cultures — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4601	9-Methoxycanthin-6-one		Others
	9-Methoxycanthin-6-one has anti-tumour activity, exhibits cytotoxic activity towards KB, LU-1, LNCaP, HL-60 cancer cells and other human cancer cell lines with IC50 values around 1-4 μg/mL.		Others
T4277	Osilodrostat	LCI699	Glucocorticoid Receptor , Others , Hydroxylase
	Osilodrostat (LCI699) (LCI699) is an effective inhibitor of human 11β-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM).		Glucocorticoid Receptor , Others , Hydroxylase
TQ0265	Indolelactic acid		Endogenous Metabolite
	Indolelactic acid is a metabolite of tryptophan in Azotobacter vinelandii cultures.		Endogenous Metabolite
T31425	Dibenz[a,h]anthracene	CCRIS 208,NSC 22433,AI3-18996,DB(a,h)A	DNA
	Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell cultures.		DNA
T21012	Diflufenican	M&B 38544	Others
	Diflufenican (M&B 38544) increases the production of phytoene in carrot cell cultures by inducing the inhibition of phytoene desaturase gene expression.		Others
T8458	CNQX disodium		iGluR
	CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.		iGluR
T60086	TTBK1-IN-2	N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Microtubule Associated
	TTBK1-IN-2 (N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine) is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 µM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures ...		Microtubule Associated
T1003	Tylosin	Fradizine,Tylosin A,Tylosine,Tylocine	Antibacterial , Antibiotic
	Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.		Antibacterial , Antibiotic
T5285	3-(Methylthio)propionic acid	3-Methylthiopropionate,4-Thiapentanoic acid,3-Methylsulfanylpropionic acid	Others , Endogenous Metabolite , Antifungal
	3-(Methylthio)propionic acid (4-Thiapentanoic acid) is one of the metabolites of methionine (especially of D-methionine). Cultures of Streptomyces lincolnensis accumulated 3-methylthioacrylic acid in amounts directly rel...		Others , Endogenous Metabolite , Antifungal
T3031	A 83-01	ALK5 Inhibitor IV,A8301	ALK , TGF-beta/Smad
	A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-β type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM). A 83-01 promotes the reprogramming of mouse fibroblasts into iPSCs. A 83-01 can be used in organoid cult...		ALK , TGF-beta/Smad
T1506	Vidarabine	Adenine Arabinoside,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A	Nucleoside Antimetabolite/Analog , Tyrosine Kinases , DNA/RNA Synthesis , Antibiotic , HSV
	Vidarabine (Adenine Arabinoside) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and signific...
T60197	UNC 1025		Others
	UNC1062 is a highly selective tyrosine kinase inhibitor that specifically targets MERTK. This compound effectively suppresses MERTK-mediated downstream signaling, induces apoptosis in cell cultures, reduces colony format...		Others
T37742	N-hexanoyl-DL-Homoserine lactone	C6-HSL	Antibiotic
	N-hexanoyl-DL-Homoserine lactone (C6-HSL), isolated from bivalve larval cultures, degrades bacteria and inhibits lesions induced by the phytopathogenic fungus B. cinerea.N-hexanoyl-DL-Homoserine lactone participates in t...		Antibiotic
T3486	3-MATIDA		GluR , NMDAR
	3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM). 3...		GluR , NMDAR
T26684	Auten-99 HBr	Auten-99,Auten-99 hydrochloride. Auten-99 HBr,Auten99,Auten 99	Phosphatase
	Auten-99 HBr (Auten-99) is a myotubularin phosphatase Jumpy inhibitor exerting potent neuroprotective effects. AUTEN-99 activates autophagy in cell cultures and animal models. AUTEN-99 appears to effectively penetrate th...		Phosphatase
T3923	Calycosin	Cyclosin,3'-Hydroxyformononetin	Apoptosis , Tyrosinase
	Calycosin (Cyclosin) acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Calycosin suppresses breast cancer c...		Apoptosis , Tyrosinase
T6202	DAPT	LY-374973,GSI-IX	Apoptosis , Beta Amyloid , Gamma-secretase , Autophagy
	DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces cell differentiation, autophagy and apoptosis.		Apoptosis , Beta Amyloid , Gamma-secretase , Autophagy
T25762	Lucimycin	FI1163,Antibiotic 1163 F.I.,FI 1163,FI-1163,NSC 143257
	Lucimycin is a macrolide antibiotic from cultures of Streptomyces lucensis.
T25699	Levorin	Levorinum,Levorina,Levorine
	Levorin is a polyene series antibiotic, obtained from cultures of Actinomyces levoris.
T32836	Lochnericine
	Lochnericine is a alkaloid isolated from elicited cell cultures of Catharanthus roseus.