Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors).SW106065 is an apoptosis inducer in malignant peripheral nerve sheath tumors (MPNST). It inhibits ATP consumption of sMPNST and other models of MPNST with an EC50 of 1 μM. SW106065 can be used for MPNST research
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 43.00 | |
2 mg | In stock | $ 63.00 | |
5 mg | In stock | $ 109.00 | |
10 mg | In stock | $ 172.00 | |
25 mg | In stock | $ 313.00 | |
50 mg | In stock | $ 493.00 | |
100 mg | In stock | $ 725.00 | |
500 mg | In stock | $ 1,520.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 122.00 |
Description | SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors).SW106065 is an apoptosis inducer in malignant peripheral nerve sheath tumors (MPNST). It inhibits ATP consumption of sMPNST and other models of MPNST with an EC50 of 1 μM. SW106065 can be used for MPNST research |
In vitro | SW-106065 inhibits growth of all available in vitro models of MPNST and human MPNST cell lines, while remaining nontoxic to normally dividing Schwann cells or mouse embryonic fibroblasts. We This compound delays the cell cycle and leads to cellular apoptosis. |
In vivo | SW-106065 can reduce MPNST burden in a mouse allograft model, underscoring the compound's potential as a novel chemotherapeutic agent. |
Synonyms | SW-106065 |
Molecular Weight | 204.25 |
Formula | C10H8N2OS |
CAS No. | 62289-81-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 96 mg/mL (470 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SW106065 62289-81-0 Apoptosis SW 106065 cell cdk4 Inhibitor MPNST cycle ATP anticancer cdk6 cyclin SW-106065 inhibit inhibitor