cycle — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T77753	EBV lytic cycle inducer-1	Dp44mT	Antifection
	EBV lytic cycle inducer-1 is an iron chelate analogue that induces the lytic cycle of EBV.		Antifection
T4862	Oxaloacetic acid		Endogenous Metabolite
	Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate (the ionized form of oxaloacetic acid) ...		Endogenous Metabolite
T9628	10074-A4		c-Myc
	10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from that of a non-binding ligand.		c-Myc
T22336	Galloflavin		Dehydrogenase
	Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 µM and 15.06 µM, respectively. Galloflavin is also a potential anticancer agent.		Dehydrogenase
T11960	MBM-55		GSK-3 , MAPK , DYRK , Akt , Chk , Bcr-Abl , CDK , S6 Kinase , Aurora Kinase
	MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM. MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis.
TN2190	Scoulerine		Apoptosis , Beta-Secretase , BACE , Parasite
	Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells.		Apoptosis , Beta-Secretase , BACE , Parasite
T10857	Coenzyme A		Endogenous Metabolite
	Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.		Endogenous Metabolite
T8762	SW106065	SW-106065	Apoptosis
	SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors).SW106065 is an apoptosis inducer in malignant peripheral nerve sheath tumors (MPNST). It inhibits ATP consumption...		Apoptosis
TN2069	Picrocrocin		Apoptosis
	Picrocrocin is a natural product		Apoptosis
T4470	Pyridostatin TFA		DNA/RNA Synthesis
	Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-kit, K-ras and Bcl-2.		DNA/RNA Synthesis
T21970	ML-097		GTPase
	ML-097 (CID-2160985) is a pan activator of Ras-related GTPases		GTPase
T60037	SR15006		DNA/RNA Synthesis
	SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).		DNA/RNA Synthesis
T8916	WEE1-IN-3	JUN76288	Wee1
	WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases.		Wee1
T21331	SAR-020106		Chk
	SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme.		Chk
T21679	4'-bromo-Resveratrol		Sirtuin
	4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3)		Sirtuin
T14066	9-ING-41		Apoptosis , GSK-3 , Autophagy
	9-ING-41 is a glycogen synthase kinase-3 inhibitor.		Apoptosis , GSK-3 , Autophagy
T23133	Pentamidine		Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal
	Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication.
T9244	σ1 Receptor antagonist-1		Sigma receptor
	σ1 Receptor antagonist-1 is a selective sigma 1 receptor antagonist.		Sigma receptor
T6207	SC144		Apoptosis , Interleukin
	SC144 is an orally active small-molecule gp130 inhibitor.		Apoptosis , Interleukin
TN1727	Helichrysetin		Apoptosis , HIV Protease
	Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.		Apoptosis , HIV Protease