Compound Library Preclinical Compound Library Methylation Compound Library

Related Products

Related compounds with same targets

CP2 KDM4D-IN-1 KDM5-C70 GSK-J1 lithium salt GSK-J4 Hydrochloride 3-pyridine toxoflavin Ryuvidine Methylstat

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Seclidemstat 1423715-37-0 Chromatin/Epigenetic Histone Demethylase Inhibitor replication reversible SWI/SNF SP2577 SP 2577 complex antitumor SP-2577 Ewing DNA inhibit immunity Sarcoma inhibitor

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