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Dibenz[a,h]anthracene

Catalog No. T31425   CAS 53-70-3
Synonyms: CCRIS 208, NSC 22433, AI3-18996, DB(a,h)A

Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell cultures.

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Dibenz[a,h]anthracene Chemical Structure
Dibenz[a,h]anthracene, CAS 53-70-3
Pack Size Availability Price/USD Quantity
50 mg In stock $ 50.00
100 mg In stock $ 75.00
1 mL * 10 mM (in DMSO) In stock $ 45.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell cultures.
Synonyms CCRIS 208, NSC 22433, AI3-18996, DB(a,h)A
Molecular Weight 278.35
Formula C22H14
CAS No. 53-70-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 3.6 mg/mL (12.93 mM)

TargetMolReferences and Literature

1. Padilla-Chavarría HI, Guizado TR, Pimentel AS. Molecular dynamics of dibenz[a,h]anthracene and its metabolite interacting with lung surfactant phospholipid bilayers. Phys Chem Chem Phys. 2015 Aug 28;17(32):20912-22. doi: 10.1039/c5cp01443c. Epub 2015 Jul 27. PubMed PMID: 26214736. 2. Chang RL, Wood AW, Huang MT, Xie JG, Cui XX, Reuhl KR, Boyd DR, Lin Y, Shih WJ, Balani SK, Yagi H, Jerina DM, Conney AH. Mutagenicity and tumorigenicity of the four enantiopure bay-region 3,4-diol-1,2-epoxide isomers of dibenz[a,h]anthracene. Carcinogenesis. 2013 Sep;34(9):2184-91. doi: 10.1093/carcin/bgt164. Epub 2013 May 13. PubMed PMID: 23671133; PubMed Central PMCID: PMC3765047. 3. Malik AI, Rowan-Carroll A, Williams A, Lemieux CL, Long AS, Arlt VM, Phillips DH, White PA, Yauk CL. Hepatic genotoxicity and toxicogenomic responses in Muta™Mouse males treated with dibenz[a,h]anthracene. Mutagenesis. 2013 Sep;28(5):543-54. doi: 10.1093/mutage/get031. Epub 2013 Jun 21. PubMed PMID: 23793610. 4. Kim JH, Kim WK. Use of the Integrated Biomarker Response to Measure the Effect of Short-term Exposure to Dibenz[a,h]anthracene in Common carp (Cyprinus carpio). Bull Environ Contam Toxicol. 2016 Apr;96(4):496-501. doi: 10.1007/s00128-015-1726-y. Epub 2016 Jan 7. PubMed PMID: 26744022.

Related compound libraries

This product is contained In the following compound libraries:
Bioactive Compounds Library Max DNA Damage & Repair Compound Library Bioactive Compound Library

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Keywords

Dibenz[a,h]anthracene 53-70-3 DNA Damage/DNA Repair DNA CCRIS 208 NSC 22433 CCRIS-208 NSC-22433 CCRIS208 AI3-18996 DB(a,h)A NSC22433 inhibitor inhibit

 

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