Powder: -20°C for 3 years | In solvent: -80°C for 1 year
10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from that of a non-binding ligand.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 108.00 | |
5 mg | In stock | $ 228.00 | |
10 mg | In stock | $ 347.00 | |
25 mg | In stock | $ 589.00 | |
50 mg | In stock | $ 842.00 | |
100 mg | In stock | $ 1,160.00 | |
500 mg | In stock | $ 2,330.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 263.00 |
Description | 10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from that of a non-binding ligand. |
Targets&IC50 | c-Myc:15.1 ± 2.3 μM(EC50), c-Myc:36.3 ± 9.0 μM(Kd) |
In vitro | 10074-A4 showed binding affinity with c-Myc370–409 with Kd of 36.3?±?9.0?μM and EC50 of 15.1?±?2.3?μM[2].10074-A4 arrests the cell cycle at the S-phase in a dose-dependent manner in HL-60 cells[2]. |
Molecular Weight | 409.29 |
Formula | C18H14Cl2N2O3S |
CAS No. | 312631-87-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (244.33 mM)
You can also refer to dose conversion for different animals. More
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10074-A4 312631-87-1 Cell Cycle/Checkpoint c-Myc Inhibitor 10074-A-4 anticancer cycle CDK4 inhibit cell 10074A4 Myc CCND2 10074 A4 inhibitor