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Search Results for " sma "

20

Compounds

Cat No. Product Name Synonyms Targets
T24805 SMA-12b SMA 12b,SMA12b
SMA-12b is an IL-1 inhibitor.
T14080 AA147 ATF6-activator-147 Others
AA147 (ATF6-activator-147) is a small molecule endoplasmic reticulum (ER) proteostasis regulator. The selectively activates ATF6 arm of the unfolded protein response (UPR) .It acts as a prodrug that preferentially trigge...
T4283 SRI-011381 TGF-beta/Smad
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
T4641 Branaplam LMI 070,NVS-SM1 Others , Potassium Channel , DNA/RNA Synthesis
Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.
T5129 SRI-011381 hydrochloride SRI-011381 hydrochloride [1629138-41-5(free base)] TGF-beta/Smad
SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
T16886 Sinefungin Adenosyl-Ornithine,A-9145,Antibiotic 32232RP Others , Histone Methyltransferase , Antibiotic , Antifungal
Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin is a SET7/9 inhibitor and ameliorates r...
T1606 Fasudil HA-1077,AT877 ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy
Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T3060 Fasudil hydrochloride Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877 ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T28466 PSMA-11 HBED-CC-PSMA,Psma-hbed-CC,PSMA11
PSMA-11 (HBED-CC-PSMA) detects prostate cancer recurrence and metastasis by binding to the extracellular structural domain of prostate-specific membrane antigen (PSMA).PSMA-11 is often used as a tracer of PSMA-expressing...
T77019 Garetosmab REGN 2477 TGF-beta/Smad
Garetosmab (REGN 2477) is A whole-human IgG4 monoclonal antibody that selectively inhibits activin A and acts on COVID-19 44. Garetosmab has potential anti-cancer activity and can be used to study ossifying fibrous dyspl...
T13890 SMARCA-BD ligand 1 for Protac dihydrochloride Epigenetic Reader Domain
SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.
T2277 Losmapimod GSK-AHAB,GW856553X,GW856553,SB856553 p38 MAPK , Autophagy
Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).
TN7057 Rosmarinate acid (R)-rosmarinic acid,rosmarinic acid,Rosemary acid MAO , Endogenous Metabolite , Transferase
Rosmarinate acid(Rosemary acid) inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively
T2765 Rosmarinic acid Labiatenic acid,Rosemary acid Apoptosis , IκB/IKK , MAO , Endogenous Metabolite , Transferase , Monoamine Oxidase
Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities. It inhibits MAO-A, MAO-B, and COMT with IC50 of 50.1, 184.6, and 26.7 μM respectively.
T77750 Rosmantuzumab OMP-131R10 Others
Rosmantuzumab (OMP-131R10) is a humanized monoclonal antibody against R-spondin 3 (RSPO3). Rosmantuzumab has potential antitumor activity and can be used to study advanced relapsed refractory solid tumors.
TN6784 Ethyl rosmarinate MMP , Tyrosinase , Glucosidase
ethyl rosmarinate inhibit the activity of tyrosinase, α-glucosidase, and matrix metalloproteinase-1 (MMP-1).
T9568 SGC-SMARCA-BRDVIII Epigenetic Reader Domain
SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM, respectively.
TP1844L Small Cardioactive Peptide B SCPB acetate Small Cardioactive Peptide B SCPB acetate(84746-43-0 free base) Others
Small Cardioactive Peptide B SCPB acetate (Small Cardioactive Peptide B SCPB acetate (84746-43-0 free base)) is a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and ...
T13848 SMARCA-BD ligand 1 for Protac Epigenetic Reader Domain
SMARCA-BD ligand 1 for Protac is a compound capable of binding to SMARCA2, the BAF ATPase subunit, based on the Protac technology for degrading SMARCA2
T19957 Bismaleimide XU 292A,XU-292A,XU292A Others
Bismaleimide (XU 292A) has heat resistance, oxidation resistance and radiation resistance, and can be used to prepare electrical insulation materials, wear-resistant materials, reinforced plastic additives, grinding whee...

Compounds

SMA-12b
T24805
Synonym: SMA 12b,SMA12b
Target:
AA147
T14080
Synonym: ATF6-activator-147
Target: Others
SRI-011381
T4283
Synonym:
Target: TGF-beta/Smad
Branaplam
T4641
Synonym: LMI 070,NVS-SM1
Target: Others, Potassium Channel, DNA/RNA Synthesis
SRI-011381 hydrochloride
T5129
Synonym: SRI-011381 hydrochloride [1629138-41-5(free base)]
Target: TGF-beta/Smad
Sinefungin
T16886
Synonym: Adenosyl-Ornithine,A-9145,Antibiotic 32232RP
Target: Others, Histone Methyltransferase, Antibiotic, Antifungal
Fasudil
T1606
Synonym: HA-1077,AT877
Target: ROCK, Serine/threonin kinase, Calcium Channel, PKA, PKC, Autophagy
Fasudil hydrochloride
T3060
Synonym: Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877
Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy
PSMA-11
T28466
Synonym: HBED-CC-PSMA,Psma-hbed-CC,PSMA11
Target:
Garetosmab
T77019
Synonym: REGN 2477
Target: TGF-beta/Smad
SMARCA-BD ligand 1 for Protac dihydrochloride
T13890
Synonym:
Target: Epigenetic Reader Domain
Losmapimod
T2277
Synonym: GSK-AHAB,GW856553X,GW856553,SB856553
Target: p38 MAPK, Autophagy
rosmarinate acid
TN7057
Synonym: (R)-rosmarinic acid,rosmarinic acid,Rosemary acid
Target: MAO, Endogenous Metabolite, Transferase
Rosmarinic acid
T2765
Synonym: Labiatenic acid,Rosemary acid
Target: Apoptosis, IκB/IKK, MAO, Endogenous Metabolite, Transferase, Monoamine Oxidase
Rosmantuzumab
T77750
Synonym: OMP-131R10
Target: Others
ethyl rosmarinate
TN6784
Synonym:
Target: MMP, Tyrosinase, Glucosidase
SGC-SMARCA-BRDVIII
T9568
Synonym:
Target: Epigenetic Reader Domain
Small Cardioactive Peptide B SCPB acetate
TP1844L
Synonym: Small Cardioactive Peptide B SCPB acetate(84746-43-0 free base)
Target: Others
SMARCA-BD ligand 1 for Protac
T13848
Synonym:
Target: Epigenetic Reader Domain
Bismaleimide
T19957
Synonym: XU 292A,XU-292A,XU292A
Target: Others
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TargetMol